Patents by Inventor J. Mauro

J. Mauro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220324979
    Abstract: The present disclosure describes combination therapies comprising an antagonist of Programmed Death 1 receptor (PD-1) and a VEGFR inhibitor, and the use of the combination therapies for the treatment of cancer, and in particular for treating cancers that express PD-L1.
    Type: Application
    Filed: April 20, 2022
    Publication date: October 13, 2022
    Applicants: PFIZER INC., MERCK SHARP & DOHME CORP.
    Inventors: Jean-Francois Andre MARTINI, Jamal Christo Tarazi, Rodolfo Fleury Perini, David J. Mauro
  • Publication number: 20200325228
    Abstract: The present disclosure describes combination therapies comprising an antagonist of Programmed Death 1 receptor (PD-1) and a VEGFR inhibitor, and the use of the combination therapies for the treatment of cancer, and in particular for treating cancers that express PD-L 1.
    Type: Application
    Filed: January 14, 2020
    Publication date: October 15, 2020
    Applicants: PFIZER INC., MERCK SHARPE & DOHME CORP.
    Inventors: Jean-Francois Andre Martini, Jamal Christo Tarazi, Rodolfo Fleury Perini, David J. Mauro
  • Patent number: 10570202
    Abstract: The present disclosure describes combination therapies comprising an antagonist of Programmed Death 1 receptor (PD-1) and a VEGFR inhibitor, and the use of the combination therapies for the treatment of cancer, and in particular for treating cancers that express PD-L1.
    Type: Grant
    Filed: February 3, 2015
    Date of Patent: February 25, 2020
    Assignees: Pfizer Inc., Merck Sharpe & Dohme Corp.
    Inventors: Jean-Francois Andre Martini, Jamal Christo Tarazi, Rodolfo Fleury Perini, David J. Mauro
  • Publication number: 20190212993
    Abstract: Computer implemented techniques are disclosed for identification of repeated binary strings and for storing those binary strings in order to compress code. The binary strings can be longer instructions, data, or addresses. A table of binary strings is generated based on repeated occurrences, and a reference index is provided for accessing specific entries within the table. An opcode uses a shorter string as an index through which to access the table. The longer string is executed when the longer string is an instruction. When the longer string is an address or data, the appropriate address or data arc accessed.
    Type: Application
    Filed: November 16, 2018
    Publication date: July 11, 2019
    Inventor: Marcus J. Mauro
  • Publication number: 20180185483
    Abstract: The present disclosure describes combination therapies comprising an antagonist of Programmed Death 1 receptor (PD-1) and a Listeria based strain that expresses prostate-tissue specific antigen (PSA), and the use of the combination therapies for the treatment of prostate cancer.
    Type: Application
    Filed: January 9, 2018
    Publication date: July 5, 2018
    Inventors: Robert PETIT, David J. MAURO, Rodolfo F. PERINI
  • Patent number: 9907849
    Abstract: The present disclosure describes combination therapies comprising an antagonist of Programmed Death 1 receptor (PD-1) and a Listeria based strain that expresses prostate-tissue specific antigen (PSA), and the use of the combination therapies for the treatment of prostate cancer.
    Type: Grant
    Filed: July 17, 2015
    Date of Patent: March 6, 2018
    Assignees: Advaxis, Inc., Merck Sharp & Dohme Corp.
    Inventors: Robert Petit, David J. Mauro, Rodolfo F. Perini
  • Publication number: 20170166641
    Abstract: The present disclosure describes combination therapies comprising an antagonist of Programmed Death 1 receptor (PD-1) and a VEGFR inhibitor, and the use of the combination therapies for the treatment of cancer, and in particular for treating cancers that express PD-L1.
