Abstract: Methods and devices for cardiac therapy. One example provides a subcutaneous anti-tachycardia pacing therapy. Another example provides a subcutaneous low energy cardioversion therapy. Yet another example provides a subcutaneous multiple pulse cardioversion therapy. In various examples, specific steps are taken to ensure synchronization of delivered therapy when provided in response to sensing and analysis of a subcutaneous signal. Some examples use a substernal device instead.

Abstract: Methods, systems and devices for providing cardiac resynchronization therapy (CRT) to a patient using a leadless cardiac pacemaker (LCP) and an extracardiac device (ED). The LCP is configured to deliver pacing therapy at a pacing interval. Illustratively, the ED may be configured to analyze the cardiac cycle including a portion preceding the pacing therapy delivery for one or several cardiac cycles, and determine whether an interval from the P-wave to the pace therapy in the cardiac cycle(s) is in a desired range. In an example, if the P-wave to pace interval is outside the desired range, the ED communicates to the LCP to adjust the pacing interval.

Abstract: A trimmer razor including a handle, a head operatively connected to the handle, the head including a base member, a seat extending from the base member, and a cover connected to the seat, and an extension arrangement connecting the cover to the handle so that, upon rotation of the handle. The cover is movable between an open position and a closed position.

Abstract: A method for autonomous control of electric power consumption by an apparatus includes monitoring electric power measurement data of electric power generated by a solar array of the apparatus. The solar array is configured to at least charge a battery and provide electrical power to components of the apparatus. The method also includes monitoring a state of charge of the battery and autonomously controlling electric power consumption of an integrated payload array in response to at least the state of charge of the battery. The state of charge of the battery is maintained proximate a preset threshold.

Abstract: Determining a type of actor performing an activity includes monitoring the performance of the activity via at least one sensor to produce activity readings over a dimension. The activity readings are then compared to reference readings that are generated based on a machine performing same activity. The comparison of the reference readings to the activity readings is used to determine a variance between the activity readings and reference readings. Once the variance is determined, the variance is compared with a threshold value to determine the type of actor performing the activity.

Abstract: An example operation may include one or more of determining an energy state of a system, generating a wireless energy transfer request based on the energy state, transmitting the wireless energy transfer request to another system, receiving wireless energy transfer information from the other system, performing a wireless energy exchange with the other system based on the wireless energy transfer information, and receiving a data block associated with the wireless energy exchange from the other system.

Abstract: A medical system includes a physiological monitoring system configured to sense a physiological signal and record physiological signal data indicative of the patient's physiological state. The physiological monitoring system including a controller, a storage device, at least one sensor operatively coupled to the controller, and a first communication component. The system includes a mobile device configured to facilitate sensor placement, the mobile device comprising a controller, a display device, and a second communication component configured to facilitate communication between the physiological monitoring system and the mobile device. The controller of the mobile device is configured to provide a graphical user interface (GUI) on the display device, the GUI including information about a proper placement of the at least one sensor, wherein the proper placement is determined based on the physiological signal data.

Abstract: Provided are techniques for mitigating security risks utilizing continuous device image reload with data integrity. Continuous reload of a first image on a device in an Internet of Things (IoT) group of devices coupled to an IoT service is performed based on triggers. A trigger from the triggers is received that indicates one of that a period of time has expired, that notification of a known infection has been received, and that there has been failure of an internal onboard security check. A second image is obtained that is not infected from the IoT service. The device is reloaded with the second image to replace the first image with the second image.

Abstract: In a method for device unavailability management within a network, a network device selects an advocate device as an agent of the network device. The network device defines a set of actions to be executed when the network device ever becomes unavailable. The set of actions is stored in a datastore and associated with the network device. Upon determining that the network device has become unavailable, the advocate device is notified and obtains the set of actions associated with the network device. The advocate device then executes the set of actions by the advocate device.

Abstract: Systems, methods and implantable devices configured to provide cardiac resynchronization therapy and/or bradycardia pacing therapy. A first device located in the heart of the patient is configured to receive a communication from a second device and deliver a pacing therapy in response to or in accordance with the received communication. A second device located elsewhere is configured to determine an atrial event has occurred and communicate to the first device to trigger the pacing therapy. The second device may be configured for sensing the atrial event by the use of vector selection and atrial event windowing, among other enhancements. Exception cases are discussed and handled as well.

