Abstract: The invention relates to a method for registering, identifying and processing of data related to chemical compounds including the steps of: (a) entering information on structure and properties of known chemical compounds into a first group of data bases; (b) entering information on genes, including alleles, RNAs and proteins into a second group of data bases; (c) entering information on known diseases and on epidemiology into a third group of data bases; (d) entering information on data relating to individual living organisms into a fourth group of data bases; (e) entering information on any known links between any of the data contained in any of the first, second, third and forth groups of data bases into a fifth group of data bases; (f) developing a tool for mining and visualizing of data; and (g) applying the tool for mining and visualizing of data to generate new knowledge on effects of chemical compounds, alleles and gene products on given individual living organisms.

Abstract: The invention relates to a method for registration, identifying and processing of drug specific data and for making drugs available to individual patients without severe adverse drug reactions. The invention relates also to a system for carrying out such a method. According to the present invention, the system comprises a master database correlating patterns of gene expression and genetic polymorphisms with drug-induced i.e. drug-related adverse effects and drug structure. The system also comprises a predictive data-tool. In this tool the structural and genetic fingerprints predictive for adverse effects in individual patients due to treatment with a selected drug are stored.

Abstract: An override clutch device is disclosed for use in a vacuum cleaner having a powered rotary brush. The override clutch device is arranged such that should the torque require to rotate the brush exceeds a predetermined level, the drive mechanism is disengaged from the brush thereby allowing the drive belt to continue to operate without damage. An audible signal is emitted to alert the operator of the malfunction.