Abstract: A system and method are described in which a document transaction management platform coordinates performance of trust actions across a plurality of trust service providers. For example, a method can include operations executing on a connector module in communication with a digital transaction management platform and a trust service provider, such as the following. Receiving, from the digital transaction management platform, a transaction request including a token and a requested trust action. Accessing user information for a recipient involved in the requested trust action using the token. Obtaining, from the digital transaction management platform, transaction data associated with the requested trust action. Coordinating, with the trust service provider, performance of the trust action on at least a portion of the transaction data. Transmitting, to the digital transaction management platform, a proof received from the trust service provider confirming performance of the trust action.

Abstract: This document provides methods and materials involved in treating cancer. For example, methods and materials for using chimeric antigen receptor T cells having reduced expression levels of a tumor necrosis factor receptor 2 (TNFR2) polypeptide in an adoptive cell therapy (e.g., a chimeric antigen receptor (CAR) T cell therapy) to treat a mammal (e.g., a human) having cancer are provided.

Abstract: A method for designing and operating aircraft nose landing gear wheel-mounted electric taxi systems to move aircraft during ground travel. Electric taxi system components are engineered and sized to produce optimal ground travel torque to move aircraft during the majority of aircraft ground travel and are operated in conjunction with the aircraft steering to turn the nose wheels to an effective angle that moves the aircraft during pushback and in breakaway situations. The nose landing gear wheels are turned to an effective angle and the electric taxi systems are operated simultaneously to get the aircraft moving. After breaking away, the aircraft is driven with electric taxi systems at the optimal ground travel torque in a forward or reverse direction with the nose wheels parallel or in a desired ground travel direction with the nose wheels steered in the desired direction of ground travel.

Abstract: A device and method for intravascular treatment of an embolism, and particularly a pulmonary embolism, is disclosed herein. One aspect of the present technology, for example, is directed toward a clot treatment device that includes a support member having a plurality of first clot engagement members and second clot engagement members positioned about the circumference of a distal portion of the support member. In an undeployed state, individual first clot engagement members can be linear and have a first length, and individual second clot engagement members can be linear and have a second length that is less than the first length. The clot engagement members can be configured to penetrate clot material along an arcuate path and hold clot material to the clot treatment device.

Abstract: Systems and methods for removal of thrombus from a blood vessel in a body of a patient are disclosed herein. The method can include: providing a thrombus extraction device including a proximal self-expanding member formed of a unitary fenestrated structure, a distal substantially cylindrical portion formed of a net-like filament mesh structure, and an inner shaft member connected to a distal end of the net-like filament mesh structure; advancing a catheter constraining the thrombus extraction device through a vascular thrombus, deploying the thrombus extraction; retracting the thrombus extraction device to separate a portion of the thrombus from the vessel wall and to capture the portion of the thrombus within the net-like filament mesh structure; and withdrawing the thrombus extraction device from the body to remove thrombus from the patient.

Abstract: Frozen un-proofed dough pieces are produced by cutting a dough sheet into strips and producing a score through an upper skin of each strip with at least one blunt deformation tool prior to freezing. The un-proofed dough pieces are formed by mass production, with an un-proofed dough sheet being cut to form dough strips which are then cut into the un-proofed dough pieces, with the score for each un-proofed dough piece being formed by pressing the upper skin of the dough down into the body of the dough, thereby deforming and pre-stressing the dough to create weak zones, either before, during or after the individual un-proofed dough pieces are actually created, but before freezing. Upon heating, openings are established in the upper skin along score lines.

Abstract: Methods and devices for treatment of a patient's cerebral aneurysm is described. The device includes a permeable shell having a radially constrained elongated state configured for delivery within a catheter lumen, an expanded state with a longitudinally shortened configuration relative to the radially constrained state, and a plurality of elongate filaments that are woven together to form a mesh. The proximal ends of each of the plurality of filaments are gathered by a proximal hub and the distal ends of each of the plurality of filaments are gathered by a distal hub. The proximal portion of the permeable shell includes a swellable polymer. The method includes advancing the implant in a microcatheter to a region of interest in the cerebral vasculature, deploying the implant within the cerebral aneurysm, and withdrawing the microcatheter from the region of interest after deploying the implant.

Abstract: An estimation of junction temperatures of transistors in power electronics converter.

Abstract: The disclosure relates to estimation of junction temperatures of transistors in a power electronics converter. Example embodiments include a method of estimating a junction temperature of a transistor in a power electronics converter configured to convert between first and second supply voltages, the method comprising: providing a gate switching signal to the transistor; measuring a rate of change of current through the converter during a switching period of the transistor; and outputting an estimated junction temperature of the transistor based on the measured rate of change of current, wherein the rate of change of current is measured while a gate voltage of the transistor is above a gate threshold voltage and a drain-source voltage across the transistor is above a predetermined fraction of the first or second supply voltage whereby the rate of change of current is measured in a linear region.

Abstract: This document provides methods and materials involved in treating cancer. For example, chimeric antigen receptor T cells having reduced levels of GM-CSF are provided. Also provided as methods for making and using chimeric antigen receptor T cells having reduced levels of GM-CSF.

Abstract: A method includes receiving a first transaction request and a second transaction request including identification of a first trust action and a second trust action requested to be performed with respect to an electronic document. A first trust service provider and a second trust service provider, different from the first trust service provider, are selected to perform the requested first trust action and the second trust action, respectively. Performance of the first trust action and the second trust action on the same electronic document is coordinated with the selected first trust service provider and the second trust action provider. A first proof and a second proof are obtained confirming performance of the requested first trust action and the requested second trust action by the respective trust service providers.

