Patents by Inventor Jérôme BECKER

Jérôme BECKER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BROMIDE SOURCE FOR USE IN TREATING AUTISM SPECTRAL DISORDER
    Publication number: 20240398855
    Abstract: The present invention relates to a novel pharmaceutical use of bromide, i.e. the treatment of autism spectral disorder (ASD)).
    Type: Application
    Filed: June 4, 2024
    Publication date: December 5, 2024
    Inventors: Sébastien ROUX, Thierry PLOUVIER, Julie LE MERRER, Jérôme BECKER
  • METHODS FOR TREATING AUTISM SPECTRUM DISORDERS
    Publication number: 20240366539
    Abstract: Autism Spectrum Disorders (ASD) are neurodevelopmental disorders whose diagnosis relies on deficient social interaction and communication together with repetitive behavior. To date, no pharmacological treatment has been approved that ameliorates social behavior in patients with ASD. Based on the excitation/inhibition imbalance theory of autism, the Inventors hypothesized that bromide ions, long used as an antiepileptic medication, could relieve core symptoms of ASD. They evaluated the effects of chronic sodium bromide (NaBr) administration on autistic-like symptoms in three genetic mouse models of autism: Oprm1?/?, Fmr1?/? and Shank3?ex13-16?/? mice. They showed that chronic NaBr treatment relieved autistic-like behaviors in these three models. In Oprm1?/? mice, these beneficial effects were superior to those of chronic bumetanide administration.
    Type: Application
    Filed: September 2, 2022
    Publication date: November 7, 2024
    Inventors: Jérôme BECKER, Julie LE MERRER
  • Bromide source for use in treating autism spectral disorder
    Patent number: 12036237
    Abstract: The present invention relates to a novel pharmaceutical use of bromide, i.e. the treatment of autism spectral disorder (ASD).
    Type: Grant
    Filed: April 20, 2023
    Date of Patent: July 16, 2024
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT, CNRS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE STRASBOURG
    Inventors: Sébastien Roux, Thierry Plouvier, Julie Le Merrer, Jérôme Becker
  • BROMIDE SOURCE FOR USE IN TREATING AUTISM SPECTRAL DISORDER
    Publication number: 20230256009
    Abstract: The present invention relates to a novel pharmaceutical use of bromide, i.e. the treatment of autism spectral disorder (ASD).
    Type: Application
    Filed: April 20, 2023
    Publication date: August 17, 2023
    Inventors: Sébastien ROUX, Thierry PLOUVIER, Julie LE MERRER, Jérôme BECKER
  • Bromide source for use in treating autism spectral disorder
    Patent number: 11666599
    Abstract: The present invention relates to a novel pharmaceutical use of bromide, i.e. the treatment of autism spectral disorder (ASD).
    Type: Grant
    Filed: November 28, 2017
    Date of Patent: June 6, 2023
    Assignees: INSERM, INTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, INRA, INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE, CNRS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE STRASBOURG
    Inventors: Sébastien Roux, Thierry Plouvier, Julie Le Merrer, Jérôme Becker
  • BROMIDE SOURCE FOR USE IN TREATING AUTISM SPECTRAL DISORDER
    Publication number: 20210106613
    Abstract: The present invention relates to a novel pharmaceutical use of bromide, i.e. the treatment of autism spectral disorder (ASD).
    Type: Application
    Filed: November 28, 2017
    Publication date: April 15, 2021
    Inventors: Sébastien ROUX, Thierry PLOUVIER, Julie LE MERRER, Jérôme BECKER