Patents by Inventor J. Regino Perez-Polo

J. Regino Perez-Polo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8399421
    Abstract: The present invention is drawn to treatment of neuropathic pain due to spinal cord injury. In this regard, the present invention discloses methods and composition to treat neuropathic pain.
    Type: Grant
    Filed: March 31, 2008
    Date of Patent: March 19, 2013
    Assignee: The Board of Regents of the University of Texas System
    Inventor: J. Regino Perez-Polo
  • Publication number: 20100292278
    Abstract: The present invention provides a method of treating a vascular disease or injury in an individual in need of such treatment, comprising the step of administering a compound or composition that down-regulates or decreases the activity of microRNA-29 in the individual. Also provided is a method of down-regulating or decreasing the activity of microRNA-29 in an individual in need of such treatment, comprising the step of administering a PPAR-? agonist compound or PPAR-? agonist containing composition that down-regulates or decreases the activity of microRNA-29 in the individual. Further provided is a method of treating a vascular disease or injury in an individual in need of such treatment, comprising the step of administering a microRNA-29 antagonist that down-regulates or decreases the activity of microRNA-29 in said individual.
    Type: Application
    Filed: May 17, 2010
    Publication date: November 18, 2010
    Inventors: Yochai Birnbaum, Yumei Ye, J.Regino Perez-Polo
  • Publication number: 20080242634
    Abstract: The present invention is drawn to treatment of neuropathic pain due to spinal cord injury. In this regard, the present invention discloses methods and composition to treat neuropathic pain.
    Type: Application
    Filed: March 31, 2008
    Publication date: October 2, 2008
    Inventor: J. Regino Perez-Polo
  • Patent number: 5712160
    Abstract: The present invention involves peptides derived from nerve growth factor receptor protein. Such peptides are characterized by competing for NGF binding to NGF receptor at high concentrations while accentuating NGF binding at low concentrations. Preferred peptides include Cys-Glu-Glu-Cys-Pro-Glu-OH, Asn-Thr-Val-Cys-Glu-Glu-Cys-Pro-Glu-OH, Gln-Asp-Lys-Gln-Asn-Thr-Val-Cys-Glu-Glu-Cys-Pro-Glu-OH and Cys-Gln-Asp-Lys-Gln-Asn-Thr-Val-Cys-Glu-Glu-Cys-Pro-Glu-OH.
    Type: Grant
    Filed: December 11, 1995
    Date of Patent: January 27, 1998
    Assignee: Board of Regents, The University of Texas System
    Inventor: J. Regino Perez-Polo
  • Patent number: 5475088
    Abstract: The present invention involves peptides derived from nerve growth factor receptor protein. Such peptides are characterized by competing for NGF binding to NGF receptor at high concentrations while accentuating NGF binding at low concentrations. Preferred peptides include Cys-Glu-Glu-Cys-Pro-Glu-OH, Asn-Thr-Val-Cys-Glu-Glu-Cys-Pro-Glu-OH, Gln-Asp-Lys-Gln-Asn-Thr-Val-Cys-Glu-Glu-Cys-Pro-Glu-OH and Cys-Gln-Asp-Lys-Gln-Asn-Thr-Val-Cys-Glu-Glu-Cys-Pro-Glu-OH.
    Type: Grant
    Filed: March 10, 1994
    Date of Patent: December 12, 1995
    Assignee: Board of Regents, The University of Texas System
    Inventor: J. Regino Perez-Polo