Patents by Inventor Jérôme Michel Claude Fortin

Jérôme Michel Claude Fortin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted indoline derivatives as dengue viral replication inhibitors
    Patent number: 11795149
    Abstract: The present invention concerns substituted indoline derivatives, methods to prevent or treat dengue viral infections by using said compounds and also relates to said compounds for use as a medicine, more preferably for use as a medicine to treat or prevent dengue viral infections. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the compounds, to the compositions or preparations for use as a medicine, more preferably for the prevention or treatment of dengue viral infections. The invention also relates to processes for preparation of the compounds.
    Type: Grant
    Filed: June 16, 2022
    Date of Patent: October 24, 2023
    Assignees: Janssen Pharmaceuticals, Inc., Katholieke Universiteit Leuven
    Inventors: Jean-François Bonfanti, Bart Rudolf Romanie Kesteleyn, Dorothée Alice Marie-Eve Bardiot, Arnaud Didier M Marchand, Erwin Coesemans, Jérôme Michel Claude Fortin, Guillaume Jean Maurice Mercey, Pierre Jean-Marie Bernard Raboisson
  • Macrocyclic deaza-purinones for the treatment of viral infections
    Patent number: 11702426
    Abstract: This invention relates to macrocyclic deaza-purinones derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Grant
    Filed: October 27, 2020
    Date of Patent: July 18, 2023
    Assignee: JANSSEN SCIENCES IRELAND UNLIMITED COMPANY
    Inventors: Jean-François Bonfanti, Jérôme Michel Claude Fortin, Philippe Muller, Frédéric Marc Maurice Doublet, Pierre Jean-Marie Bernard Raboisson, Eric Pierre Alexandre Arnoult
  • MACROCYCLIC FLU ENDONUCLEASE INHIBITORS
    Publication number: 20230002409
    Abstract: The present invention relates to macrocyclic pyridotriazine derivatives and the prodrugs thereof, and the pharmaceutically acceptable salts, solvates or polymorph thereof, and the use of such compounds as a medicament, in particular in the prevention and/or treatment of viral infections caused by viruses belonging to the Orthomyxoviridae family. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the compounds, and to the compositions or preparations for use as a medicament, more preferably for the prevention or treatment of viral infections caused by viruses belonging to the Orthomyxoviridae family.
    Type: Application
    Filed: March 15, 2022
    Publication date: January 5, 2023
    Inventors: Robert Than HENDRICKS, Antitsa Dimitrova STOYCHEVA, Jean-François BONFANTI, Pierre Jean-Marie Bernard RABOISSON, Jérôme Michel Claude FORTIN, Guillaume Jean Maurice MERCEY
  • SUBSTITUTED INDOLINE DERIVATIVES AS DENGUE VIRAL REPLICATION INHIBITORS
    Publication number: 20220340522
    Abstract: The present invention concerns substituted indoline derivatives, methods to prevent or treat dengue viral infections by using said compounds and also relates to said compounds for use as a medicine, more preferably for use as a medicine to treat or prevent dengue viral infections. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the compounds, to the compositions or preparations for use as a medicine, more preferably for the prevention or treatment of dengue viral infections. The invention also relates to processes for preparation of the compounds.
    Type: Application
    Filed: June 16, 2022
    Publication date: October 27, 2022
    Applicants: Janssen Pharmaceuticals, Inc., Katholieke Universiteit Leuven
    Inventors: Jean-François Bonfanti, Bart Rudolf Romanie Kesteleyn, Dorothée Alice Marie-Eve Bardiot, Arnaud Didier M Marchand, Erwin Coesemans, Jérôme Michel Claude Fortin, Guillaume Jean Maurice Mercey, Pierre Jean-Marie Bernard Raboisson
  • Substituted indoline derivatives as dengue viral replication inhibitors
    Patent number: 11407715
    Abstract: The present invention concerns substituted indoline derivatives, methods to prevent or treat dengue viral infections by using said compounds and also relates to said compounds for use as a medicine, more preferably for use as a medicine to treat or prevent dengue viral infections. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the compounds, to the compositions or preparations for use as a medicine, more preferably for the prevention or treatment of dengue viral infections. The invention also relates to processes for preparation of the compounds.
