Patents by Inventor J. Claiborne Stephens

J. Claiborne Stephens has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7058517
    Abstract: Methods, computer program(s) and database(s) to analyze and make use of gene haplotype information. These include methods, program, and database to find and measure the frequency of haplotypes in the general population; methods, program, and database to find correlation's between an individual's haplotypes or genotypes and a clinical outcome; methods, program, and database to predict an individual's haplotypes from the individual's genotype for a gene; and methods, program, and database to predict an individual's clinical response to a treatment based on the individual's genotype or haplotype.
    Type: Grant
    Filed: June 26, 2000
    Date of Patent: June 6, 2006
    Assignee: Genaissance Pharmaceuticals, Inc.
    Inventors: R. Rex Denton, Richard S. Judson, Gualberto RuaƱo, J. Claiborne Stephens, Andreas K. Windemuth, Chuanbo Xu
  • Patent number: 6931326
    Abstract: Methods, computer program(s) and database(s) to analyze and make use of gene haplotype information. These include methods, program, and database to find and measure the frequency of haplotypes in the general population; methods, program, and database to find correlation's between an individual's haplotypes or genotypes and a clinical outcome; methods, program, and database to predict an individual's haplotypes from the individual's genotype for a gene; and methods, program, and database to predict an individual's clinical response to a treatment based on the individual's genotype or haplotype.
    Type: Grant
    Filed: December 21, 2001
    Date of Patent: August 16, 2005
    Assignee: Genaissance Pharmaceuticals, Inc.
    Inventors: Richard S. Judson, J. Claiborne Stephens, Andreas K. Windemuth
  • Publication number: 20030211501
    Abstract: Methods, computer programs and databases for determining haplotypes from a collection of polymorphisms are provided. These include methods, programs, and databases to find and measure the frequency of haplotypes in the general population; and methods, programs, and databases for predicting an individual's haplotypes from the individual's genotype for a gene.
    Type: Application
    Filed: October 18, 2002
    Publication date: November 13, 2003
    Inventors: J. Claiborne Stephens, Andreas Windemuth
  • Publication number: 20030175710
    Abstract: Novel genetic variants of the Tumor Necrosis Factor Receptor Superfamily, Member 11b (Osteoprotegerin) (TNFRSF11B) gene are described. Various genotypes, haplotypes, and haplotype pairs that exist in the general United States population are disclosed for the TNFRSF11B gene. Compositions and methods for haplotyping and/or genotyping the TNFRSF11B gene in an individual are also disclosed. Polynucleotides defined by the haplotypes disclosed herein are also described.
    Type: Application
    Filed: January 9, 2002
    Publication date: September 18, 2003
    Inventors: Anne Chew, R. Rex Denton, Karyn M. Bieglecki, Krishnan Nandabalan, J. Claiborne Stephens
  • Publication number: 20030165844
    Abstract: Novel genetic variants of the Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) gene are described. Various genotypes, haplotypes, and haplotype pairs that exist in the general United States population are disclosed for the TNFRSF1A gene. Compositions and methods for haplotyping and/or genotyping the TNFRSF1A gene in an individual are also disclosed. Polynucleotides defined by the haplotypes disclosed herein are also described.
    Type: Application
    Filed: August 31, 2001
    Publication date: September 4, 2003
    Applicant: Genaissance Pharmaceuticals, Inc.
    Inventors: Alison E. Anastasio, Anne Chew, R. Rex Denton, Krishnan Nandabalan, Katie E. Parks, J. Claiborne Stephens
  • Patent number: 6586183
    Abstract: Genotypes and haplotypes for thirteen polymorphic sites in the &bgr;2-adrenergic receptor (&bgr;2AR) gene are disclosed. Compositions and methods for predicting genetic predisposition to disease associated with polymorphic sites in the (&bgr;2AR) gene, as well as for predicting response to &bgr;-agonists, are also disclosed.
    Type: Grant
    Filed: March 16, 2001
    Date of Patent: July 1, 2003
    Assignee: Genaissance Pharmaceuticals, Inc.
    Inventors: Connie M. Drysdale, Richard S. Judson, Stephen B. Liggett, Krishnan Nandabalan, Catherine B. Stack, J. Claiborne Stephens
  • Publication number: 20030091998
    Abstract: Genotypes and haplotypes for thirteen polymorphic sites in the &bgr;2-adrenergic receptor (&bgr;2AR) gene are disclosed. Compositions and methods for predicting genetic predisposition to disease associated with polymorphic sites in the (&bgr;2AR) gene, as well as for predicting response to &bgr;-agonists, are also disclosed.
    Type: Application
    Filed: March 16, 2001
    Publication date: May 15, 2003
    Inventors: Connie M. Drysdale, Richard S. Judson, Stephen B. Liggett, Krishnan Nandabalan, J. Claiborne Stephens
  • Publication number: 20030039979
    Abstract: Genotypes and haplotypes for thirteen polymorphic sites in the &bgr;2-adrenergic receptor (&bgr;2AR) gene are disclosed. Compositions and methods for predicting genetic predisposition to disease associated with polymorphic sites in the (&bgr;2AR) gene, as well as for predicting response to &bgr;-agonists, are also disclosed.
    Type: Application
    Filed: September 12, 2001
    Publication date: February 27, 2003
    Inventors: Stephen B. Liggett, Connie M. Drysdale, J. Claiborne Stephens, Krishnan Nandabalan, Richard S. Judson, Catherine M. Stack
  • Publication number: 20010051712
    Abstract: Genotypes and haplotypes for thirteen polymorphic sites in the &bgr;2-adrenergic receptor (&bgr;2AR) gene are disclosed. Compositions and methods for predicting genetic predisposition to disease associated with polymorphic sites in the (&bgr;2AR) gene, as well as for predicting response to &bgr;-agonists, are also disclosed.
    Type: Application
    Filed: March 16, 2001
    Publication date: December 13, 2001
    Inventors: Connie M. Drysdale, Richard S. Judson, Stephen B. Liggett, Krishnan Nandabalan, Catherine B. Stack, J. Claiborne Stephens