Abstract: An example of a system and method for protecting a patient diagnosed of cancer from cardiac injury resulting from a chemotherapy treating the cancer. A sequence of cardioprotective pacing sessions may be initiated based on timing of the chemotherapy. Cardiac pacing pulses may be delivered to the patient during each session of the cardioprotective pacing sessions according to a cardioprotective pacing mode for controlling delivery of the cardiac pacing pulses to effect cardioprotection against potential myocardial injury resulting from the chemotherapy. The cardioprotective pacing mode may specifying alternating non-pacing and pacing periods.

Abstract: Provided are techniques for grouping devices as a virtual device for providing better quality of device data. A group of devices in an Internet of Things (IoT) network is identified based on one or more attributes of each of the devices. The group of devices is provided as a single virtual device by: collecting data from each of the devices in the group, transforming the data, and using the transformed data to modify a device.

Abstract: A method, a device and a computer program product are provided. A networked device determines whether a condition occurred. In response to detecting the condition, the networked device requests information to update a current credential of the networked device. The networked device updates the current credential with the requested information to maintain security of the networked device. The networked device accesses at least one networked service based on the updated credential. The current credential includes either a cryptographic key or a password. When the current credential includes the password, the condition includes a usage rate including one or more from a group of a quantity of reboot commands for the networked device and a quantity of software update commands for the networked device.

Abstract: A method for recovering a composition enriched in 3-hydroxypropionic acid by providing the fermentation broth, acidifying the fermentation broth; reducing the total sulfate ion and phosphate ion concentration of the resulting gaqueous solution to produce a reduced ion aqueous solution; distilling the resulting reduced ion aqueous solution and recovering the resulting aqueous distillation product comprising 3-hydroxypropioriic acid

Abstract: A method for recovering a composition enriched in 3-hydroxypropionic acid from a fermentation broth comprising 3-hydroxypropionic acid and/or salts thereof comprises the steps of: (a) providing the fermentation broth having a pH of from about 2 to about 8 comprising 3-hydroxypropionic acid and/or salts thereof (b) acidifying the fermentation broth; (c) reducing the total sulfate ion and phosphate ion (d) distilling the resulting reduced ion aqueous solution and (e) recovering the product.

Abstract: Methods are provided for treating cancers using a conjugate herein described as Conjugate 5, or a pharmaceutically acceptable salt thereof. Methods for treating cancers using Conjugate 5, or a pharmaceutically acceptable salt thereof, to target tumor associated macrophages are also described.

Abstract: In the sharing of data between connected devices over a network, a network device broadcasts an availability of a set of data collected by a data producing device coupled to the network. The network device receives a request to access the set of data from a data consuming device coupled to the network, and a cognitive computing module of the network device determines a set of terms between the data producing and the data consuming devices for access to the set of data. In response, the network device obtains the set of data and a first key from the data producing device. Upon receiving a second key from the data consuming device, the network device determines that the second key is associated with the first key. In response, the network device provides access to the set of data to the data consuming device according to the set of terms.

Abstract: According to one embodiment of the present invention, a system provides security for a device and includes at least one processor. The system monitors a plurality of networked devices for a security risk. Each networked device is associated with a corresponding security risk tolerance. In response to a monitored security risk for one or more of the plurality of networked devices exceeding the corresponding risk tolerance, a network service is initiated to perform one or more actions on each of the one or more networked devices to alleviate the associated security risk. Embodiments of the present invention further include a method and computer program product for providing security to a device in substantially the same manner described above.

Abstract: Provided are techniques for grouping devices as a virtual device for providing better quality of device data. A group of devices in an Internet of Things (IoT) network is identified based on one or more attributes of each of the devices. The group of devices is provided as a single virtual device by: collecting data from each of the devices in the group, transforming the data, and using the transformed data to modify a device.

Abstract: Systems, methods and implantable devices configured to provide cardiac resynchronization therapy and/or bradycardia pacing therapy. A first device located in the heart of the patient is configured to receive a communication from a second device and deliver a pacing therapy in response to or in accordance with the received communication. A second device located elsewhere is configured to determine an atrial event has occurred and communicate to the first device to trigger the pacing therapy. The second device may be configured for sensing the atrial event by the use of vector selection and atrial event windowing, among other enhancements. Exception cases are discussed and handled as well.