Patents by Inventor J. Breitenbucher

J. Breitenbucher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HETEROCYCLIC AMIDES AS MODULATORS OF TRPA1
    Publication number: 20120083474
    Abstract: Certain heterocyclic amide compounds are described. The compounds may be used in pharmaceutical compositions and methods for treating disease states, disorders, and conditions mediated by TRPA1 activity, such as pain, arthritis, itch, cough, asthma, or inflammatory bowel disease.
    Type: Application
    Filed: June 4, 2010
    Publication date: April 5, 2012
    Inventors: Didier Jean-Claude Berthelot, Henricus Jacobus Maria Gijsen, Mirko Zaja, Jason Rech, Alec Lebsack, Wei Xiao, Bryan Branstetter, Guy J. Breitenbucher
  • Substituted Benzimidazoles and Imidazo-[4,5]-Pyridines
    Publication number: 20080009493
    Abstract: 2-Aryl substituted benzimidazoles and imidazo[4,5]pyridines are disclosed as inhibitors of Cds1 and useful as adjuvants to chemotherapy or radiation therapy in the treatment of cancer.
    Type: Application
    Filed: August 2, 2007
    Publication date: January 10, 2008
    Inventors: Kristen Arienti, Frank Axe, J. Breitenbucher, Liming Huang, Alice Lee, Kelly McClure
  • CCK-1 Receptor Modulators
    Publication number: 20070249698
    Abstract: Certain imidazole compounds are CCK1 modulators useful in the treatment of CCK1 mediated diseases.
    Type: Application
    Filed: July 3, 2007
    Publication date: October 25, 2007
    Inventors: J. Breitenbucher, Michael Hack, Clark Sehon
  • Method for treating allergies using substituted pyrazoles
    Publication number: 20070105841
    Abstract: A method for treating an allergic condition, including an atopic allergic condition, using substituted pyrazoles.
    Type: Application
    Filed: October 31, 2006
    Publication date: May 10, 2007
    Inventors: J. Breitenbucher, Hui Cai, James Edwards, Cheryl Grice, Yin Gu, Darin Gustin, Lars Karlsson, Haripada Khatuya, Steven Meduna, Barbara Pio, Siquan Sun, Kevin Tays, Robin Thurmond, Jianmei Wei
  • Substituted pyrazoles
    Publication number: 20070021437
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
    Type: Application
    Filed: September 7, 2006
    Publication date: January 25, 2007
    Inventors: Mary Beavers, J. Breitenbucher, Hui Cai, James Edwards, Cheryl Grice, Darin Gustin, Haripada Khatuya, Steven Meduna, Barbara Pio, Kevin Tays, Jianmei Wei
  • Substituted pyrazoles
    Publication number: 20070010530
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
    Type: Application
    Filed: September 7, 2006
    Publication date: January 11, 2007
    Inventors: Mary Beavers, J. Breitenbucher, Hui Cai, James Edwards, Cheryl Grice, Darin Gustin, Haripada Khatuya, Steven Meduna, Barbara Pio, Kevin Tays, Jianmei Wei
  • Substituted pyrazoles
    Publication number: 20070004754
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
    Type: Application
    Filed: September 7, 2006
    Publication date: January 4, 2007
    Inventors: Mary Beavers, J. Breitenbucher, Hui Cai, James Edwards, Cheryl Grice, Darin Gustin, Haripada Khatuya, Steven Meduna, Barbara Pio, Kevin Tays, Jianmei Wei
  • N-heteroarylpiperazinyl ureas as modulators of fatty acid amide hydrolase
    Publication number: 20070004741
    Abstract: Certain N-heteroarylpiperazinyl urea compounds are described, which are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity. Thus, the compounds may be administered to treat, e.g., anxiety, pain, inflammation, sleep disorders, eating disorders, or movement disorders (such as multiple sclerosis).
    Type: Application
    Filed: June 28, 2006
    Publication date: January 4, 2007
    Inventors: Richard Apodaca, J. Breitenbucher, Kanaka Pattabiraman, Mark Seierstad, Wei Xiao
  • Substituted pyrazoles
    Publication number: 20070004738
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
    Type: Application
    Filed: September 7, 2006
    Publication date: January 4, 2007
    Inventors: Mary Beavers, J. Breitenbucher, Hui Cai, James Edwards, Cheryl Grice, Darin Gustin, Haripada Khatuya, Steven Meduna, Barbara Pio, Kevin Tays, Jianmei Wei
  • Substituted pyrazoles
    Publication number: 20070004747
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
    Type: Application
    Filed: September 7, 2006
    Publication date: January 4, 2007
    Inventors: Mary Beavers, J. Breitenbucher, Hui Cai, James Edwards, Cheryl Grice, Darin Gustin, Haripada Khatuya, Steven Meduna, Barbara Pio, Kevin Tays, Jianmei Wei
  • Substituted pyrazoles
    Publication number: 20070004755
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
    Type: Application
    Filed: September 7, 2006
    Publication date: January 4, 2007
    Inventors: Mary Beavers, J. Breitenbucher, Hui Cai, James Edwards, Cheryl Grice, Darin Gustin, Haripada Khatuya, Steven Meduna, Barbara Pio, Kevin Tays, Jianmei Wei
  • Substituted benzimidazoles and imidazo-[4,5]-pyridines
    Publication number: 20060252793
    Abstract: 2-Aryl substituted benzimidazoles and imidazo[4,5]pyridines are disclosed as inhibitors of Cds1 and useful as adjuvants to chemotherapy or radiation therapy in the treatment of cancer.
