Patents by Inventor Jörg Bauer
Jörg Bauer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20110162105Abstract: The present invention relates to nucleic acids derived from Drechslera tritici-repentis, Cylindorcarpon herteronema, Diploida natalensis, Stagonospora nodorum, Microdochium nivalae and Periplaneta americana. The invention also relates to the individual coding sequences and to proteins encoded by these sequences in combination with other sequences as well as to a process for converting oleic acid to linoleic acid to Iinoleic acid and the production of arachidonic acid, eicosapentaenoic acid and/or docosahexaenoic acid in a plant.Type: ApplicationFiled: August 25, 2009Publication date: June 30, 2011Applicants: BASF Plant Science GmbH, Bioriginal Food & Science Corp.Inventors: Jörg Bauer, Toralf Senger, Thorsten Zank, Xiao Qiu, Guohai Wu
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Publication number: 20110138490Abstract: The present invention relates to a polynucleotide from Emiliana huxleyi which codes for a desaturase and which can be employed for the recombinant production of polyunsaturated fatty acids. The invention furthermore relates to vectors, host cells and transgenic nonhuman organisms which comprise the polynucleotide according to the invention, and to the polypeptides encoded by the polynucleotide. The invention furthermore relates to antibodies against the polypeptide according to the invention. Finally, the invention also relates to production methods for the polyunsaturated fatty acids and for oil, lipid and fatty acid compositions and to their use as drugs, cosmetics, foodstuffs, feedstuffs, preferably fish food, or food supplements.Type: ApplicationFiled: April 29, 2009Publication date: June 9, 2011Inventors: Joerg Bauer, Johnathan A. Napier, Olga Sayanova
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Publication number: 20110113510Abstract: The present invention is concerned with means and methods for allowing tissue specific and, in particular, seed specific expression of genes. The present invention, accordingly, relates to a polynucleotide comprising an expression control sequence which allows seed specific expression of a nucleic acid of interest being operatively linked thereto. Moreover, the present invention contemplates vectors, host cells, non-human transgenic organisms comprising the aforementioned polynucleotide as well as methods and uses of such a polynucleotide.Type: ApplicationFiled: June 30, 2009Publication date: May 12, 2011Applicant: BASF Plant Science GmbHInventors: Jörg Bauer, Toralf Senger
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Publication number: 20110088123Abstract: The invention provides isolated nucleic acid molecules which encode novel fatty acid dehydratase family members. The invention also provides recombinant expression vectors containing dehydratase nucleic acid molecules, host cells into which the expression vectors have been introduced, and methods for large-scale production of long chain polyunsaturated fatty acids (LCPUFAs), e.g., SDA, EPA and DHA.Type: ApplicationFiled: June 2, 2009Publication date: April 14, 2011Applicants: BASF Plant Science GmbH, Bioriginal Food & Science Corp.Inventors: Jörg Bauer, Xiao Qiu, Patricia Vrinten
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Publication number: 20110055972Abstract: Isolated nucleic acids and proteins associated with lipid and sugar metabolism regulation are provided. In particular, lipid metabolism proteins (LMP) and encoding nucleic acids originating from Arabidopsis thaliana, Brassica napus, and Physcomitrella patens are provided. The nucleic acids and proteins are used in methods of producing transgenic plants and modulating levels of seed storage compounds. Preferably, the seed storage compounds are lipids, fatty acids, starches, or seed storage proteins.Type: ApplicationFiled: November 10, 2010Publication date: March 3, 2011Applicant: BASF PLANT SCIENCE GMBHInventors: VOLKER MITTENDORF, HEIKO A. HAERTEL, JÖRG BAUER, OLIVER OSWALD
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Publication number: 20110039010Abstract: The invention relates to a plant seed oil, comprising arachidonic acid comprising approximately 7 to approximately 26 percent by weight of the total fatty acid content, the ratio of the percentages by weight of arachidonic acid to gamma-linolenic acid being approximately 1:1 to approximately 5:1 and the ratio of the percentages by weight of arachidonic acid to dihomo-gamma-linolenic acid being approximately 1:1 to approximately 5:1. The invention additionally relates to processes for the production of this plant seed oil and formulations and uses of the plant seed oil. In particular, the invention also makes available foodstuffs and baby food that contain the plant seed oil mentioned.Type: ApplicationFiled: April 23, 2009Publication date: February 17, 2011Applicant: BASF Plant Science GmbHInventors: Dietrich Rein, Toralf Senger, Jörg Bauer
