Patents by Inventor J. Beltran
J. Beltran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11963909Abstract: A method and surgical system including a laser source for generating a pulsed laser beam, an imaging system including a detector, shared optics configured for directing the pulsed laser beam to an object to be sampled and confocally deflecting back-reflected light from the object to the detector, a patient interface, through which the pulsed laser beam is directed, the patient interface having, a cup with a large and small opening, and a notched ring inside the cup; and a controller operatively coupled to the laser source, the imaging system and the shared optics, the controller configured to align the eye for procedure.Type: GrantFiled: October 14, 2019Date of Patent: April 23, 2024Assignee: AMO Development, LLCInventors: John S. Hart, David A. Dewey, Georg Schuele, Phillip H. Gooding, Christine J. Beltran, Javier G. Gonzalez, Katrina B. Sheehy, Jeffrey A. Golda, Raymond Woo, Madeleine C. O'Meara, Noah Bareket, Thomas Z. Teisseyre, Bruce Woodley
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Publication number: 20230264041Abstract: A variable thickness energy selection system for use in a charged particle therapy system is arranged within the nozzle housing downstream of monitoring systems, such as a dose monitor and spot position monitor. This positions the energy selection system proximal to the patient. The thickness of an absorber within the energy selection system can be varied quickly without requiring the ion beam to be turned off between energy selections, thereby allowing for rapid control of the energy selection of the ion beam. The absorber may include one or more high density solid absorbers, or a high-density liquid absorber contained in a closed fluid dynamic system that includes an enclosure positioned within the beam path and a reservoir positioned outside of the beam path.Type: ApplicationFiled: July 2, 2021Publication date: August 24, 2023Inventors: Chris J. Beltran, Keith M. Furutani
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Publication number: 20230099519Abstract: The present invention is directed to a platform for the tracking and management of stress encountered by a user. Biometric data corresponding to the stress of the user is collected and analyzed to determine the stress level of a user. In one embodiment, this data is cross-referenced with data such as data from a user's calendar operable to provide context and/or reason to the stress level. Based on the data, conversation models and resources are operable to be provided to the user to help in mitigating and managing stress.Type: ApplicationFiled: March 16, 2022Publication date: March 30, 2023Applicant: Fierce, Inc.Inventor: Edward J. Beltran
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Patent number: 11253396Abstract: A laser eye surgery system that has a patient interface between the eye and the laser system relying on suction to hold the interface to the eye, the patient interface using liquid used as a transmission medium for the laser. During a laser procedure sensors monitor the level of liquid within the patient interface and send a signal to control electronics if the level drops below a threshold value. The sensor may be mounted on the inside of the patient interface, within a fluid chamber. Alternatively, a gas flow meter may be added to a suction circuit for the patient interface that detects abnormal suction levels indicating low fluid level.Type: GrantFiled: September 9, 2019Date of Patent: February 22, 2022Assignee: AMO Development, LLCInventors: Phillip H. Gooding, Christine J. Beltran, Brent Eikanas, Michael A. Campos
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Patent number: 11078288Abstract: The present invention provides, in part, methods for treating a tumor in a human subject comprising inhibiting IGF-1 receptor signaling, methods of determining whether a tumor is more or less likely to respond to such treatment, and compositions for practicing such methods. In particular embodiments, the invention provides fully human, humanized, or chimeric anti-IGF-1R antibodies that bind human IGF-1R, IGF-1R-binding fragments and derivatives of such antibodies, and IGF-1R-binding polypeptides comprising such fragments. Other embodiments provide nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods of making such antibodies, antibody fragments and derivatives and polypeptides, and methods of using such antibodies, antibody fragments and derivatives and polypeptides, including methods of treating or diagnosing subjects having IGF-1R-related disorders or conditions.Type: GrantFiled: April 17, 2018Date of Patent: August 3, 2021Assignee: Amgen Inc.Inventors: Pedro J. Beltran, Frank J. Calzone, Gregory Friberg, Christopher Haqq, Anthony W. Tolcher
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Publication number: 20200038245Abstract: A method and surgical system including a laser source for generating a pulsed laser beam, an imaging system including a detector, shared optics configured for directing the pulsed laser beam to an object to be sampled and confocally deflecting back-reflected light from the object to the detector, a patient interface, through which the pulsed laser beam is directed, the patient interface having, a cup with a large and small opening, and a notched ring inside the cup; and a controller operatively coupled to the laser source, the imaging system and the shared optics, the controller configured to align the eye for procedure.Type: ApplicationFiled: October 14, 2019Publication date: February 6, 2020Inventors: John S. Hart, David A. Dewey, Georg Schuele, Phillip H. Gooding, Christine J. Beltran, Javier G. Gonzalez, Katrina B. Sheehy, Jeffrey A. Golda, Raymond Woo, Madeleine C. O'Meara, Noah Bareket, Thomas Z. Teisseyre, Bruce Woodley
