Abstract: The disclosure includes a method, comprising passing a fluid into a co-current contactor, passing a solvent into the co-current contactor, dividing the solvent into solvent droplets having a first average droplet size, placing the fluid in contact with the solvent droplets to create a combined stream, coalescing at least a portion of the solvent droplets to create solvent droplets having a second average droplet size, wherein the second average droplet size is greater than the first average droplet size, and separating the fluid and the solvent.

Abstract: Provided herein are peptidomimetic macrocycles containing amino acid sequences with at least two modified amino acids that form an intramolecular cross-link that can help to stabilize a secondary structure of the amino acid sequence. Suitable sequences for stabilization include those with homology to the p53 protein. These sequences can bind to the MDM2 and/or MDMX proteins. Also provided herein are methods of using such macrocycles for the treatment of diseases and disorders, such as cancers or other disorders characterized by a low level or low activity of a p53 protein or high level of activity of a MDM2 and/or MDMX protein.

Abstract: A computer-implemented method for gathering user-related tax data for use with tax preparation software includes a computing device executing a data capture utility configured to connect to one or more remotely located data sources, wherein the data capture utility captures user-specific tax data from the one or more remotely located data sources and stores the captured data in a data store. The computing device executes a tax logic engine configured to read data from the data store and determine the completeness of the data contained within the data store. The computing device communicates a message to the user regarding the level of completeness of the data contained within the data store.

Abstract: The disclosure includes a method, comprising passing a fluid into a co-current contactor, passing a solvent into the co-current contactor, dividing the solvent into solvent droplets having a first average droplet size, placing the fluid in contact with the solvent droplets to create a combined stream, coalescing at least a portion of the solvent droplets to create solvent droplets having a second average droplet size, wherein the second average droplet size is greater than the first average droplet size, and separating the fluid and the solvent.

Abstract: The disclosed embodiments provide a system that facilitates application usage. During operation, the system obtains a user context associated with a first user, wherein the user context includes at least one of a location of the first user, profile data for the first user, device data associated with a computing device for the first user, and data types associated with existing applications on the computing device. Next, the system obtains a first set of new applications matching the user context. Finally, the system provides the first set of new applications to the first user for installation and use by the first user.

Abstract: The disclosure includes a method, comprising passing a fluid into a co-current contactor, passing a solvent into the co-current contactor, dividing the solvent into solvent droplets having a first average droplet size, placing the fluid in contact with the solvent droplets to create a combined stream, coalescing at least a portion of the solvent droplets to create solvent droplets having a second average droplet size, wherein the second average droplet size is greater than the first average droplet size, and separating the fluid and the solvent.

Abstract: A method for decontaminating a contaminated fluid stream, comprising receiving the contaminated fluid stream, distributing the contaminated fluid stream substantially equally across a plurality of separation units sharing a unitary pressure boundary, receiving a solvent stream, and co-currently contacting the contaminated fluid stream with the solvent stream in the plurality of separation units.

Abstract: A computer-implemented method for gathering user-related tax data for use with tax preparation software includes a computing device executing a data capture utility configured to connect to one or more remotely located data sources, wherein the data capture utility captures user-specific tax data from the one or more remotely located data sources and stores the captured data in a data store. The computing device executes a tax logic engine configured to read data from the data store and determine the completeness of the data contained within the data store. The computing device communicates a message to the user regarding the level of completeness of the data contained within the data store.

Abstract: Provided herein are peptidomimetic macrocycles containing amino acid sequences with at least two modified amino acids that form an intramolecular cross-link that can help to stabilize a secondary structure of the amino acid sequence. Suitable sequences for stabilization include those with homology to the p53 protein. These sequences can bind to the MDM2 and/or MDMX proteins. Also provided herein are methods of using such macrocycles for the treatment of diseases and disorders, such as cancers or other disorders characterized by a low level or low activity of a p53 protein or high level of activity of a MDM2 and/or MDMX protein.

Abstract: A fractionation system for removing heavy hydrocarbons in a gas stream. A stripping section receives a predominantly liquid phase of the feed gas stream. A co-current contacting system receives a predominantly vapor phase of the feed gas stream. The co-current contacting system includes a compact contacting bundle disposed within a vessel and including a plurality of substantially parallel contacting units, each of the plurality of contacting units having a droplet generator, a mass transfer section, and a separation system. Each droplet generator generates droplets from a liquid disperses the droplets into a gas stream. Each mass transfer section provides a mixed, two-phase flow having a vapor phase and a liquid phase. Each separation system separates the vapor phase from the liquid phase such that the concentration of heavy hydrocarbons in the vapor phase is lower than in the liquid phase.