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Publication number: 20110023185Abstract: The invention relates to a process for the production of long-chain polyunsaturated fatty acids in an organism by introducing, into the organism, nucleic acids coding for polypeptides with acyltransferase activity. These nucleic acid sequences, if appropriate together with further nucleic acid sequences coding for polypeptides of the fatty acid or lipid metabolism biosynthesis, can advantageously be expressed in the organism. Furthermore, the invention relates to a method for the production of oils and/or triacylglycerides with an elevated content of long-chain polyunsaturated fatty acids. The invention furthermore relates to the nucleic acid sequences, and constructs, vectors and organisms comprising the nucleic acid sequences. A further part of the invention relates to oils, lipids and/or fatty acids produced by the process according to the invention and to their use.Type: ApplicationFiled: July 28, 2010Publication date: January 27, 2011Applicant: UNIVERSITY OF BRISTOLInventors: ANDREAS RENZ, JÖRG BAUER, MARGIT FRENTZEN, NURSEN SÖZER, STOBART KEITH, THOMAS FRASER, COLIN M. LAZARUS, BAOXIU QI, AMINE ABBADI, ERNST HEINZ
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Patent number: 7871804Abstract: The invention relates to a method for producing polyunsaturated fatty acids in an organism, according to which nucleic acids coding for polypeptides with an acyl-CoA:lysophospholipid-acyltransferase activity are introduced into the organism. Advantageously, the nucleic acid sequences can be expressed in the transgenic organism optionally together with other nucleic acid sequences coding for polypeptides of the fatty acid or lipid metabolism. The invention also relates to the inventive nucleic acid sequences, nucleic acid constructs containing the inventive nucleic acid sequences, vectors containing the inventive nucleic acid sequences and/or the nucleic acid constructs, and transgenic organisms containing the nucleic acid sequences, nucleic acid constructs and/or vectors. The invention further relates to oils, lipids and/or fatty acids produced according to the inventive method, and to the use of the same.Type: GrantFiled: December 20, 2005Date of Patent: January 18, 2011Assignee: BASF Plant Science GmbHInventors: Petra Cirpus, Jörg Bauer, Ernst Heinz, Amine Abbadi, Jelena Kirsch
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Patent number: 7858845Abstract: Isolated nucleic acids and proteins associated with lipid and sugar metabolism regulation are provided. In particular, lipid metabolism proteins (LMP) and encoding nucleic acids originating from Arabidopsis thaliana, Brassica napus, and Physcomitrella patens are provided. The nucleic acids and proteins are used in methods of producing trangenic plants and modulating levels of seed storage compounds. Preferably, the seed storage compounds are lipids, fatty acids, starches, or seed storage proteins.Type: GrantFiled: August 4, 2003Date of Patent: December 28, 2010Assignee: BASF Plant Science GmbHInventors: Volker Mittendorf, Heiko A. Haertel, Joerg Bauer, Oliver Oswald
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Patent number: 7855321Abstract: The present invention relates to a process for the production of long-chain polyunsaturated fatty acids in an organism by introducing, into the organism, nucleic acids which code for polypeptides with acyl transferase activity. These nucleic acid sequences, if appropriate together with further nucleic acid sequences which code for polypeptides of the fatty acid or lipid metabolism biosynthesis, can advantageously be expressed in the organism. Furthermore, the invention relates to a method for the production of oils and/or triacylglycerides with an elevated content of long-chain polyunsaturated fatty acids. The invention furthermore relates to the nucleic acid sequences, nucleic acid constructs, vectors and organisms comprising the nucleic acid sequences according to the invention, vectors comprising the nucleic acid sequences and/or the nucleic acid constructs and to transgenic organisms comprising the abovementioned nucleic acid sequences, nucleic acid constructs and/or vectors.Type: GrantFiled: March 26, 2004Date of Patent: December 21, 2010Assignee: University of BristolInventors: Andreas Renz, Jörg Bauer, Margit Frentzen, Nursen Sözer, Stobart Keith, Thomas Fraser, Colin M. Lazarus, Baoxiu Qi, Amine Abbadi, Ernst Heinz
