Abstract: An electrically operated displacement pump includes an electric motor having a stator and a rotor. The rotor is connected to the fluid displacer to power pumping by the fluid displacer. A cooling circuit extends at least partially about an exterior of a motor housing that houses the electric motor. A fan assembly blows cooling air through the cooling circuit.

Abstract: Gene therapy compositions and methods are provided that make use of novel transposases and/or chimeric transposases for targeted transposition.

Abstract: The present disclosure provides a dispersive optical device (DOD) that includes a first material having a first refractive index (n1) at a first wavelength (W1) and a first chromatic dispersion (D1); and at least one dispersive optical element (DOE) optically coupled in the first material, the at least one DOE comprising a second material containing a chromophore. The at least one DOE has a second refractive index (n2) at W1; a ratio of n2 to n1 is less than or equal to about 1.05; and the at least one DOE has a second chromatic dispersion (D2), wherein D2 is at least 10 times greater than D1.

Abstract: The present invention comprises at least sensing, monitoring, and display of motor current which is then used in various embodiments of a rotational atherectomy device to determine and/or predict, among other things, treatment progression, treatment completion, optimal rotational speed, optimal advancement or traversal speed during treatment, whether stall appears imminent, and/or reacting to stop motor rotation before a stall occurs. In some embodiments, the determination or prediction results in an automatic, or preprogrammed adjustment by the control unit of the rotational speed of the rotating drive shaft and associated tool.

Abstract: An aerial lift that is interlocked with a fall-protection safety apparatus and may be further interlocked with at least one additional safety apparatus. The aerial lift is equipped with a monitoring system that is configured to detect whether a connector of a safety line of the fall-protection apparatus appears to be connected to a safety harness of a user of the aerial lift.

Abstract: A multispectral inspection (MSI) device for analyzing an electronic item having a printed circuit board (PCB). An electronic power supply powers the electronic item in accordance with one or more test vectors. An optical imaging scanner, terahertz (THz) imaging scanner, and a functional imaging scanner are each operative to scan the electronic item. An electronic processor is programmed to scan the various scanners and control the power supply to acquire optical, THz, and functional images of the electronic item. The images are combined to form a standard three-dimensional (3D) signature and artificial intelligence (AI) classifiers are applied to the 3D signature to perform non-destructive analyses of the electronic item.

Abstract: A system for transmitting images. The system comprises a first camera having a first camera module having a first sensor configured to capture a first image, the first image including a timestamp, an SD card configured to store the first image, a plurality of light-emitting diodes, a first display configured to display the first image, a first plurality of buttons associated with the first display, and a first communication module programmed to transmit the first image through a low-power communication network. The system further includes a home node configured to be powered by a second plurality of batteries. The home node includes a second communication module programmed to receive the first image from the first communication module over the low-power communication network, a second display configured to display the first image, and a second plurality of buttons associated with the second display.

Abstract: Various embodiments of devices and systems comprising a polymer driveshaft for use in high-speed rotational medical procedures, e.g., atherectomy, are disclosed. Generally, the primary driveshaft for transferring torque and activating rotation of a tool attached thereto, e.g., an abrasive element, is constructed with at least a polymer outer and inner surface. In certain embodiments, the polymer driveshaft may comprise a metallic band for fixed attachment of a structure, e.g., an abrasive element, thereto. Various embodiments may comprise a coupler that connects a drive shaft connected with a prime mover, e.g., a turbine or electric motor, with the polymer drive shaft, the coupler comprising openings through the coupler wall to the inner diameter of the coupler to allow fluid flow to the inner diameter of the coupled polymer drive shaft.

Abstract: Embodiments of delivery systems, devices and methods for delivering a prosthetic heart valve device to a heart chamber for expanded implementation are disclosed. More specifically, methods, systems and devices are disclosed for delivering a self-expanding prosthetic mitral valve device to the left atrium, with no engagement of the left ventricle, the native mitral valve leaflets or the annular tissue downstream of the upper annular surface during delivery, and in some embodiments with no engagement of the ventricle, mitral valve leaflets and/or annular tissue located downstream of the upper annular surface by the delivered, positioned and expanded prosthetic mitral valve device.

Abstract: Provided herein are systems, devices, and methods for performing a medical procedure on a patient. The system comprises an ablation catheter comprising a shaft, at least one therapeutic element positioned on the shaft, and one or more tissue-contact sensing components configured to provide a contact signal related to the level of contact between the at least one therapeutic element and tissue. The system further comprises: an energy delivery unit configured to deliver ablative energy to the at least one therapeutic element to create a lesion in target tissue, and to provide an energy delivery data; a force module configured to receive the contact signal and provide contact data; and a processing unit configured to determine an ablation index based on both the energy delivery data and the contact data. The ablation index can represent the status of the lesion being created.

Abstract: A system for inspecting a wire segment includes an inspection apparatus and a visual imaging device. The apparatus includes an array of mirrors positioned about a centerline of the apparatus, wherein each mirror in the array is oriented such that a reflection of a first inspection zone of the wire segment in the array of mirrors forms a circumferential view of the first inspection zone of the wire segment, and the reflection from each mirror is within a field of view from a single vantage point. The visual imaging device is positioned at the single vantage point and oriented towards the wire segment such that the reflection from each mirror of the array of mirrors is within a field of view of the visual imaging device, the visual imaging device configured to capture at least one image of the reflection of the wire segment from the array of mirrors.