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Publication number: 20200009204Abstract: The present invention relates to the use of oncolytic viruses (e.g., talimogene laherparepvec), either alone or in combination with immune checkpoint inhibitors (e.g., anti-CTLA-4, anti-PD-1, and anti-PD-L1 compounds such an antibodies) for the treatment of various types of cancer. In addition, the present invention relates to compositions and kits relating to such uses of oncolytic viruses, either alone or in combination with immune checkpoint inhibitors.Type: ApplicationFiled: March 14, 2018Publication date: January 9, 2020Inventors: Pedro J. BELTRAN, Courtney BEERS, Keegan COOKE
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Publication number: 20190388269Abstract: A laser eye surgery system that has a patient interface between the eye and the laser system relying on suction to hold the interface to the eye, the patient interface using liquid used as a transmission medium for the laser. During a laser procedure sensors monitor the level of liquid within the patient interface and send a signal to control electronics if the level drops below a threshold value. The sensor may be mounted on the inside of the patient interface, within a fluid chamber. Alternatively, a gas flow meter may be added to a suction circuit for the patient interface that detects abnormal suction levels indicating low fluid level.Type: ApplicationFiled: September 9, 2019Publication date: December 26, 2019Inventors: Phillip H. Gooding, Christine J. Beltran, Brent Eikanas, Michael A. Campos
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Patent number: 10441465Abstract: A method and surgical system including a laser source for generating a pulsed laser beam, an imaging system including a detector, shared optics configured for directing the pulsed laser beam to an object to be sampled and confocally deflecting back-reflected light from the object to the detector, a patient interface, through which the pulsed laser beam is directed, the patient interface having, a cup with a large and small opening, and a notched ring inside the cup; and a controller operatively coupled to the laser source, the imaging system and the shared optics, the controller configured to align the eye for procedure.Type: GrantFiled: April 26, 2016Date of Patent: October 15, 2019Assignee: OPTIMEDICA CORPORATIONInventors: John S. Hart, David A. Dewey, Georg Schuele, Phillip H. Gooding, Christine J. Beltran, Javier G. Gonzalez, Katrina B. Sheehy, Jeffrey A. Golda, Raymond Woo, Madeleine C. O'Meara, Noah Bareket, Thomas Z. Teisseyre, Bruce Woodley
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Patent number: 10406032Abstract: A laser eye surgery system that has a patient interface between the eye and the laser system relying on suction to hold the interface to the eye, the patient interface using liquid used as a transmission medium for the laser. During a laser procedure sensors monitor the level of liquid within the patient interface and send a signal to control electronics if the level drops below a threshold value. The sensor may be mounted on the inside of the patient interface, within a fluid chamber. Alternatively, a gas flow meter may be added to a suction circuit for the patient interface that detects abnormal suction levels indicating low fluid level.Type: GrantFiled: December 16, 2015Date of Patent: September 10, 2019Assignee: OPTIMEDICA CORPORATIONInventors: Phillip H. Gooding, Christine J. Beltran, Brent Eikanas, Michael A. Campos
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Publication number: 20190040141Abstract: The present invention provides, in part, methods for treating a tumor in a human subject comprising inhibiting IGF-1 receptor signaling, methods of determining whether a tumor is more or less likely to respond to such treatment, and compositions for practicing such methods. In particular embodiments, the invention provides fully human, humanized, or chimeric anti-IGF-1R antibodies that bind human IGF-1R, IGF-1R-binding fragments and derivatives of such antibodies, and IGF-1R-binding polypeptides comprising such fragments. Other embodiments provide nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods of making such antibodies, antibody fragments and derivatives and polypeptides, and methods of using such antibodies, antibody fragments and derivatives and polypeptides, including methods of treating or diagnosing subjects having IGF-1R-related disorders or conditions.Type: ApplicationFiled: April 17, 2018Publication date: February 7, 2019Inventors: Pedro J. BELTRAN, Frank J. CALZONE, Gregory FRIBERG, Christopher HAQQ, Anthony W. TOLCHER
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Publication number: 20160235588Abstract: A method and surgical system including a laser source for generating a pulsed laser beam, an imaging system including a detector, shared optics configured for directing the pulsed laser beam to an object to be sampled and confocally deflecting back-reflected light from the object to the detector, a patient interface, through which the pulsed laser beam is directed, the patient interface having, a cup with a large and small opening, and a notched ring inside the cup; and a controller operatively coupled to the laser source, the imaging system and the shared optics, the controller configured to align the eye for procedure.Type: ApplicationFiled: April 26, 2016Publication date: August 18, 2016Inventors: John S. Hart, David A. Dewey, Georg Schuele, Phillip H. Gooding, Christine J. Beltran, Javier G. Gonzalez, Katrina B. Sheehy, Jeffrey A. Golda, Raymond Woo, Madeleine C. O'Meara, Noah Bareket, Thomas Z. Teisseyre, Bruce Woodley
