Abstract: Disclosed herein are novel lipids that can be used in combination with other lipid components, such as helper lipids, structural lipids, and cholesterols, to form lipid nanoparticles for delivery of therapeutic agents, such as nucleic acids (e.g., circular polynucleotides), both in vitro and in vivo.

Abstract: Disclosed herein are novel lipids that can be used in combination with other lipid components, such as helper lipids, structural lipids, and cholesterols, to form lipid nanoparticles for delivery of therapeutic agents, such as nucleic acids (e.g., circular polynucleotides), both in vitro and in vivo.

Abstract: A mobile power source that has a battery pack including at least two battery cell assemblies each having frame that has a first support member and a second support member, each of the first and second support members including a plurality of cylindrical recesses that receive the plurality of battery cells to support the battery cells. Bus bars are coupled to the first support member via injection molding and each is configured to electrically connect to at least two battery cells. The bus bars each include an elongated conductive body that has a base and fingers extending laterally away from the base. Each of the fingers extend within a first plane, and the base extends within a second plane that is parallel to the first plane and offset therefrom.

Abstract: The present disclosure pertains to sample preparation devices useful for affinity capture and purification that include one or more internal structures that comprise a reservoir, a well, a fluid passageway, sorbent particles, and a filter element that blocks passage of the affinity sorbent particles, which sample preparation devices combine the attributes of both dispersive and flow through designs into a single sample preparation device. The present disclosure also pertains to kits that contain and methods that use such sample preparation devices.

Abstract: A system including a network interface and a processing circuit is provided. The processing circuit includes one or more processors coupled to non-transitory memory. The processing circuit is structured to receive a request for a multiple custody linkage between user devices. The multiple custody linkage includes a digital connection between the user devices that allows shared access to a resource. The resource includes at least one of a physical object or information. The processing circuit is further structured to perform a validation process based on information in the request for the multiple custody linkage to determine if a violation of a security protocol exists. The security protocol is associated with security of the resource. The processing circuit is further structured to, in response to determining no violation of the security protocol exists, activate the multiple custody linkage between the user devices to allow the shared access to the resource.

Abstract: A photocathode epitaxial structure. The photocathode epitaxial structure includes a binary compound substrate material. The photocathode epitaxial structure further includes an active device absorber layer forming a portion of a p-type device photocathode formed on the binary compound substrate material. The active device absorber layer comprising at least a quaternary or greater material structure configured to be lattice matched with the substrate material to reduce strain to allow charge carriers to go further in the active device absorber layer implemented in the photocathode of a nightvision system.

Abstract: A photocathode. The photocathode includes an absorber. The absorber a p-type bulk active layer and a plurality of nanostructures formed on the p-type bulk active layer. The Photocathode further includes the plurality of nanostructures, such that the plurality of nanostructures are formed at a band bending region between the bulk active layer and the vacuum.

Abstract: Disclosed herein are novel lipids that can be used in combination with other lipid components, such as helper lipids, structural lipids, and cholesterols, to form lipid nanoparticles for delivery of therapeutic agents, such as nucleic acids (e.g., circular polynucleotides), both in vitro and in vivo.

Abstract: A sprayer includes a spray gun and a hopper. An air source provides compressed air to the sprayer to both eject fluid from the spray gun as a spray and to pressurize the hopper. The spray gun includes passages for providing compressed air to the nozzle for spraying and to the hopper for pressurizing the hopper. The spray gun further includes a relief valve for venting pressurized air from the hopper. The hopper receives the compressed air through a port in the hopper, and the compressed air assists the flow of material out of the hopper and into the spray gun.

Abstract: The assembly includes a docking console and a manifold. The docking console includes a cartridge support surface having a first end and a second end. The manifold has one or more wells defined therein. The docking console further includes a manifold retention bracket to releasably hold the manifold against a fluid cartridge supported on the cartridge support surface at an interface position such that the one or more wells are in fluid communication with the fluid cartridge and a biased seal bar to press the fluid cartridge against the manifold held by the manifold retention bracket. A hydrophilic porous frit disposed within at least one of the wells and is to permit liquid to flow through the outlet aperture but prevent gas from passing through the outlet aperture.

Abstract: A photocathode epitaxial structure. The photocathode epitaxial structure includes an improved substrate stack. The improved substrate stack includes a GaAs substrate and one or more additional layers formed on the GaAs substrate. The one or more additional layers are configured to provide an improved substrate stack surface with predetermined characteristics for forming a semiconductor device on the improved substrate stack surface. The photocathode epitaxial structure further includes an InGaAs p-type photocathode formed on the improved substrate stack surface. The InGaAs p-type photocathode has a predetermined percentage of In.

