Patents by Inventor Jörg Hackermüller

Jörg Hackermüller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MULTI-GENE EXPRESSION ASSAY FOR PROSTATE CARCINOMA
    Publication number: 20230265522
    Abstract: Prostate cancer is the most prevalent solid cancer among men in Western Countries. The clinical behavior of localized prostate cancer is highly variable. Hence, there is a high clinical need for precise biomarkers for identification of aggressive disease in addition to established clinical parameters. The present invention relates to a prognostic multi-gene expression score based on transcriptome-wide gene expression analysis providing a method for calculating a score (ProstaTrend score) that allows the prediction of death of disease (DoD) and/or biochemical recurrence (BCR), long-term prognosis and outcome of prostate cancer patients. The present invention is an independent predictor of prognosis and is suitable for the identification of high-risk patients among patients with a clinical classification of low or intermediate risk prior and after surgery, such as radical prostatectomy.
    Type: Application
    Filed: April 19, 2021
    Publication date: August 24, 2023
    Inventors: Kristin Reiche, Conny Blumert, Friedemann Horn, Markus Kreuz, Dominik Otto, Catharina Bertram, Jörg Hackermüller, Manfred Wirth, Suzanne Füssel, Michael Fröhner
  • RNA-biomarkers for diagnosis of prostate cancer
    Patent number: 10301683
    Abstract: The invention relates to the identification and selection of differentially expressed transcripts (biomarker) in tumor cells. Specific determination of the level of these biomarkers can be used for screening and diagnosis of prostate cancer. Clinical application of assays based on these biomarker help reduce the high number of false positives of current standard screening assays.
    Type: Grant
    Filed: December 1, 2014
    Date of Patent: May 28, 2019
    Assignee: FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
    Inventors: Friedemann Horn, Jörg Hackermüller, Sabina Christ, Kristin Reiche, Manfred Wirth, Michael Fröhner, Susanne Füssel
  • RNA-biomarkers for diagnosing prostate cancer
    Patent number: 10287634
    Abstract: The invention relates to the identification and selection of differentially expressed transcripts (biomarker) in tumor cells. Specific determination of the level of these biomarkers can be used for screening and diagnosis of prostate cancer. Clinical application of assays based on these biomarker help reduce the high number of false positives of current standard screening assays.
    Type: Grant
    Filed: December 1, 2014
    Date of Patent: May 14, 2019
    Assignee: FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWAND
    Inventors: Friedemann Horn, Jörg Hackermüller, Sabina Christ, Kristin Reiche, Manfred Wirth, Michael Fröhner, Susanne Füssel
  • RNA-biomarkers for diagnosis of prostate cancer
    Patent number: 10196696
    Abstract: The invention relates to the identification and selection of differentially expressed transcripts (biomarker) in tumour cells. Specific determination of the level of these biomarkers can be used for screening and diagnosis of prostate cancer. Clinical application of assays based on these biomarker help reduce the high number of false positives of current standard screening assays.
    Type: Grant
    Filed: December 1, 2014
    Date of Patent: February 5, 2019
    Assignee: FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWAND
    Inventors: Friedemann Horn, Jörg Hackermüller, Sabina Christ, Kristin Reiche, Manfred Wirth, Michael Fröhner, Susanne Füssel
  • RNA-biomarkers for diagnosis of prostate cancer
    Patent number: 10196695
    Abstract: The invention relates to the identification and selection of differentially expressed transcripts (biomarker) in tumour cells. Specific determination of the level of these biomarkers can be used for screening and diagnosis of prostate cancer. Clinical application of assays based on these biomarker help reduce the high number of false positives of current standard screening assays.
    Type: Grant
    Filed: December 1, 2014
    Date of Patent: February 5, 2019
    Assignee: FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG
    Inventors: Friedemann Horn, Jörg Hackermüller, Sabina Christ, Kristin Reiche, Manfred Wirth, Michael Fröhner, Susanne Füssel
  • NOVEL RNA-BIOMARKER SIGNATURE FOR DIAGNOSIS OF PROSTATE CANCER
    Publication number: 20170362662
    Abstract: The invention relates to the identification and selection of differentially expressed transcripts (biomarker) in tumour cells. Specific determination of the level of these biomarkers can be used for screening and diagnosis of prostate cancer. Clinical application of assays based on these biomarker help reduce the high number of false positives of current standard screening assays.