    Type: Application
    Filed: June 30, 2006
    Publication date: November 9, 2006
    Inventors: Michael Ameriks, Kristen Arienti, Frank Axe, J. Breitenbucher
  • Piperazinyl and piperidinyl ureas as modulators of fatty acid amide hydrolase
    Publication number: 20060173184
    Abstract: Certain piperazinyl and piperidinyl urea compounds are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity. Thus, the compounds may be administered to treat, e.g., anxiety, pain, inflammation, sleep disorders, eating disorders, or movement disorders (such as multiple sclerosis).
    Type: Application
    Filed: December 29, 2005
    Publication date: August 3, 2006
    Inventors: Richard Apodaca, J. Breitenbucher, Kanaka Pattabiraman, Mark Seierstad, Wei Xiao
  • CCK-1 receptor modulators
    Publication number: 20060014817
    Abstract: There are provided by the present invention certain pyrazole based CCK-1 receptor modulators.
    Type: Application
    Filed: September 19, 2005
    Publication date: January 19, 2006
    Inventors: Terrance Barrett, J. Breitenbucher, Laurent Gomez, Michael Hack, Liming Huang, Kelly McClure, Magda Morton, Clark Sehon, Nigel Shankley
  • Aryl-substituted benzimidazole and imidazopyridine ethers
    Publication number: 20060004039
    Abstract: Aryl substituted benzimidazole and imidazo[4,5]pyridine ethers are described as inhibitors of Cds1 and useful as adjuvants to chemotherapy or radiation therapy in the treatment of cancer.
    Type: Application
    Filed: June 27, 2005
    Publication date: January 5, 2006
    Inventors: J. Breitenbucher, Alice Lee-Dutra, Danielle Neff
  • CCK-1 receptor modulators
    Publication number: 20050197377
    Abstract: Certain imidazole compounds are CCK1 modulators useful in the treatment of CCK1 mediated diseases.
    Type: Application
    Filed: December 21, 2004
    Publication date: September 8, 2005
    Inventors: J. Breitenbucher, Michael Hack, Clark Sehon
  • Phenyl-substituted imidazopyridines
    Publication number: 20050090523
    Abstract: The invention features pharmaceutically-active imidazopyridines and derivatives that are substituted with phenyl, methods of making them, and methods of using them.
    Type: Application
    Filed: October 7, 2004
    Publication date: April 28, 2005
    Inventors: J. Breitenbucher, Nicholas Carruthers, Xiaobing Li, Laura McAtee, Chandravadan Shah, Ronald Wolin
  • Phenyl-substituted imidazopyridines
    Publication number: 20050085502
    Abstract: The invention features pharmaceutically-active imidazopyridines and derivatives that are substituted with phenyl, methods of making them, and methods of using them.
    Type: Application
    Filed: October 7, 2004
    Publication date: April 21, 2005
    Inventors: J. Breitenbucher, Nicholas Carruthers, Xiaobing Li, Laura McAtee, Chandravadan Shah, Ronald Wolin
  • Phenyl-substituted imidazopyridines
    Publication number: 20050085501
    Abstract: The invention features pharmaceutically-active imidazopyridines and derivatives that are substituted with phenyl, methods of making them, and methods of using them.
    Type: Application
    Filed: October 7, 2004
    Publication date: April 21, 2005
    Inventors: J. Breitenbucher, Nicholas Carruthers, Xiaobing Li, Laura McAtee, Chandravadan Shah, Ronald Wolin
  • Benzoimidazole compounds
    Publication number: 20050070550
    Abstract: Benzoimidazole compounds, compositions, and methods of using them in leukocyte recruitment inhibition, in modulating H4 receptor, and in treating conditions such as inflammation, H4 receptor-mediated conditions, and related conditions.
    Type: Application
    Filed: September 29, 2004
    Publication date: March 31, 2005
    Inventors: Kristen Arienti, J. Breitenbucher, Daniel Buzard, James Edwards, Michael Hack, Haripada Khatuya, David Kindrachuk, Alice Lee, Jennifer Venable