Patents by Inventor J. Gregory Reid

J. Gregory Reid has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENETICALLY MODIFIED ORGANISMS FOR THE PRODUCTION OF STEROID DERIVATIVES
    Publication number: 20240102073
    Abstract: Provided are biosynthetic processes for producing sterol derivatives, and to non-naturally occurring organisms capable of producing sterol derivatives. More specifically, genetically modified non-naturally occurring organisms for producing KCEA, KCDA, and related compounds, from cholesterol, ?-sitosterol, campesterol and their analogs, are provided.
    Type: Application
    Filed: June 8, 2021
    Publication date: March 28, 2024
    Inventors: JAYACHANDRA P. REDDY, J. GREGORY REID, RICHARD REUMERMAN, BERNHARD J. PAUL, URSULA SCHELL
  • ENZYMATIC METHODS FOR CONVERTING LCA AND 3-KCA TO UDCA AND 3-KUDCA
    Publication number: 20230416800
    Abstract: 7?-hydroxylation systems are provided, as well as methods for producing ?P-hydroxy derivatives of lithocholic acid and 3-keto-lithocholic acid from such systems. Also provided are recombinant organisms useful for the production of such enzymatic systems, and to plasmids that encode for such enzymes.
    Type: Application
    Filed: November 29, 2021
    Publication date: December 28, 2023
    Inventors: J. GREGORY REID, JAYACHANDRA P. REDDY, MATT GREGORY, URSULA SCHELL, BERNHARD J. PAUL
  • METHODS OF MAKING CHOLIC ACID DERIVATIVES AND STARTING MATERIALS THEREFOR
    Publication number: 20220298202
    Abstract: Methods of making cholic acid derivatives, particularly ursodeoxycholic acid, tauroursodeoxycholic acid, 7-ketolithocholic acid, obeticholic acid, their carboxylate salts and carboxylate esters, and starting materials and intermediates therefor.
    Type: Application
    Filed: June 5, 2022
    Publication date: September 22, 2022
    Inventors: J. Gregory Reid, Jayachandra P Reddy, Bernhard J. Paul, Sk Samad Hossain
  • Methods of making cholic acid derivatives and starting materials therefor
    Patent number: 11384116
    Abstract: Methods of making cholic acid derivatives, particularly ursodeoxycholic acid, tauroursodeoxycholic acid, 7-ketolithocholic acid, obeticholic acid, their carboxylate salts and carboxylate esters, and starting materials and intermediates therefor.
    Type: Grant
    Filed: August 11, 2021
    Date of Patent: July 12, 2022
    Assignee: Sandhill One, LLC
    Inventors: J. Gregory Reid, Jayachandra P Reddy, Bernhard J. Paul, Sk Samad Hossain
  • METHODS OF MAKING CHOLIC ACID DERIVATIVES AND STARTING MATERIALS THEREFOR
    Publication number: 20220056070
    Abstract: Methods of making cholic acid derivatives, particularly ursodeoxycholic acid, tauroursodeoxycholic acid, 7-ketolithocholic acid, obeticholic acid, their carboxylate salts and carboxylate esters, and starting materials and intermediates therefor.
    Type: Application
    Filed: August 11, 2021
    Publication date: February 24, 2022
    Inventors: J. Gregory Reid, Jayachandra P Reddy, Bernhard J. Paul, Sk Samad Hossain
  • Preparation and use of 7-[(2-carboalkoxy-1-methylethenyl)amino]-3-hydroxymethyl-3-cephem-4-carb oxylic acids
    Patent number: 5637694
    Abstract: This invention relates to a method of producing 3-alkanoyloxymethyl-3-cephem-4-carboxylic acids from 3-hydroxymethyl-3-cephem-4-carboxylic acids in an aqueous medium for a practical, large-scale production. Moreover, the invention provides an ideal intermediate for the process.
    Type: Grant
    Filed: April 5, 1996
    Date of Patent: June 10, 1997
    Assignee: Briston-Myers Squibb Company
    Inventors: J. Gregory Reid, Paul R. Brodfuehrer, Patrick R. Smith
  • Preparation and use of 7-[(2-carboalkoxy-1-methylethenyl)amino]-3-hydroxymethyl-3-cephem-4-carb oxylic acids
    Patent number: 5552542
    Abstract: This invention relates to a method of producing 3-alkanoyloxymethyl-3-cephem-4-carboxylic acids from 3-hydroxymethyl-3-cephem-4-carboxylic acids in an aqueous medium for a practical, large-scale production. Moreover, the invention provides an ideal intermediate for the process.
    Type: Grant
    Filed: May 10, 1995
    Date of Patent: September 3, 1996
    Assignee: Bristol-Myers Squibb Company
    Inventors: J. Gregory Reid, Paul R. Brodfuehrer, Patrick R. Smith