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Patent number: 7842852Abstract: The present invention relates to a method for increasing the content of polyunsaturated long-chain fatty acids in an organism by introducing nucleic acids coding for polypeptides or proteins exhibiting a phospholipase, ketoacyl-CoA reductase and/or dehydratase activity. The present invention also provides nucleic acid sequences coding for polypeptides with enzyme activities of a phospholipase, ketoacyl-CoA reductase and/or dehydratase, and nucleic acid constructs, vectors and organisms containing the nucleic acid sequences according to the present invention. A further part of the present invention relates to oils, lipids and/or fatty acids produced according to the method of the present invention and the use thereof. Furthermore, the present invention relates to unsaturated fatty acids and triglycerides having an increased content of unsaturated fatty acids and the use thereof.Type: GrantFiled: July 15, 2005Date of Patent: November 30, 2010Assignee: BASF Plant Science GmbHInventors: Petra Cirpus, Jörg Bauer, Xiao Qiu, Patricia Vrinten
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Publication number: 20100263088Abstract: The present invention is concerned with means and methods for allowing tissue specific and, in particular, seed specific expression of genes. The present invention, accordingly, relates to a polynucleotide comprising an expression control sequence which allows seed specific expression of a nucleic acid of interest being operatively linked thereto. Moreover, the present invention contemplates vectors, host cells, non-human transgenic organisms comprising the aforementioned polynucleotide as well as methods and uses of such a polynucleotide.Type: ApplicationFiled: December 15, 2008Publication date: October 14, 2010Inventors: Jörg Bauer, Tom Wetjen, Xiao Qiu, Guohai Wu
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Publication number: 20100227924Abstract: The invention relates to a method for producing eicosapentanoic acid, docosapentanoic acid and/or docohexanoic acid in transgenic plants. According to said method, the plant is provided with at least one nucleic acid sequence coding for a polypeptide with a ?6 desaturase activity, at least one nucleic acid sequence coding for a polypeptide with a ?6 elongase activity, at least one nucleic acid sequence coding for a polypeptide with a ?5 desaturase activity, and at least one nucleic acid sequence coding for a polypeptide with a ?5 elongase activity, the nucleic acid sequence coding for a polypeptide with a ?5 elongase activity being modified in relation to the nucleic acid sequence in the organism from which the sequence originates, such that it is adapted to the codon use in at least one type of plant. For the production of docosahexanoic acid, at least one nucleic acid sequence coding for a polypeptide with a ?4 desaturase activity is also introduced into the plant.Type: ApplicationFiled: February 21, 2007Publication date: September 9, 2010Applicant: BASF Plant Science GmbHInventors: Petra Cirpus, Jörg Bauer, Xiao Qiu, Guohai Wu, Bifang Cheng, Martin Truksa, Tom Wetjen
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Publication number: 20100212034Abstract: The present invention relates to nucleic acid sequences coding for polypeptides with ?-3-desaturase activity. The invention furthermore relates to nucleic acid constructs, vectors and organisms comprising at least one nucleic acid sequence according to the invention, at least one vector comprising the nucleic acid sequence and/or the nucleic acid constructs, and transgenic organisms comprise the abovementioned nucleic acid sequences, nucleic acid constructs and/or vectors.Type: ApplicationFiled: April 27, 2010Publication date: August 19, 2010Applicant: BASF Plant Science GmbHInventors: Petra Cirpus, Jörg Bauer, Thorsten Zank, Ernst Heinz
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Patent number: 7777098Abstract: The present invention relates to a process for production of unsaturated ?-3-fatty acids and to a process for production of triglycerides with an elevated content of unsaturated fatty acids, especially of ?-3-fatty acids having more than three double bonds. The invention relates to the production of a transgenic organism, preferably of a transgenic plant or of a transgenic microorganism, with an elevated content of unsaturated ?-3-fatty acids, oils or lipids having ?-3-double bonds as the result of the expression of an ?-3-desaturase from fungi of the family Pythiaceae such as the genus Phytophtora, for example of the genus and species Phytophtora infestans.Type: GrantFiled: February 23, 2005Date of Patent: August 17, 2010Assignee: BASF Plant Science GmbHInventors: Petra Cirpus, Jörg Bauer, Thorsten Zank, Ernst Heinz