    Type: Grant
    Filed: May 18, 2018
    Date of Patent: August 9, 2022
    Assignees: Janssen Pharmaceuticals, Inc., Katholieke Universiteit Leuven
    Inventors: Jean-François Bonfanti, Bart Rudolf Romanie Kesteleyn, Dorothée Alice Marie-Eve Bardiot, Arnaud Didier M Marchand, Erwin Coesemans, Jérôme Michel Claude Fortin, Guillaume Jean Maurice Mercey, Pierre Jean-Marie Bernard Raboisson
  • PURINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS
    Publication number: 20220235052
    Abstract: The present invention relates to purine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Application
    Filed: August 30, 2021
    Publication date: July 28, 2022
    Inventors: Jean-François BONFANTI, Frédéric Marc Maurice DOUBLET, Werner EMBRECHTS, Jérôme Michel Claude FORTIN, David Craig MC GOWAN, Philippe MULLER, Pierre Jean-Marie Bernard RABOISSON
  • Macrocyclic flu endonuclease inhibitors
    Patent number: 11312727
    Abstract: The present invention relates to macrocyclic pyridotriazine derivatives of formula (I) and the pharmaceutically acceptable salts, solvates or polymorph thereof, and the use of such compounds as a medicament, in particular in the prevention and/or treatment of viral infections caused by viruses belonging to the Orthomyxoviridae family. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the compounds, and to the compositions or preparations for use as a medicament, more preferably for the prevention or treatment of viral infections caused by viruses belonging to the Orthomyxoviridae family.
    Type: Grant
    Filed: October 9, 2019
    Date of Patent: April 26, 2022
    Assignee: Janssen BioPharma, Inc.
    Inventors: Robert Than Hendricks, Antitsa Dimitrova Stoycheva, Jean-François Bonfanti, Pierre Jean-Marie Bernard Raboisson, Jérôme Michel Claude Fortin, Guillaume Jean Maurice Mercey
  • Purine derivatives for the treatment of viral infections
    Patent number: 11104678
    Abstract: The present invention relates to purine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Grant
    Filed: May 6, 2019
    Date of Patent: August 31, 2021
    Assignee: JANSSEN SCIENCES IRELAND UNLIMITED COMPANY
    Inventors: Jean-François Bonfanti, Frédéric Marc Maurice Doublet, Werner Embrechts, Jérôme Michel Claude Fortin, David Craig McGowan, Pierre Jean-Marie Bernard Raboisson
  • MACROCYCLIC DEAZA-PURINONES FOR THE TREATMENT OF VIRAL INFECTIONS
    Publication number: 20210122760
    Abstract: This invention relates to macrocyclic deaza-purinones derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Application
    Filed: October 27, 2020
    Publication date: April 29, 2021
    Inventors: Jean-François BONFANTI, Jérôme Michel Claude FORTIN, Philippe MULLER, Frédéric Marc Maurice DOUBLET, Pierre Jean-Marie Bernard RABOISSON, Eric Pierre Alexandre ARNOULT
  • Macrocyclic deaza-purinones for the treatment of viral infections
    Patent number: 10829494
    Abstract: This invention relates to macrocyclic deaza-purinones derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Grant
    Filed: April 19, 2019
    Date of Patent: November 10, 2020
    Assignee: JANSSEN SCIENCES IRELAND UNLIMITED COMPANY
    Inventors: Jean-François Bonfanti, Jérôme Michel Claude Fortin, Philippe Muller, Frédéric Marc Maurice Doublet, Pierre Jean-Marie Bernard Raboisson, Eric Pierre Alexandre Arnoult
  • Macrocyclic purines for the treatment of viral infections
    Patent number: 10822349
    Abstract: This invention relates macrocyclic purine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Grant
    Filed: May 6, 2019
    Date of Patent: November 3, 2020
    Assignee: JANSSEN SCIENCES IRELAND UNLIMITED COMPANY
    Inventors: Jean-François Bonfanti, Jérôme Michel Claude Fortin, Frédéric Marc Maurice Doublet, Pierre Jean-Marie Bernard Raboisson, Eric Pierre Alexandre Arnoult
  • PURINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS
    Publication number: 20190359614
    Abstract: The present invention relates to purine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Application
    Filed: May 6, 2019
    Publication date: November 28, 2019
    Inventors: Jean-François BONFANTI, Frédéric Marc Maurice DOUBLET, Werner EMBRECHTS, Jérôme Michel Claude FORTIN, David Craig MC GOWAN, Pierre Jean-Marie Bernard RABOISSON
  • MACROCYCLIC DEAZA-PURINONES FOR THE TREATMENT OF VIRAL INFECTIONS
    Publication number: 20190330222
    Abstract: This invention relates to macrocyclic deaza-purinones derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Application
    Filed: April 19, 2019