    Type: Application
    Filed: February 3, 2015
    Publication date: June 15, 2017
    Inventors: Jean-Francois Andre Martini, Jamal Christo Tarazi, Rodolfo Fleury Perini, David J. Mauro
  • Publication number: 20160022814
    Abstract: The present disclosure describes combination therapies comprising an antagonist of Programmed Death 1 receptor (PD-1) and a Listeria based strain that expresses prostate-tissue specific antigen (PSA), and the use of the combination therapies for the treatment of prostate cancer.
    Type: Application
    Filed: July 17, 2015
    Publication date: January 28, 2016
    Inventors: Robert PETIT, David J. MAURO, Rodolfo F. PERINI
  • Publication number: 20140343273
    Abstract: The present invention pertains to methods for preparing enzymatically hydrolyzed starch for use as a stabilizing agent that include the steps of first gelatinizing a starch and next, hydrolyzing the gelatinized starch with an enzyme having endo-hydrolytic activity. The present invention also pertains to the resulting enzymatically hydrolyzed starch for use as a stabilizing agent within emulsions, beverages, food products and industrial products prepared using the enzymatically hydrolyzed starch.
    Type: Application
    Filed: July 25, 2014
    Publication date: November 20, 2014
    Applicant: CARGILL, INCORPORATED
    Inventors: Dirk FONTEYN, John R. HEIGIS, Joseph Bernard HOLTWICK, Catharina Hillagonda HOMSMA, David J. MAURO, Dirk Reimond PROVOOST, Wen-Juin SHIEH, Blair C. STEPHENS
  • Publication number: 20140115304
    Abstract: Computer implemented techniques are disclosed for identification of repeated binary strings and for storing those binary strings in order to compress code. The binary strings can be longer instructions, data, or addresses. A table of binary strings is generated based on repeated occurrences, and a reference index is provided for accessing specific entries within the table. An opcode uses a shorter string as an index through which to access the table. The longer string is executed when the longer string is an instruction. When the longer string is an address or data, the appropriate address or data are accessed.
    Type: Application
    Filed: October 18, 2012
    Publication date: April 24, 2014
    Applicant: SYNOPSYS, INC.
    Inventor: Marcus J. Mauro
  • Publication number: 20130000942
    Abstract: An electrical cable includes a sheath that envelops at least two internal conductors, and an indicia visible on the sheath is representative of the internal conductor.
    Type: Application
    Filed: August 27, 2012
    Publication date: January 3, 2013
    Applicant: ALLIED TUBE & CONDUIT CORPORATION
    Inventors: James C. Dollins, Anthony J. Mauro
  • Publication number: 20120270228
    Abstract: The present invention provides methods and compositions to facilitate determining whether an EGFR-expressing cancer in an individual is an EGFR inhibitor-responsive cancer, as well as methods for determining the likelihood that a patient having an EGFR-expressing cancer will exhibit a beneficial response to an EGFR inhibitor therapy. The methods generally involve determining a normalized expression level of a gene product that correlates with EGFR inhibitor responsiveness.
    Type: Application
    Filed: July 5, 2012
    Publication date: October 25, 2012
    Applicants: BRISTOL-MYERS SQUIBB COMPANY, GENOMIC HEALTH, INC.
    Inventors: Joffre B. Baker, Drew Watson, Tara Maddala, Steven Shak, David J. Mauro, Shirin K. Ford
  • Patent number: 8278554
    Abstract: An electrical cable includes a sheath that envelops at least two internal conductors, and an indicia visible on the sheath is representative of the internal conductor.
    Type: Grant
    Filed: December 10, 2008
    Date of Patent: October 2, 2012
    Assignee: WPFY, Inc.
    Inventors: James C. Dollins, Anthony J. Mauro
  • Patent number: 8273534
    Abstract: The present invention provides methods and compositions to facilitate determining whether an EGFR-expressing cancer in an individual is an EGFR inhibitor-responsive cancer, as well as methods for determining the likelihood that a patient having an EGFR-expressing cancer will exhibit a beneficial response to an EGFR inhibitor therapy. The methods generally involve determining a normalized expression level of a gene product that correlates with EGFR inhibitor responsiveness.
