Patents by Inventor Jörg Bentzien

Jörg Bentzien has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tec kinase inhibitors
    Publication number: 20050209284
    Abstract: Disclosed are compounds of formula(I): wherein Ar1, Ar2, R1, R2, R3, R4 and Xa are defined herein. The compounds of the invention inhibit Itk kinase and are therefore useful for treating diseases and pathological conditions involving inflammation, immunological disorders and allergic disorders. Also disclosed are processes for preparing these compounds and to pharmaceutical compositions comprising these compounds.
    Type: Application
    Filed: February 9, 2005
    Publication date: September 22, 2005
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Joerg Bentzien, Brian Cook, Xiang Li, Ho Lo, Chuk Man, Ingo Mugge, Peter Nemoto, Steven Pullen, Doris Riether, Gregory Roth, Fariba Soleymanzadeh, Hidenori Takahashi, Ji Wang, Andre White, Renee Zindell
  • Substituted benzimidazole compounds
    Publication number: 20050203158
    Abstract: Disclosed are substituted benzimidazole compounds of formula (I): wherein R1, R2, R3, R4 and Xa are defined herein. The compounds of the invention inhibit Itk kinase and are therefore useful for treating diseases and pathological conditions involving inflammation, immunological disorders and allergic disorders. Also disclosed are processes for preparing these compounds and to pharmaceutical compositions comprising these compounds.
    Type: Application
    Filed: August 1, 2003
    Publication date: September 15, 2005
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Joerg Bentzien, Brian Cook, Charles Cywin, Roman Fleck, Ho Lo, Peter Nemoto, Steven Pullen, Gregory Roth, Roger Snow, Hidenori Takahashi, Ji Wang, Kevin Moriarty, Lei Qiao, Michael Winters
  • Protein design automation for protein libraries
    Publication number: 20040043430
    Abstract: The invention relates to the use of protein design automation (PDA) to generate computationally prescreened secondary libraries of proteins, and to methods and compositions utilizing the libraries.
    Type: Application
    Filed: September 18, 2003
    Publication date: March 4, 2004
    Inventors: Bassil I. Dahiyat, Robert J. Hayes, Joerg Bentzien, Klaus M. Fiebig
  • Protein design automation for protein libraries
    Publication number: 20040043429
    Abstract: The invention relates to the use of protein design automation (PDA) to generate computationally prescreened secondary libraries of proteins, and to methods and compositions utilizing the libraries.
    Type: Application
    Filed: September 18, 2003
    Publication date: March 4, 2004
    Inventors: Bassil I. Dahiyat, Robert J. Hayes, Joerg Bentzien, Klaus M. Fiebig
  • Thermostable alkaliphilic xylanase
    Patent number: 6682923
    Abstract: The invention relates to novel xylanase activity (XA) proteins and nucleic acids. The invention further relates to the use of the XA proteins in the process of pulp bleaching.
    Type: Grant
    Filed: May 12, 2000
    Date of Patent: January 27, 2004
    Assignee: Xencor
    Inventors: Jörg Bentzien, Bassil I. Dahiyat
  • Protein design automation for protein libraries
    Publication number: 20030130827
    Abstract: The invention relates to the use of protein design automation (PDA™) to generate computationally prescreened secondary libraries of proteins, and to methods and compositions utilizing the libraries.
    Type: Application
    Filed: August 12, 2002
    Publication date: July 10, 2003
    Inventors: Joerg Bentzien, Bassil I. Dahiyat, John R. Desjarlais, Robert J. Hayes, Jost Vielmetter
  • Recombinant interferon-beta muteins
    Patent number: 6514729
    Abstract: The invention relates to novel interferon-beta activity (IbA) proteins and nucleic acids. The invention further relates to the use of the IbA proteins in the treatment of IFN-&bgr; related disorders.
    Type: Grant
    Filed: May 11, 2000
    Date of Patent: February 4, 2003
    Assignee: Xencor, Inc.
    Inventor: Jörg Bentzien
  • Protein design automation for protein libraries
    Publication number: 20020090648
    Abstract: The invention relates to the use of protein design automation (P DA) to generate computationally prescreened secondary libraries of proteins, and to methods and compositions utilizing the libraries.
    Type: Application
    Filed: August 10, 2001
    Publication date: July 11, 2002
    Inventors: Bassil I Dahiyat, Joerg Bentzien, Klaus Fiebig, Robert Hayes
  • Protein design automatic for protein libraries
    Patent number: 6403312
    Abstract: The invention relates to the use of protein design automaton (PDA) to generate computationally prescreened secondary libraries of proteins, and to methods and compositions utilizing the libraries.
    Type: Grant
    Filed: October 15, 1999
    Date of Patent: June 11, 2002
    Assignee: Xencor
    Inventors: Bassil I. Dahiyat, Robert J. Hayes, Jörg Bentzien, Klaus M. Fiebig
  • Protein design automation for protein libraries
    Publication number: 20020048772
    Abstract: The invention relates to the use of protein design automation (PDA) to generate computationally prescreened secondary libraries of proteins, and to methods and compositions utilizing the libraries.
    Type: Application
    Filed: February 12, 2001
    Publication date: April 25, 2002
    Inventors: Bassil I. Dahiyat, Robert J. Hayes, Joerg Bentzien, Klaus M. Fiebig