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Publication number: 20100199365Abstract: The present invention relates to polynucleotides from Helobdella robusta, Laccaria bicolor, Lottia gigantea, Microcoleus chthonoplastes, Monosiga brevicollis, Mycosphaerella fijiensis, Mycospaerella graminicola, Naegleria gruberi, Nectria haematococca, Nematostella vectensis, Phycomyces blakesleeanus, Trichoderma resii, Physcomitrella patens, Postia placenta, Selaginella moellendorffii and Microdochium nivale, which code for desaturases and which can be employed for the recombinant production of polyunsaturated fatty acids. The invention furthermore relates to vectors, host cells and transgenic nonhuman organisms which comprise the polynucleotides according to the invention, and to the polypeptides encoded by the polynucleotides. The invention furthermore relates to antibodies against the polypeptides according to the invention.Type: ApplicationFiled: July 30, 2008Publication date: August 5, 2010Applicant: BASF Plant Science GmbHInventors: Toralf Senger, Jörg Bauer
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Publication number: 20100192238Abstract: The present invention relates to polynucleotides from Pythium irregulare, Rhizopus oryzae and Euglena gracilis which code for elongases and which can be employed for the recombinant production of polyunsaturated fatty acids. The invention furthermore relates to vectors, host cells and transgenic nonhuman organisms which comprise the polynucleotides according to the invention, and to the polypeptides encoded by the polynucleotides. The invention furthermore relates to antibodies against the polypeptides according to the invention. Finally, the invention also relates to production processes for the polyunsaturated fatty acids and for oil, lipid and fatty acid compositions and to their use as drugs, cosmetics, foodstuffs, feedstuffs, preferably fish food, or food supplements.Type: ApplicationFiled: July 30, 2008Publication date: July 29, 2010Applicants: BIORIGINAL FOOD & SCIENCE CORP., BASF PLANT SCIENCE GMBHInventors: Jörg Bauer, Xiao Qiu, Patricia Vrinten
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Publication number: 20100088776Abstract: The present invention relates to polynucleotides from Ostreococcus lucimarinus which code for desaturases and elongases and which can be employed for the recombinant production of polyunsaturated fatty acids. The invention furthermore relates to vectors, host cells and transgenic nonhuman organisms which comprise the polynucleotides, and to the polypeptides encoded by the polynucleotides. Finally, the invention also relates to production processes for the polyunsaturated fatty acids and for oil, lipid and fatty acid compositions.Type: ApplicationFiled: October 4, 2007Publication date: April 8, 2010Applicant: BASF AktiengesellschaftInventors: Jörg Bauer, Tom Wetjen
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Publication number: 20100068761Abstract: The present invention relates to a polynucleotide encoding an omega 3 (?-3) desaturase from Pythium irregulare with specificity to long chain polyunsaturated omega 6 (?-6) fatty acids as well as a vector containing said polynucleotide, and a host cell containing the vector or the polynucleotide. Moreover, the present invention pertains to a polypeptide encoded by the said polynucleotide, antibodies against the polypeptide as well as a method for the manufacture of the polypeptide. Further, encompassed by the present invention are transgenic non-human organisms. Finally, the present invention relates to methods for the manufacture of compounds and oil- fatty acid- or lipid-containing compositions.Type: ApplicationFiled: August 16, 2007Publication date: March 18, 2010Inventors: Jörg Bauer, Guohai Wu, Xiao Qiu
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Publication number: 20100037350Abstract: This invention relates generally to plant cells and/or plants with increased yield as compared to a corresponding non-transformed wild type plant cell by increasing or generating one or more activities of polypeptides associated with the intermediate phosphoribosylpyrophosphate (PRPP) in plants. In particular, this invention relates to plant cells and/or plants with increased yield as compared to a corresponding non-transformed wild type plant cell by increasing or generating one or more activities of phosphoribosyl pyrophosphate synthases (PRPP synthetase, PRS) The invention also deals with methods of producing and screening for and breeding such plant cells and/or plants.Type: ApplicationFiled: October 12, 2007Publication date: February 11, 2010Applicants: BASF Plant Science GmbH, Max-Planck-Institut fuer Molekulare PflanzenphysiologieInventors: Thorsten Zank, Oliver Oswald, Jörg Bauer, Rita Maria Zrenner, Silke Koslowsky