Patents by Inventor J. Harold Helderman

J. Harold Helderman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Monocyte-derived insulin receptor regulatory factor
    Patent number: 5371189
    Abstract: The present invention relates to a purified monocyte-derived insulin receptor regulatory factor, which has the biological activity of reducing insulin receptor binding on T-lymphocytes. Additionally, the invention relates to a nucleic acid that codes for the monocyte-derived insulin receptor regulatory factor, a recombinant protein produced therefrom, and an antibody to the factor. The present invention also relates to a method of reducing insulin receptor binding on activated T-lymphocytes, including administration of the protein to a subject.
    Type: Grant
    Filed: April 30, 1993
    Date of Patent: December 6, 1994
    Assignee: Vanderbilt University
    Inventor: J. Harold Helderman