Abstract: A fractionation system for removing heavy hydrocarbons in a gas stream. A stripping section receives a predominantly liquid phase of a feed gas stream. First and second co-current contacting systems are located in-line within a pipe. The first co-current contacting system receives a predominantly vapor phase of the feed gas stream. Each co-current contacting system includes a co-current contactor and a separation system. Each co-current contactor includes a droplet generator and a mass transfer section. The droplet generator generates droplets from a liquid and disperses the droplets into a gas stream. The mass transfer section provides a mixed, two-phase flow having a vapor phase and a liquid phase. The separation system separates the vapor phase from the liquid phase.

Abstract: A vertically oriented co-current contacting system and methods for separating impurities from a gas stream including a vertically oriented co-current contactor (VOCC) located in-line within a pipe, a vertically oriented mixer (VOM) including an annular support ring configured to maintain the VOM within the pipe, a number of radial blades configured to allow a liquid stream to flow into the VOM, and a central gas entry cone configured to allow a gas stream to flow through a hollow section within the VOM, a vertically oriented mass transfer section downstream of the VOM. The VOM and the vertically oriented mass transfer section provide for efficient incorporation of liquid droplets including impurities from the gas stream formed from the liquid stream into the gas stream. The vertically oriented co-current contacting system also includes a separation system configured to remove the liquid droplets.

Abstract: A co-current contacting system is described herein. The co-current contacting system includes a co-current contactor located in-line within a pipe. The co-current contactor includes an annular support ring configured to maintain the co-current contactor within the pipe and a number of radial blades configured to allow a liquid stream to flow into the co-current contactor. The co-current contacts also includes a central gas entry cone configured to allow a gas stream to flow through a hollow section within the co-current contactor, wherein the co-current contactor provides for efficient incorporation of liquid droplets formed from the liquid stream into the gas stream. The co-current contacting system also includes a separation system configured to remove the liquid droplets from the gas stream.

Abstract: A method of emulsion extraction and processing from an oil/water separator, comprising detecting an emulsion parameter, passing an emulsion stream out of the separator, combining the emulsion stream with a water stream exiting the separator to create a diluted emulsion, dynamically adjusting a dilution of the diluted emulsion based at least in part on the emulsion parameter, and separating the diluted emulsion into an underflow stream comprising substantially water and a reject stream comprising substantially oil.

Abstract: A method of predicting the strength characteristics of a composite laminate may include loading a structural model of a composite laminate formed of a material system. The method may additionally include comparing strain invariants from loading the composite laminate to critical strain invariant values of the material system. The method may also include identifying as a first significant event (FSE) a strain invariant of the matrix and/or the fibers reaching a critical strain invariant value.

Abstract: An apparatus is disclosed for maintaining constant fluid pressure and equalized fluid flow among a plurality of downcomer lines through which liquid from a tower is directed. A substantially annular fluid distribution belt is disposed at the circumference of the tower. The fluid distribution belt collects liquid from the tower. At least two outlets direct liquid from the fluid distribution belt out of the tower and into a corresponding number of downcomer lines disposed external to the tower.

Abstract: A novel method for retiming a portion of a media content (e.g., audio data, video data, audio and video data, etc.) in a media-editing application is provided. The media editing application includes a user interface for defining a range in order to select a portion of the media content. The media editing application performs retiming by applying a speed effect to the portion of the media content selected by the defined range. For a faster speed effect, the media editing application retimes the selected portion of the media content by sampling the media content at a faster rate. For a slower speed effect, the media editing application retimes the selected portion of the media content by sampling the content at a slower rate.

Abstract: A system for explaining tax questions for an electronic tax return preparation program includes a computing device having a tax logic agent and a user interface controller. The computing device executes the tax logic agent, which analyzes a completeness graph to identify a required variable. The tax logic agent also determines whether an explanation asset is indexed to the required variable in the completeness graph, and sends an identity of the required variable to a user interface controller. The user interface controller generates a tax question corresponding to the required variable. When the tax logic agent determines that an explanation asset is indexed to the required variable in the completeness graph, the computing device presents the tax question and the explanation asset. When an explanation asset is not indexed to the required variable in the completeness graph, the computing device presents the tax question without the explanation asset.

Abstract: A system for explaining added tax questions resulting from modified tax data for an electronic tax return preparation program includes a computing device having a completeness graph engine, an explanation engine, and a user interface controller. The computing device executes the completeness graph engine, which takes a first snapshot of input needs for a completeness graph corresponding to a tax topic, takes a second snapshot of input needs for the completeness graph corresponding to the tax topic after receiving modified tax data, and compares the first and second snapshots to identify an added variable in the completeness graph. An explanation engine analyzes the completeness graph and the modified tax data to generate an explanation asset for the added variable. A user interface controller generates a tax question corresponding to the added variable. The computing device presents the tax question and the explanation asset to a user.

Abstract: Systems and methods are provided for reducing maldistribution of liquids and vapors in packed towers. An exemplary separation system includes a separation tower including at least two packed beds, and a vapor redistribution plate disposed between two sequentially disposed packed beds, wherein the vapor redistribution plate is configured to mix a vapor from a lower packed bed before introducing the vapor into an upper packed bed.