Patents by Inventor J. J. Wright

J. J. Wright has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bis-aryl sulfonamides
    Publication number: 20050137179
    Abstract: Compounds are provided that act as potent antagonists of chemokine receptors. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of chemokine receptor-mediated diseases, and as controls in assays for the identification of chemokine antagonists.
    Type: Application
    Filed: May 19, 2004
    Publication date: June 23, 2005
    Inventors: Solomon Ungashe, Zheng Wei, J. J. Wright, Andrew Pennell, Brett Premack, Thomas Schall
  • Indole, azaindole and related heterocyclic N-substituted piperazine derivatives
    Publication number: 20050075364
    Abstract: This invention provides compounds of Formula I, including pharmaceutically accceptable salts thereof, having drug and bio-affecting properties, their pharmaceutical compositions and method of use. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS.
    Type: Application
    Filed: June 18, 2004
    Publication date: April 7, 2005
    Inventors: Kap-Sun Yeung, Michelle Farkas, John Kadow, Nicholas Meanwell, Malcolm Taylor, David Johnston, Thomas Coulter, J. J. Wright
  • Arylamines as inhibitors of chemokine binding to US28
    Patent number: 6821998
    Abstract: Methods for treating CMV and CMV-related diseases are provided that use compounds having the formula: wherein the subscripts m and n are each independently integers from 1 to 2; and the R groups are as defined in the specification.
    Type: Grant
    Filed: August 29, 2002
    Date of Patent: November 23, 2004
    Assignee: ChemoCentryx, Inc.
    Inventors: Brian E. McMaster, Thomas J. Schall, Mark Penfold, J. J. Wright, Daniel J. Dairaghi
  • Inhibitors of human tumor-expressed CCXCKR2
    Publication number: 20040171655
    Abstract: Pharmaceutical compositions containing organic compounds or salts thereof that serve as modulators for the SDF-1 or I-TAC chemokines are disclosed. The compounds and compositions are useful in the treatment of cancer, especially in the inhibition of cancer proliferation, growth, and metastasis. Methods of interfering with SDF-1 and/or I-TAC binding to the CCXCKR2 receptor and treating cancer using the compounds and pharmaceutical compositions of the present invention are also disclosed.
    Type: Application
    Filed: December 22, 2003
    Publication date: September 2, 2004
    Inventors: Anita Melikian, Jennifer Burns, Brian E. McMaster, Thomas Schall, J.J. Wright
  • Aryl sulfonamides
    Publication number: 20040171654
    Abstract: Compounds are provided that act as potent antagonists of the CCR9 receptor, and which have been further confirmed in animal testing for inflammation, one of the hallmark disease states for CCR9. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR9-mediated diseases, and as controls in assays for the identification of CCR9 antagonists.
    Type: Application
    Filed: November 17, 2003
    Publication date: September 2, 2004
    Inventors: Solomon Ugashe, Zheng Wei, J. J. Wright, Andrew Pennell
  • Bis-aryl sulfonamides
    Publication number: 20040167113
    Abstract: Compounds are provided that act as potent antagonists of chemokine receptors. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of chemokine receptor-mediated diseases, and as controls in assays for the identification of chemokine antagonists.
    Type: Application
    Filed: November 18, 2003
    Publication date: August 26, 2004
    Inventors: Solomon Ugashe, Zheng Wei, J.J. Wright, Andrew Pennell, Brett Premack, Thomas Schall
  • Bicyclic compounds as inhibitors of chemokine binding to US28
    Publication number: 20030149055
    Abstract: Methods for treating CMV or a CMV-related disease are provided that use compounds having the formula: 1
    Type: Application
    Filed: August 29, 2002
    Publication date: August 7, 2003
    Applicant: ChemoCentryx
    Inventors: Brian E. McMaster, Thomas J. Schall, Mark Penfold, J. J. Wright, Daniel J. Dairaghi
  • Arylamines as inhibitors of chemokine binding to US28
    Publication number: 20030114423
    Abstract: Methods for treating CMV and CMV-related diseases are provided that use compounds having the formula: 1
    Type: Application
    Filed: August 29, 2002
    Publication date: June 19, 2003
    Applicant: ChemoCentryx, Inc.
    Inventors: Brian E. McMaster, Thomas J. Schall, Mark Penfold, J.J. Wright, Daniel J. Dairaghi