Abstract: A valve device for medical fluid transfer and methodology utilizing the valve device provides a multi-purpose needle free valve assembly and bottle or IV port adapters for multiple medical use requirements. The adapters being suitable for insertion into IV ports, medicine bottles or vials and IV luer lock connectors. The valve device assembly for fluid transfer is used within administration structures for medical purposes utilizing a needle free syringe as the transfer apparatus, the needle free syringe being mateable with the valve device assembly in a first connector and when inserted, the syringe tip opens the valve by compression of the valve head or piston and valve springs allowing for two-way communication between the barrel of the needle free syringe and the IV ports, medicinal bottles or vials and IV luer lock connectors.