Patents by Inventor J. Guy Breitenbucher

J. Guy Breitenbucher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080300255
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
    Type: Application
    Filed: July 24, 2008
    Publication date: December 4, 2008
    Inventors: Mary Pat Beavers, J. Guy Breitenbucher, Hui Cai, James P. Edwards, Cheryl A. Grice, Darin J. Gustin, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Kevin L. Tays, Jianmei Wei
  • Publication number: 20080293732
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
    Type: Application
    Filed: July 24, 2008
    Publication date: November 27, 2008
    Inventors: Mary Pat Beavers, J. Guy Breitenbucher, Hui Cai, James P. Edwards, Cheryl A. Grice, Darin J. Gustin, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Kevin L. Tays, Jianmei Wei
  • Patent number: 7456208
    Abstract: Certain imidazole compounds are CCK1 modulators useful in the treatment of CCK1 mediated diseases.
    Type: Grant
    Filed: July 3, 2007
    Date of Patent: November 25, 2008
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: J. Guy Breitenbucher, Michael D. Hack, Clark A. Sehon
  • Patent number: 7452890
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
    Type: Grant
    Filed: September 7, 2006
    Date of Patent: November 18, 2008
    Assignee: Ortho McNeil Pharmaceutical, Inc.
    Inventors: Mary Pat Beavers, J. Guy Breitenbucher, Hui Cai, James P. Edwards, Cheryl A. Grice, Darin J. Gustin, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Kevin L. Tays, Jianmei Wei
  • Patent number: 7429591
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
    Type: Grant
    Filed: September 7, 2006
    Date of Patent: September 30, 2008
    Assignee: Ortho McNeil Pharmaceutical, Inc.
    Inventors: Mary Pat Beavers, J. Guy Breitenbucher, Hui Cai, James P. Edwards, Cheryl A. Grice, Darin J. Gustin, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Kevin L. Tays, Jianmei Wei
  • Patent number: 7417046
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
    Type: Grant
    Filed: September 7, 2006
    Date of Patent: August 26, 2008
    Assignee: Ortho McNeil Pharmaceutical, Inc.
    Inventors: Mary Pat Beavers, J. Guy Breitenbucher, Hui Cai, James P. Edwards, Cheryl A. Grice, Darin J. Gustin, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Kevin L. Tays, Jianmei Wei
  • Patent number: 7393850
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
    Type: Grant
    Filed: September 7, 2006
    Date of Patent: July 1, 2008
    Assignee: Ortho McNeil Pharmaceutical, Inc.
    Inventors: Mary Pat Beavers, J. Guy Breitenbucher, Hui Cai, James P. Edwards, Cheryl A. Grice, Darin J. Gustin, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Kevin L. Tays, Jianmei Wei
  • Patent number: 7388011
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
    Type: Grant
    Filed: September 7, 2006
    Date of Patent: June 17, 2008
    Assignee: Ortho McNeil Pharmaceutical, Inc.
    Inventors: Mary Pat Beavers, J. Guy Breitenbucher, Hui Cai, James P. Edwards, Cheryl A. Grice, Darin J. Gustin, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Kevin L. Tays, Jianmei Wei
  • Patent number: 7332494
    Abstract: A method for treating an allergic condition, including an atopic allergic condition, using substituted pyrazoles.
    Type: Grant
    Filed: February 13, 2002
    Date of Patent: February 19, 2008
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: J. Guy Breitenbucher, Hui Cai, James P. Edwards, Cheryl A. Grice, Yin Gu, Darin J. Gustin, Lars Karlsson, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Siquan Sun, Kevin L. Tays, Robin L. Thurmond, Jianmei Wei
  • Patent number: 7309703
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S are described.
    Type: Grant
    Filed: August 10, 2001
    Date of Patent: December 18, 2007
    Assignee: Ortho McNeil Pharmaceutical, Inc.
    Inventors: Mary Pat Beavers, J. Guy Breitenbucher, Hui Cai, James P. Edwards, Cheryl A. Grice, Darin J. Gustin, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Kevin L. Tays, Jianmei Wei
  • Patent number: 7271261
    Abstract: 2-Aryl substituted benzimidazoles and imidazo[4,5]pyridines are disclosed as inhibitors of Cds1 and useful as adjuvants to chemotherapy or radiation therapy in the treatment of cancer.