Abstract: An agricultural implement includes a plurality of ground-engaging tools configured to modify a surface configuration of an agricultural field and a hydraulically-controlled subsystem configured to modify an operating angle of the plurality of ground-engaging tools. The agricultural implement also includes a sensor coupled to the hydraulically-controlled subsystem configured to generate sensor signals indicative of a current operating angle of the plurality of ground-engaging tools. The agricultural implement also includes an implement control system configured to receive the sensor signals from the sensor to determine the current operating angle of the plurality of ground-engaging tools, and, upon determining the current operating angle is to be changed to a new operating angle, generate control signals for the hydraulically-controlled subsystem to modify the operating angle of the plurality of ground-engaging tools from the current operating angle to the new operating angle.

Abstract: Certain aspects of the present disclosure provide techniques for rendering visual artifacts in virtual worlds using machine learning models. An example method generally includes identifying, based on a machine learning model and a streaming natural language input, an intent associated with the streaming natural language input; generating, based on the identified intent associated with the streaming natural language input, one or more virtual objects for rendering in a virtual environment displayed on one or more displays of an electronic device; and rendering the generated one or more virtual objects in the virtual environment.

Abstract: A powder spray gun includes a powder flow path inlet and a powder flow path outlet, the powder flow path inlet being connectable in a first configuration to a dilute phase powder pump and in a second configuration to a dense phase powder pump, wherein the powder spray gun comprises a spray nozzle that is the same for the first and second configurations. The powder flow path is provided by a powder tube that extends through the gun, with the powder tube having a first diameter at an inlet portion of the spray gun and a second diameter at an outlet portion of the spray gun, with the second diameter being greater than the first diameter. The powder flow path may also include a conical transition portion, and a member for adding air to the powder flow.

Abstract: A mobility device configurable in a first walk configuration and a second stair-climb configuration, including a frame with movable front leg portions, a leg-actuation system connected to the front leg portions and a safety-control device mounted to the frame. The safety-control device includes a configuration selector, and a lever connected to the leg-actuation system and configured to actuate the cable actuation system so as to cause the first and second movable leg portions to move from a first position to a second position. The lever remains locked in a first lever position such that the lever cannot be moved unless the configuration selector is in a depressed position, thereby preventing inadvertent movement of the leg portion.

Abstract: Disclosed herein are novel lipids that can be used in combination with other lipid components, such as helper lipids, structural lipids, and cholesterols, to form lipid nanoparticles for delivery of therapeutic agents, such as nucleic acids (e.g., circular polynucleotides), both in vitro and in vivo.

Abstract: An apparatus and method are provided for a night vision system including a transparent overlay display that transmit direct-view light representing an intensified image and emits display light representing a display image. The overlay display includes photodetectors arranged to detect an intensity of the incoming direct-view light, and an intensity of the display light depends on the detected intensity. In some embodiments, the intensity of the display light is spatially modulated using an amplitude or envelope of the intensity that is based on the detected local intensity of the direct-view light. In some embodiments, the intensity of the display light is adjusted to correct for loss of the direct-view light. The intensity of the display light may be controlled using control circuitry that receives signals from the photodetectors, and the control circuitry may be located on the same semiconductor chip as the overlay display.

Abstract: An electric tool is provided with a second switch that is actuated in order for the tool to be used. The second switch is on a second handle that is grasped by the operator with a different hand than the hand that actuates the main trigger switch. Communication between the second switch and the tool occurs with a wireless signal indicating that the second switch has been actuated.

Abstract: A method, computer program product, and system are provided. A first natural language text is received via a user interface. A generative pretrained transformer machine learning model processes the first natural language text and a context to identify a first intent. The processing is based in part on a syntax determined from a set of natural language completion paradigms. The generative transformer machine learning model maps the first set of parameters to a first query. The mapping is associated with a first confidence. The generative transformer machine learning model processes the first set of parameters and the first query to generate a set of execution steps. The processing is performed when the first confidence satisfies a threshold. The set of execution steps is parsed into a query object that is forwarded to a reporting service.

Abstract: An optical device includes an underlying device configured to output light in a first spectrum. A stacked device is coupled to the underlying device and configured to be coupled in overlapping fashion to an optical output of the underlying device. The stacked device is transparent to light in the first spectrum. The stacked device includes electro-optical circuits including: light emitters and detectors. Each detector is associated with one or more light emitters. Each detector is configured to detect light emitted from the underlying device. The light emitters are configured to output light dependent on light detected by an associated detector. Optical filters are optically coupled to an optical input of the underlying device. Each filter is aligned with a detector to suppress absorption of certain wavelengths of light by the underlying device thereby affecting light detected by the detectors and thus further affecting the light output by the light emitters.