    Publication date: October 31, 2019
    Inventors: Jean-François BONFANTI, Jérôme Michel Claude FORTIN, Philippe MULLER, Frédéric Marc Maurice DOUBLET, Pierre Jean-Marie Bernard RABOISSON, Eric Pierre Alexandre ARNOULT
  • MACROCYCLIC PURINES FOR THE TREATMENT OF VIRAL INFECTIONS
    Publication number: 20190330234
    Abstract: This invention relates macrocyclic purine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Application
    Filed: May 6, 2019
    Publication date: October 31, 2019
    Inventors: Jean-François BONFANTI, Jérôme Michel Claude FORTIN, Frédéric Marc Maurice DOUBLET, Pierre Jean-Marie Bernard RABIOSSON, Eric Pierre Alexandre ARNOULT
  • Purine derivatives for the treatment of viral infections
    Patent number: 10280167
    Abstract: The present invention relates to purine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Grant
    Filed: January 30, 2017
    Date of Patent: May 7, 2019
    Assignee: Janssen Sciences Ireland UC
    Inventors: Jean-François Bonfanti, Frédéric Marc Maurice Doublet, Werner Embrechts, Jérôme Michel Claude Fortin, David Craig McGowan, Philippe Muller, Pierre Jean-Marie Bernard Raboisson
  • Macrocyclic purines for the treatment of viral infections
    Patent number: 10280180
    Abstract: This invention relates macrocyclic purine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Grant
    Filed: July 12, 2013
    Date of Patent: May 7, 2019
    Assignee: Janssen Sciences Ireland UC
    Inventors: Jean-Francois Bonfanti, Jerome Michel Claude Fortin, Philippe Muller, Frederic Marc Maurice Doublet, Pierre Jean-Marie Bernard Raboisson, Eric Pierre Alexandre Arnoult
  • Macrocyclic deaza-purinones for the treatment of viral infections
    Patent number: 10266543
    Abstract: This invention relates to macrocyclic deaza-purinones derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Grant
    Filed: March 28, 2014
    Date of Patent: April 23, 2019
    Assignee: Janssen Sciences Ireland UC
    Inventors: Jean-François Bonfanti, Jérôme Michel Claude Fortin, Philippe Muller, Frédéric Marc Maurice Doublet, Pierre Jean-Marie Bernard Raboisson, Eric Pierre Alexandre Arnoult
  • Pyrimidine derivatives for the treatment of bacterial diseases
    Patent number: 10221157
    Abstract: The present invention relates to novel compounds of formula I: or a pharmaceutically acceptable salt thereof, wherein the integers are as defined in the description. The claimed compounds are useful for the treatment of a bacterial infection. Also claimed is a composition comprising a pharmaceutically acceptable carrier and, as active ingredient, a therapeutically effective amount of the claimed compounds, the use of the claimed compounds or compositions for the manufacture of a medicament for the treatment of a bacterial infection and a process for preparing the claimed compounds.
    Type: Grant
    Filed: August 4, 2017
    Date of Patent: March 5, 2019
    Assignee: Janssen Pharmaceutica NV
    Inventors: Jean-Francois Bonfanti, Philippe Muller, Frederic Marc Maurice Doublet, Jerome Michel Claude Fortin, Nacer Lounis
  • PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF BACTERIAL DISEASES
    Publication number: 20170334880
    Abstract: The present invention relates to novel compounds of formula I: or a pharmaceutically acceptable salt thereof, wherein the integers are as defined in the description. The claimed compounds are useful for the treatment of a bacterial infection. Also claimed is a composition comprising a pharmaceutically acceptable carrier and, as active ingredient, a therapeutically effective amount of the claimed compounds, the use of the claimed compounds or compositions for the manufacture of a medicament for the treatment of a bacterial infection and a process for preparing the claimed compounds.
    Type: Application
    Filed: August 4, 2017
    Publication date: November 23, 2017
    Inventors: Jean-Francois BONFANTI, Philippe MULLER, Frederic Marc Maurice DOUBLET, Jerome Michel Claude FORTIN, Nacer LOUNIS
  • PURINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS
    Publication number: 20170283419
    Abstract: The present invention relates to purine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Application
    Filed: January 30, 2017
    Publication date: October 5, 2017
    Applicant: JANSSEN SCIENCES IRELAND UC
    Inventors: Jean-François BONFANTI, Frédéric Marc Maurice DOUBLET, Werner EMBRECHTS, Jérôme Michel Claude FORTIN, David Craig MC GOWAN, Philippe MULLER, Pierre Jean-Marie Bernard RABOISSON