Patents by Inventor Jérôme BRETON

Jérôme BRETON has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NEW COMPOSITIONS AND METHODS OF TREATING COVID-19 DISEASE
    Publication number: 20230157994
    Abstract: A method of treating COVID-19 in a patient. The patient may be in moderate to advanced stages of COVID-19 infection. The method includes administering to the patient a therapeutically effective amount of at least one antagonist or inhibitor of chemokine receptor CXCR4. The at least one antagonist or inhibitor of chemokine receptor CXCR4 is distinct from hydroxychloroquine.
    Type: Application
    Filed: May 5, 2021
    Publication date: May 25, 2023
    Applicants: 4LIVING BIOTECH, UNIVERSITE DE BORDEAUX, CENTRE HOSPITALIER DE BORDEAUX, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM, INSTITUT PASTEUR DE LILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE LILLE
    Inventors: Patrick BERGER, Isabelle DUPIN, Renaud PREVEL, Chloé JAMES, Pierre-Olivier GIRODET, Keren BISMUTH, Revital RATTENBACH, Jérôme BRETON, Francois TROTTEIN, Valentin SENCIO
  • Bioremediation of nitrate contaminated groundwater
    Patent number: 6599425
    Abstract: The invention disclosed relates to a method and apparatus for the denitrification of groundwater in situ in an aquifer under substantially anaerobic conditions, the method comprising (a) providing a network, including an extraction well for removal of groundwater from the aquifer and a plurality of injection wells for returning groundwater to the aquifer, the injection wells being arranged in a line substantially perpendicular to the direction of groundwater flow, the extraction well being located downstream or upstream of the line of injection wells, and the spacing of the wells and the number of injection wells being determined by the mathematical relationship J = C p + nC 1 W → min
    Type: Grant
    Filed: June 27, 2001
    Date of Patent: July 29, 2003
    Assignee: National Research Council of Canada
    Inventors: Boris Tartakovsky, Serge Guiot, Jerome Breton, Serge Delisle
  • Bioremediation of nitrate contaminated groundwater
    Publication number: 20020020664
    Abstract: The invention disclosed relates to a method and apparatus for the denitrification of groundwater in situ in an aquifer under substantially anaerobic conditions, the method comprising
    Type: Application
    Filed: June 27, 2001
    Publication date: February 21, 2002
    Inventors: Boris Tartakovsky, Serge Guiot, Jerome Breton, Serge Delisle
  • Recombinant KAT enzyme and process for its preparation
    Patent number: 6136572
    Abstract: Disclosed are isolated DNAs encoding a kynurenine aminotransferase selected from the group consisting of:(a) isolated DNA sequences which encode rat KAT;(b) an isolated DNA sequence which hybridizes to isolated DNA sequences of (a) above and which encodes a mammalian KAT enzyme; and(c) an isolated DNA sequence differing from the isolated DNA sequences of (a) and (b) above in codon sequence due to the degeneracy of the genetic code, and which encodes a KAT enzyme.Vectors and host cells containing the same, oligonucleotide probes for identifying kynurenine aminotransferase, and isolated and purified kynurenine aminotransferase are also disclosed.
    Type: Grant
    Filed: April 1, 1997
    Date of Patent: October 24, 2000
    Assignees: University of Maryland at Baltimore, Pharmacia & Upjohn S.P.A.
    Inventors: Luca Benatti, Jerome Breton, Carmela Speciale, Etsuo Okuno, Robert Schwarcz, Monica Mosca
  • Recombinant kat enzyme from rat
    Patent number: 5817496
    Abstract: Disclosed are isolated DNAs encoding a kynurenine aminotransferase selected from the group consisting of: (a) an isolated DNA sequence which encodes rat KAT; (b) an isolated DNA sequence which hybridizes to the isolated DNA sequence of (a) above and which encodes a KAT enzyme; and (c) an isolated DNA sequence differing from the isolated DNA sequences of (a) and (b) above in codon sequence due to the degeneracy of the genetic code, and which encodes a KAT enzyme. Also disclosed are vectors and host cells containing the same; oligonucleotide probes for identifying kynurenine aminotransferase; and isolated and purified kynurenine aminotransferase.
    Type: Grant
    Filed: July 7, 1994
    Date of Patent: October 6, 1998
    Assignees: Pharmacia & UpJohn S.P.A., University of Maryland at Baltimore
    Inventors: Luca Benatti, Jerome Breton, Carmela Speciale, Etsuo Okuno, Robert Schwarcz, Monica Mosca