Abstract: Methods of braiding using a braiding mechanism are described. The braiding mechanism includes a disc defining a plane and a circumferential edge, a mandrel extending from a center of the disc that is adapted to hold a plurality of filaments extending radially from the mandrel toward the circumferential edge of the disc, a plurality of catch mechanisms positioned circumferentially around the edge of the disc, a plurality of actuators adapted to move the plurality of catch mechanisms in a substantially radial direction relative to the circumferential edge of the disc, and a plurality of filaments extending radially from the mandrel towards circumferential edge of the disc. A middle portion of each filament of the plurality of filaments contacts an end of the mandrel.

Abstract: A device and method for intravascular treatment of an embolism, and particularly a pulmonary embolism, is disclosed herein. One aspect of the present technology, for example, is directed toward a clot treatment device that includes a support member having a plurality of first clot engagement members and second clot engagement members positioned about the circumference of a distal portion of the support member. In an undeployed state, individual first clot engagement members can be linear and have a first length, and individual second clot engagement members can be linear and have a second length that is less than the first length. The clot engagement members can be configured to penetrate clot material along an arcuate path and hold clot material to the clot treatment device.

Abstract: Implementations of the present disclosure include receiving transaction data for a transaction that is to be executed by a computer-implemented person-to-person (P2P) payment system, the transaction data including a unique account identifier uniquely identifying an account of a first user among a plurality of accounts of the first user, and an amount to be transferred to the account from a second user, processing the transaction data to execute the transaction, and transmitting notifications to each of the first user and the second user, the notifications providing information regarding the transaction.

Abstract: A computer-implemented automated monitoring and behavioral health treatment recommendation method comprising: receiving a set of data from a patient sensor and a set of data from a caregiver for a patient; computing, via a processor, an behavioral health dosage for the patient; correlating, via a processor, the behavioral health dosage to a corpus of behavioral health dosage treatment data; and calibrating the behavioral health dosage, via processor; in light of a cohort of similar patient behavioral health dosages and; measuring a progress metric towards a set treatment goal of the patient, via the processor.

Abstract: Systems and methods for removal of thrombus from a blood vessel in a body of a patient are disclosed herein. The method can include: providing a thrombus extraction device including a proximal self-expanding member formed of a unitary fenestrated structure, a distal substantially cylindrical portion formed of a net-like filament mesh structure, and an inner shaft member connected to a distal end of the net-like filament mesh structure; advancing a catheter constraining the thrombus extraction device through a vascular thrombus, deploying the thrombus extraction; retracting the thrombus extraction device to separate a portion of the thrombus from the vessel wall and to capture the portion of the thrombus within the net-like filament mesh structure; and withdrawing the thrombus extraction device from the body to remove thrombus from the patient.

Abstract: Systems and methods for removal of thrombus from a blood vessel in a body of a patient are disclosed herein. The method can include: providing a thrombus extraction device including a proximal self-expanding member formed of a unitary fenestrated structure, a distal substantially cylindrical portion formed of a net-like filament mesh structure, and an inner shaft member connected to a distal end of the net-like filament mesh structure; advancing a catheter constraining the thrombus extraction device through a vascular thrombus, deploying the thrombus extraction; retracting the thrombus extraction device to separate a portion of the thrombus from the vessel wall and to capture the portion of the thrombus within the net-like filament mesh structure; and withdrawing the thrombus extraction device from the body to remove thrombus from the patient.

Abstract: A system and a method are provided for safely and efficiently transferring cargo and freight packed in ULD containers directly between an airport freight terminal and freight aircraft. An enclosed freightway is designed to provide a direct connection between the freight terminal and aircraft cargo doors. The enclosed freightway is structured and sized to move ULD containers automatically or manually between freight aircraft and freight terminals. Different freightway configurations enable direct connection between the freight terminal and freight aircraft main cargo door when freight aircraft are driven by electric taxi drive systems or aircraft engines and parked in nose-in orientations and when freight aircraft are driven by electric taxi drive systems and parked in parallel orientations at the freight terminal. An alternative embodiment provides direct connections between freight aircraft cargo doors and interior loading docks for aircraft driven with electric taxi drive systems.

Abstract: Methods of braiding using a braiding mechanism are described. The braiding mechanism includes a disc defining a plane and a circumferential edge, a mandrel extending from a center of the disc that is adapted to hold a plurality of filaments extending radially from the mandrel toward the circumferential edge of the disc, a plurality of catch mechanisms positioned circumferentially around the edge of the disc, a plurality of actuators adapted to move the plurality of catch mechanisms in a substantially radial direction relative to the circumferential edge of the disc, and a plurality of filaments extending radially from the mandrel towards circumferential edge of the disc. A middle portion of each filament of the plurality of filaments contacts an end of the mandrel.

Abstract: A monitoring system and method are provided to monitor ground movement of aircraft driven with electric taxi drive systems and movement of ground service vehicles and equipment and personnel within airport ramp areas. Monitor and sensor devices, including those that are intelligent and employ scanning technology to generate image, positional, and other data may be mounted in locations on aircraft, ground service vehicles and equipment, passenger loading bridges, an airport terminal, and other ramp locations to generate a constant stream of data as the aircraft moves into, within, and out of an airport ramp area. The data stream is transmitted to an artificial intelligence-based processing system to identify and communicate possible safety hazards to multiple locations so that the aircraft's ground travel or a ground vehicle's travel may be altered to avoid identified safety hazards and to avoid collisions.