    Type: Grant
    Filed: October 18, 2002
    Date of Patent: September 18, 2007
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Kristen L. Arienti, Frank U. Axe, J. Guy Breitenbucher, Liming Huang, Alice Lee, Kelly J. McClure
  • Patent number: 7250427
    Abstract: Aryl substituted benzimidazole and imidazo[4,5]pyridine ethers are described as inhibitors of Cds1 and useful as adjuvants to chemotherapy or radiation therapy in the treatment of cancer.
    Type: Grant
    Filed: June 27, 2005
    Date of Patent: July 31, 2007
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: J. Guy Breitenbucher, Alice Lee-Dutra, Danielle K. Neff
  • Patent number: 7250434
    Abstract: Certain imidazole compounds are CCK1 modulators useful in the treatment of CCK1 mediated diseases.
    Type: Grant
    Filed: December 21, 2004
    Date of Patent: July 31, 2007
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: J. Guy Breitenbucher, Michael D. Hack, Clark A. Sehon
  • Patent number: 7199117
    Abstract: The invention features pharmaceutically-active imidazopyridines and derivatives that are substituted with phenyl, methods of making them, and methods of using them.
    Type: Grant
    Filed: October 7, 2004
    Date of Patent: April 3, 2007
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: J. Guy Breitenbucher, Nicholas I. Carruthers, Xiaobing Li, Laura C. McAtee, Chandravadan R. Shah, Ronald L. Wolin
  • Patent number: 7132440
    Abstract: 2-Aryl substituted benzimidazoles and imidazo[4,5]pyridines are disclosed as inhibitors of Cds1 and useful as adjuvants to chemotherapy or radiation therapy in the treatment of cancer.
    Type: Grant
    Filed: April 16, 2004
    Date of Patent: November 7, 2006
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: Michael K. Ameriks, Kristen L. Arienti, Frank U. Axe, J. Guy Breitenbucher
  • Patent number: 7087757
    Abstract: The invention features pharmaceutically-active imidazopyridines and derivatives that are substituted with phenyl, methods of making them, and methods of using them.
    Type: Grant
    Filed: October 7, 2004
    Date of Patent: August 8, 2006
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: J. Guy Breitenbucher, Nicholas I. Carruthers, Xiaobing Li, Laura C. McAtee, Chandravadan R. Shah, Ronald L. Wolin
  • Patent number: 7041828
    Abstract: The invention features pharmaceutically-active imidazopyridines and derivatives that are substituted with phenyl, methods of making them, and methods of using them.
    Type: Grant
    Filed: October 7, 2004
    Date of Patent: May 9, 2006
    Inventors: J. Guy Breitenbucher, Nicholas I. Carruthers, Xiaobing Li, Laura C. McAtee, Chandravadan R. Shah, Ronald L. Wolin
  • Patent number: 7041827
    Abstract: The invention features pharmaceutically-active imidazopyridines and derivatives that are substituted with phenyl, methods of making them, and methods of using them.
    Type: Grant
    Filed: October 7, 2004
    Date of Patent: May 9, 2006
    Inventors: J. Guy Breitenbucher, Nicholas I. Carruthers, Xiaobing Li, Laura C. McAtee, Chandravadan R. Shah, Ronald L. Wolin
  • Patent number: 7037931
    Abstract: There are provided by the present invention certain pyrazole based CCK-1 receptor modulators.
    Type: Grant
    Filed: July 2, 2003
    Date of Patent: May 2, 2006
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Terrance D. Barrett, J. Guy Breitenbucher, Laurent Gomez, Michael D. Hack, Liming Huang, Kelly J. McClure, Magda F. Morton, Clark A. Sehon, Nigel P. Shankley
  • Patent number: 6908929
    Abstract: The invention features pharmaceutically-active imidazopyridines and derivatives that are substituted with phenyl, methods of making them, and methods of using them.
    Type: Grant
    Filed: March 29, 2001
    Date of Patent: June 21, 2005
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: J. Guy Breitenbucher, Nicholas I. Carruthers, Xiaobing Li, Laura C. McAtee, Chandravadan R. Shah, Ronald L. Wolin