Patents by Inventor J. Bruce Smith

J. Bruce Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6472225
    Abstract: A method of treating autoimmune diseases is provided which involves administering an effective amount of allogeneic mononuclear cells or a molecule derived from these cells to an individual suffering from an autoimmune disease. Also provided are compositions for the treatment of autoimmune diseases.
    Type: Grant
    Filed: February 18, 2000
    Date of Patent: October 29, 2002
    Assignee: Thomas Jefferson University
    Inventors: J. Bruce Smith, John G. Fort
  • Patent number: 6033661
    Abstract: A method of treating autoimmune diseases is provided which involves administering an effective amount of allogeneic mononuclear cells or a molecule derived from these cells to an individual suffering from an autoimmune disease. Also provided are compositions for the treatment of autoimmune diseases.
    Type: Grant
    Filed: June 24, 1997
    Date of Patent: March 7, 2000
    Assignee: Thomas Jefferson University
    Inventors: J. Bruce Smith, John G. Fort
  • Patent number: 5750339
    Abstract: The invention features a method of distinguishing fetal cells from maternal cells in a sample. The method comprises the steps of contacting a sample comprising fetal cells and maternal cells with a probe which is complementary to HLA-G mRNA and identifying individual cells in which the probe hybridize to mRNA in the cells. The absence of hybridization indicates that the cells are maternal cells. The presence of hybridization indicates that the cells are fetal cells. Fetal cells identified in accordance with the invention may be tested for genetic abnormalities.
    Type: Grant
    Filed: November 30, 1994
    Date of Patent: May 12, 1998
    Assignee: Thomas Jefferson University
    Inventor: J. Bruce Smith
  • Patent number: 5723503
    Abstract: A method of treating rheumatoid arthritis is provided which involves administering an effective amount of allogeneic mononuclear cells or a molecule derived from these cells to an individual having rheumatoid arthritis. Also provided are compositions for the treatment of rheumatoid arthritis.
    Type: Grant
    Filed: September 28, 1994
    Date of Patent: March 3, 1998
    Assignee: Thomas Jefferson University
    Inventors: J. Bruce Smith, John G. Fort
  • Patent number: 5674487
    Abstract: A method of treating autoimmune diseases is provided which involves administering an effective amount of allogeneic mononuclear cells or a molecule derived from these cells to an individual suffering from an autoimmune disease. Also provided are compositions for the treatment of autoimmune diseases.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: October 7, 1997
    Inventors: J. Bruce Smith, John G. Fort