    Type: Application
    Filed: December 1, 2015
    Publication date: December 21, 2017
    Applicant: FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
    Inventors: Friedemann Horn, Jörg Hackermüller, Sabina Christ, Kristin Reiche, Manfred Wirth, Michael Fröhner, Susanne Füssel
  • NOVEL RNA-BIOMARKERS FOR DIAGNOSIS OF PROSTATE CANCER
    Publication number: 20160312291
    Abstract: The invention relates to the identification and selection of differentially expressed transcripts (biomarker) in tumour cells. Specific determination of the level of these biomarkers can be used for screening and diagnosis of prostate cancer. Clinical application of assays based on these biomarker help reduce the high number of false positives of current standard screening assays.
    Type: Application
    Filed: December 1, 2014
    Publication date: October 27, 2016
    Inventors: Friedemann Horn, Jörg Hackermüller, Sabina Christ, Kristin Reiche, Manfred Wirth, Michael Fröhner, Susanne Füssel
  • NOVEL RNA-BIOMARKERS FOR DIAGNOSIS OF PROSTATE CANCER
    Publication number: 20160304967
    Abstract: The invention relates to the identification and selection of differentially expressed transcripts (biomarker) in tumour cells. Specific determination of the level of these biomarkers can be used for screening and diagnosis of prostate cancer. Clinical application of assays based on these biomarker help reduce the high number of false positives of current standard screening assays.
    Type: Application
    Filed: December 1, 2014
    Publication date: October 20, 2016
    Inventors: Friedemann Horn, Jörg Hackermüller, Sabina Christ, Kristin Reiche, Manfred Wirth, Michael Fröhner, Susanne Füssel
  • NOVEL RNA-BIOMARKERS FOR DIAGNOSIS OF PROSTATE CANCER
    Publication number: 20160304965
    Abstract: The invention relates to the identification and selection of differentially expressed transcripts (biomarker) in tumour cells. Specific determination of the level of these biomarkers can be used for screening and diagnosis of prostate cancer. Clinical application of assays based on these biomarker help reduce the high number of false positives of current standard screening assays.
    Type: Application
    Filed: December 1, 2014
    Publication date: October 20, 2016
    Inventors: Friedemann Horn, Jörg Hackermüller, Sabina Christ, Kristin Reiche, Manfred Wirth, Michael Fröhner, Susanne Füssel
  • NOVEL RNA-BIOMARKERS FOR DIAGNOSING PROSTATE CANCER
    Publication number: 20160304966
    Abstract: The invention relates to the identification and selection of differentially expressed transcripts (biomarker) in tumour cells. Specific determination of the level of these biomarkers can be used for screening and diagnosis of prostate cancer. Clinical application of assays based on these biomarker help reduce the high number of false positives of current standard screening assays.
    Type: Application
    Filed: December 1, 2014
    Publication date: October 20, 2016
    Inventors: Friedemann Horn, Jörg Hackermüller, Sabina Christ, Kristin Reiche, Manfred Wirth, Michael Fröhner, Susanne Füssel
  • NOVEL RNA-BIOMARKERS FOR DIAGNOSIS OF PROSTATE CANCER
    Publication number: 20160298199
    Abstract: The invention relates to the identification and selection of differentially expressed transcripts (biomarker) in tumour cells. Specific determination of the level of these biomarkers can be used for screening and diagnosis of prostate cancer. Clinical application of assays based on these biomarker help reduce the high number of false positives of current standard screening assays.
    Type: Application
    Filed: December 1, 2014
    Publication date: October 13, 2016
    Inventors: Friedemann Horn, Jörg Hackermüller, Sabina Christ, Kristin Reiche, Manfred Wirth, Michael Fröhner, Susanne Füssel
  • miRNA compounds for treatment of prostate carcinoma
    Patent number: 8980854
    Abstract: The invention inter alia relates to new pharmaceutical compositions comprising miRNAs miR-130a, miR-203 and miR-205, and their use for the treatment of cancer, in particular prostate cancer.
    Type: Grant
    Filed: August 12, 2010
    Date of Patent: March 17, 2015
    Assignee: Fraunhofer-Gesellschaft zur Forderung der Angewandten Forschung E.V.
    Inventors: Kerstin Boll, Friedemann Horn, Jörg Hackermüller
  • miRNA Compounds for Treatment of Prostate Carcinoma
    Publication number: 20130018087
    Abstract: The invention inter alia relates to new pharmaceutical compositions comprising miRNAs mi R-130a, mi R-203 and miR-205, and their use for the treatment of cancer, in particular prostate cancer.
    Type: Application
    Filed: August 12, 2010
    Publication date: January 17, 2013
    Applicant: Fraunhofer-Gesellschaft Zur Forderung Der Angewandten Forschung E.V.
    Inventors: Kerstin Boll, Friedemann Horn, Jörg Hackermüller