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Publication number: 20160175146Abstract: A laser eye surgery system that has a patient interface between the eye and the laser system relying on suction to hold the interface to the eye, the patient interface using liquid used as a transmission medium for the laser. During a laser procedure sensors monitor the level of liquid within the patient interface and send a signal to control electronics if the level drops below a threshold value. The sensor may be mounted on the inside of the patient interface, within a fluid chamber. Alternatively, a gas flow meter may be added to a suction circuit for the patient interface that detects abnormal suction levels indicating low fluid level.Type: ApplicationFiled: December 16, 2015Publication date: June 23, 2016Inventors: Phillip H. Gooding, Christine J. Beltran, Brent Eikanas, Michael A. Campos
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Publication number: 20100166747Abstract: The present invention provides, in part, methods for treating a tumor in a human subject comprising inhibiting IGF-1 receptor signaling, methods of determining whether a tumor is more or less likely to respond to such treatment, and compositions for practicing such methods. In particular embodiments, the invention provides fully human, humanized, or chimeric anti-IGF-1R antibodies that bind human IGF-1R, IGF-1R-binding fragments and derivatives of such antibodies, and IGF-1R-binding polypeptides comprising such fragments. Other embodiments provide nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods of making such antibodies, antibody fragments and derivatives and polypeptides, and methods of using such antibodies, antibody fragments and derivatives and polypeptides, including methods of treating or diagnosing subjects having IGF-1R-related disorders or conditions.Type: ApplicationFiled: February 29, 2008Publication date: July 1, 2010Inventors: Pedro J. Beltran, Frank J. Calzone, Gregory Friberg, Christopher Haqq, Anthony W. Tolcher
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Publication number: 20060135369Abstract: The present invention generally relates to methods to reverse ethylene inhibitor responses in plants and plant materials, and particularly relates to methods to reverse various ethylene responses including plant maturation and degradation in plants and plant materials previously exposed to cyclopropene derivatives and compositions thereof.Type: ApplicationFiled: December 17, 2004Publication date: June 22, 2006Inventor: J. Beltran
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Patent number: 6745529Abstract: A pole anchor installation having an anchor base with a central threaded open-ended hole mounted in a receptacle formed in a planking or concrete of a deck. An elongated sleeve having external threads is threadably fitted into the threaded opening of the anchor base so that the sleeve upwardly projects to insertably receive a substantial portion of a pole intended to be supported. A threaded blockage plug is received in the threaded opening of the anchor base when the sleeve and pole are not employed preventing clogging of the threaded opening. In a wood foundation, angular threaded bores are provided into which mounting screws are placed to secure the anchor base. In a concrete block or cement slab, reinforcing rods are carried on the underside of the anchor base and are embedded within the material of the block or slab. In either type of installation, the top surface of the support anchor base is flush with the surrounding surface of either the wood planking or the cement block or cement slab.Type: GrantFiled: January 11, 2002Date of Patent: June 8, 2004Inventor: Juan J. Beltran
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Publication number: 20020062620Abstract: A pole anchor installation having an anchor base with a central threaded open-ended hole mounted in a receptacle formed in a planking or concrete of a deck. An elongated sleeve having external threads is threadably fitted into the threaded opening of the anchor base so that the sleeve upwardly projects to insertably receive a substantial portion of a pole intended to be supported. A threaded blockage plug is received in the threaded opening of the anchor base when the sleeve and pole are not employed preventing clogging of the threaded opening. In a wood foundation, angular threaded bores are provided into which mounting screws are placed to secure the anchor base. In a concrete block or cement slab, reinforcing rods are carried on the underside of the anchor base and are embedded within the material of the block or slab. In either type of installation, the top surface of the support anchor base is flush with the surrounding surface of either the wood planking or the cement block or cement slab.Type: ApplicationFiled: January 11, 2002Publication date: May 30, 2002Inventor: Juan J. Beltran
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Patent number: 4616790Abstract: A tubing retainer for use in fluid or gas delivery system for releasably retaining excess tubing in the system. A member is provided for receiving coils of the excess tubing and a hole and slot arrangement are provided for releasably receiving opposite ends of the excess tubing. The coil receiving member is provided to restrict the minimum diameter of the coils so as to avoid the creation of tube occluding type kinks in the tubing.Type: GrantFiled: July 26, 1984Date of Patent: October 14, 1986Inventor: Delfin J. Beltran