Abstract: A medical device is configured to detect an atrial tachyarrhythmia episode. The device senses a cardiac signal, identifies R-waves in the cardiac signal attendant ventricular depolarizations and determines classification factors from the R-waves identified over a predetermined time period. The device classifies the predetermined time period as one of unclassified, atrial tachyarrhythmia and non-atrial tachyarrhythmia by comparing the determined classification factors to classification criteria. A classification criterion is adjusted from a first classification criterion to a second classification criterion after at least one time period being classified as atrial tachyarrhythmia. An atrial tachyarrhythmia episode is detected by the device in response to at least one subsequent time period being classified as atrial tachyarrhythmia based on the adjusted classification criterion.

Abstract: Certain aspects are directed to an ophthalmic specialty instrument configured to allow patients to treat MGD and other dry eye conditions themselves which is easy to operate and more effective. The ophthalmic specialty instrument comprises a main body of two arms with a distal end and a proximal end; wherein the two arms are pivotably coupled to a common connection point at the proximal end and a pair of angled and slightly wedged pressure plates are attached to the distal end of the two arms; wherein an exfoliating member is also attached to the proximal end; and wherein the pressure plates are angled downwardly and outwardly from the longitudinal planes of the arms and have gentle radius of curvature that match the curvature of eyelids to facilitate a substantially 90° approaching angle to the eyelid margin as opposed to making contact with the eyelids tangentially.

Abstract: A method for protecting content, comprising receiving, from a client device, a request for an encryption key for encrypting the content comprising a reference associated with the client device, identifying a set of supported security capabilities corresponding to the reference associated with the client device, identifying a set of required security capabilities corresponding to the content associated with the key request, determining if the set of supported security capabilities satisfy the set of required security capabilities, and in response to determining that the supported security capabilities satisfy the set of required security capabilities, transmitting the encryption key to the client device.

Abstract: A multispectral inspection (MSI) device for analyzing an electronic item having a printed circuit board (PCB). An electronic power supply powers the electronic item in accordance with one or more test vectors. An optical imaging scanner, terahertz (THz) imaging scanner, and a functional imaging scanner are each operative to scan the electronic item. An electronic processor is programmed to scan the various scanners and control the power supply to acquire optical, THz, and functional images of the electronic item. The images are combined to form a standard three-dimensional (3D) signature and artificial intelligence (AI) classifiers are applied to the 3D signature to perform non-destructive analyses of the electronic item.

Abstract: A vehicular imaging system includes a camera disposed behind a windshield of a vehicle and viewing through a portion of the windshield. Image data captured by the camera is provided to a control. The control receives, via a communication bus of the vehicle, at least one selected from the group consisting of (i) vehicle pitch information relating to pitch of the vehicle, (ii) vehicle yaw information relating to yaw of the vehicle and (iii) vehicle steering information relating to steering of the vehicle. The system automatically corrects for misalignment of the camera. Image data captured by the camera is processed at the control for a lane departure warning system of the vehicle and for at least one selected from the group consisting of (i) an automatic headlamp control system of the vehicle, (ii) a collision avoidance system of the vehicle and (iii) an adaptive front lighting system of the vehicle.

Abstract: An occlusion clearing device for a patient has a housing with a motor(s) that generates repetitive motion, which is reciprocating, rotational or both. A clearing stem including a sheath that has a lumen, wherein aspiration is conducted through the sheath lumen. A wire is located in the sheath lumen and receives repetitive motion from the controller. The sheath terminates in a sheath end having at least one sheath opening. The wire terminates in a wire tip, which may be flat, helical, or tubular. The wire tip is positioned within the sheath end, in proximity to the sheath opening(s), and movement of the wire tip and/or sheath end relative to each other creates shearing forces that break up an adjacent occlusion.

Abstract: Recombinant mammalian helper enzymes for targeted transposition are described. The mammalian helper enzymes and corresponding donor DNAs can be used, e.g., for gene therapy.

Abstract: A medical device is configured to detect an atrial tachyarrhythmia episode. The device senses a cardiac signal, identifies R-waves in the cardiac signal attendant ventricular depolarizations and determines classification factors from the R-waves identified over a predetermined time period. The device classifies the predetermined time period as one of unclassified, atrial tachyarrhythmia and non-atrial tachyarrhythmia by comparing the determined classification factors to classification criteria. A classification criterion is adjusted from a first classification criterion to a second classification criterion after at least one time period being classified as atrial tachyarrhythmia. An atrial tachyarrhythmia episode is detected by the device in response to at least one subsequent time period being classified as atrial tachyarrhythmia based on the adjusted classification criterion.

Abstract: A system for sensing physiological traits of a maternal patient and a fetal patient carried by the maternal patient during a pregnancy using one or more sensors. The system may use the physiological traits sensed to define a maternal attribute for the maternal patient and a fetal attribute for the fetal patient, such as a heart rate, blood pressure, respiration rate, temperature, oxygen saturation level, or other attributes. The system is configured to compare the maternal attribute to a maternal limit describing a threshold for the maternal patient and/or compare the fetal attribute to a fetal limit describing a threshold for the fetal patient. The system is configured to issue a communication to the maternal patient and/or a clinician based on the comparisons. In examples, the system regularly communicates the maternal attribute and/or the fetal attribute to an output device of the maternal patient and/or a clinician.