Abstract: Methods for determining the probability of cardiac disease indicators by utilizing an optimal lead set to measure electrocardiographic data to find the measurement extrema over an optimum portion of the Thorax. The optimal lead topology is designed to produce estimates of total thoracic electrocardiographic information, low noise and errors within the constraints imposed by the measured leads' associated constraint set, which include disease targets. Importantly an optimal electrode topology and measured lead set is deemed optimal when the estimated lead topology provides the lowest global estimation errors. An optimum electrode topology is one that places the electrodes in arbitrary, but optimal, positions on the Thorax and not in a grid like manner (such as used by a BSPM vest electrode array) nor necessarily in those positions used in current practice such as for standard 12 lead or EASI leads.

Abstract: A body worn harness supporting biosensors and devices in a form fitting structure for medical long-term ambulatory operation. The supported devices provide processing, storage, and communicating of the biosensor data captured. Integrated body motion generators generate power. In addition rapid acting zero insertion force mechanical and electrical connectors are provided for the interconnection of the biosensors, devices, and power sources.

Abstract: A non-invasive body worn computing platform is capable of long term unattended operation to capture, analyze, store, biosensor data and communicate health and system events, ECG waves and other biomedical data from the patient recorded, produced, or analyzed. The non-invasive body worn computing platform operates as a node within a wireless distributed collaborative network. The body worn computing platform has a latch-able mechanical and electrical interface for rapid swapping of the device and power source to and from biosensors, body harness, and power sources.