    Type: Grant
    Filed: May 13, 2009
    Date of Patent: September 25, 2012
    Assignees: Genomic Health, Inc., Bristol-Myers Squibb Company
    Inventors: Joffre B. Baker, Drew Watson, Tara Maddala, Steven Shak, David J. Mauro, Shirin K. Ford
  • Publication number: 20110052780
    Abstract: The present invention pertains to methods for preparing enzymatically hydrolyzed starch for use as a stabilizing agent that include the steps of first gelatinizing a starch and next, hydrolyzing the gelatinized starch with an enzyme having endo-hydrolytic activity. The present invention also pertains to the resulting enzymatically hydrolyzed starch for use as a stabilizing agent within emulsions, beverages, food products and industrial products prepared using the enzymatically hydrolyzed starch.
    Type: Application
    Filed: January 29, 2009
    Publication date: March 3, 2011
    Applicant: CARGILL, INCORPORATED
    Inventors: Dirk Fonteyn, John R. Heigis, Joseph Bernard Holtwick, Cathrina Hillagonda Homsma, David J. Mauro, Dirk Reimond Provoost, Wen-Juin Shieh, Blair C. Stephens
  • Patent number: 7745686
    Abstract: There is provided a fibrous absorbent article for absorbing body fluids made up of a fibrous material defining a structure suitable for absorbing the body fluids, and disposed within the structure an effective amount, so as to reduce Staphylococcus aureus bacterial growth and neutralize TSS toxin-1 within the vagina, of one or more antimicrobial agents and one or more finishing agents.
    Type: Grant
    Filed: November 2, 2001
    Date of Patent: June 29, 2010
    Assignee: Playtex Products, Inc.
    Inventors: Anthony J. Mauro, Mark E. Rosengarten, Irwin Butensky
  • Publication number: 20090298701
    Abstract: The present invention provides methods and compositions to facilitate determining whether an EGFR-expressing cancer in an individual is an EGFR inhibitor-responsive cancer, as well as methods for determining the likelihood that a patient having an EGFR-expressing cancer will exhibit a beneficial response to an EGFR inhibitor therapy. The methods generally involve determining a normalized expression level of a gene product that correlates with EGFR inhibitor responsiveness.
    Type: Application
    Filed: May 13, 2009
    Publication date: December 3, 2009
    Inventors: Joffre B. Baker, Drew Watson, Tara Maddala, Steven Shak, David J. Mauro, Shirin K. Ford
  • Publication number: 20090084575
    Abstract: An electrical cable includes a sheath that envelops at least two internal conductors, and an indicia visible on the sheath is representative of the internal conductor.
    Type: Application
    Filed: December 10, 2008
    Publication date: April 2, 2009
    Inventors: James C. Dollins, Anthony J. Mauro
  • Patent number: 7465878
    Abstract: An electrical cable includes a sheath that envelops at least two internal conductors, and an indicia visible on the sheath is representative of the internal conductor.
    Type: Grant
    Filed: August 18, 2004
    Date of Patent: December 16, 2008
    Assignee: WPFY, Inc.
    Inventors: James C. Dollins, Anthony J. Mauro
  • Publication number: 20080087843
    Abstract: A method of controllably changing an intrinsic property of a quantum dot by using a biological entity, either attached or in close proximity to the quantum dot, and changing the state of biological entity with a controllable mechanism. The change in state of the biological entity controllably changes the intrinsic property of the quantum dot. The photoluminescence emission of quantum dots can be controlled by the present method. The methods disclosed include controlling the magnitude of QD photoluminescence as well as turning the photoluminescence on/off. The methods disclosed include using the same biological control architecture to control other intrinsic QD properties such as charge state, magnetic or other property.
    Type: Application
    Filed: March 7, 2007
    Publication date: April 17, 2008
    Inventors: Igor Medintz, Hedi Mattoussi, Moungi Bawendi, J. Mauro, George Anderson, Thomas Pons