Abstract: Ophthalmic lens molds include first and second mold members sized and adapted to be assembled, for example interference fitted, together to define a lens-shaped cavity therebetween. At least one of the mold members includes a polar polymeric material and has a flexural modulus less than 3800 MPa.

Abstract: Devices and methods for improving vision are described. The vision of a person can be corrected using a corneal onlay or a lens positioned between an epithelial cell layer and Bowman's membrane of the person's eye. Wavefront aberrations are measured for the person's eye or eyes, and the aberrations are used to shape the corneal onlay to provide a desired vision correction power, or to shape the person's cornea.

Abstract: Contact lenses ready for use in an eye are provided including a contact lens body containing a hydrophilic polymeric component and a water soluble polymer component. Such contact lenses, which preferably are wet cast molded, are particularly useful as disposable or single use lenses. New contact lens packaging systems and production methods are also provided.

Abstract: Contact lenses ready for use in an eye are provided including a contact lens body containing a hydrophilic polymeric component and a water soluble polymer component. Such contact lenses, which preferably are wet cast molded, are particularly useful as disposable or single use lenses. New contact lens packaging systems and production methods are also provided.

Abstract: Methods of sterilizing silicone hydrogel contact lenses include exposing one or more silicone hydrogel contact lenses to high energy radiation, such as gamma radiation or electron beam radiation. Sterilized contact lens packages containing such silicone hydrogel contact lenses are also described.

Abstract: Corneal onlays and corneal onlay production methods are described. The present corneal onlays include a lens body. An example of a corneal onlay includes a lens body that includes a corneal epithelium-contactable anterior surface and a Bowman's membrane-contactable posterior surface. The lens body has an optical power from about ?10 diopters to about +10 diopters, an optic zone diameter from about 5 mm to about 11 mm, a base curve from about 5 mm to about 12 mm, a center thickness from about 10 micrometers to about 300 micrometers, and an edge thickness from about 0 micrometers to about 120 micrometers. Methods include forming the present corneal onlays from polymeric materials.

Abstract: Contact lenses for use in eyes are provided and include a lens body and a plurality of microchannels defined in a posterior face of the lens body. The microchannels are structured to promote effective tear fluid exchange between an exposed surface of the eye and a surface of the eye covered by the lens body. Each of the microchannels preferably includes a substantially junctionless, convex surface along a major portion of a length of the microchannel.

Abstract: Methods for improving or correcting a patient's vision are provided which generally include inserting a lens within the stroma of an eye of the patient by forming an incision in the cornea and creating a pocket within the stroma for accommodating the lens, the method being accomplished without forming a flap incision.

Abstract: A contact lens is described that comprises a lens body and an epithelial growth factor (EGF) component. The EGF component is effective in maintaining a healthy epithelium of an eye on which the lens is placed. The EGF component includes an EGF, and preferably a human EGF. The lens may be effective in reducing irritation associated with conventional contact lenses, and also may be effective in treating dry eye and/or reducing infection of an eye. Packaging systems and method of manufacturing such lenses are also described.

Abstract: Devices and methods for improving vision are described. The vision of a person can be corrected using a corneal onlay or a lens positioned between an epithelial cell layer and Bowman's membrane of the person's eye. Wavefront aberrations are measured for the person's eye or eyes, and the aberrations are used to shape the corneal onlay to provide a desired vision correction power, or to shape the person's cornea.

Abstract: Contact lenses for use in eyes are provided and include a lens body and a plurality of microchannels defined in a posterior face of the lens body. The microchannels are structured to promote effective tear fluid exchange between an exposed surface of the eye and a surface of the eye covered by the lens body. Each of the microchannels preferably includes a substantially junctionless, convex surface along a major portion of a length of the microchannel.

Abstract: A corneal appliance that is placed over an eye has a lens body and epithelial cells secured over the lens body. The epithelial cells of the appliance may be derived from cultured cells, including stem cells, such as limbal stem cells, or epithelial cell lines, or may include at least a portion of the epithelium of the eye on which the appliance is placed. The corneal appliance may have a cellular attachment element between the lens body and the epithelial cells to facilitate attachment of the epithelial cells over the lens body. The corneal appliance is intended to be used on a deepithelialized eye, which may be an eye that has had the epithelium fully or partially removed. The corneal appliance may be used to improve vision. Methods of producing the corneal appliance and of improving vision are also disclosed.