Patents by Inventor Jörg Kauling
Jörg Kauling has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210071131Abstract: What is described herein relates to a prechamber for an inclined channel gravity cell separator with a multitude of channels for retaining cells from a reactor mixture, wherein said prechamber comprises at least one inlet for flow distribution of an incoming fluid stream and at least one aperture towards the multitude of channels and wherein said prechamber encloses a 3-dimensional space.Type: ApplicationFiled: April 17, 2019Publication date: March 11, 2021Inventors: Marc JENNE, Helmut BROD, Joerg KAULING, Helge MOEBUS
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Patent number: 9840691Abstract: The invention relates to the use of single- or multilayer plastic web plates in a sloped channel-type solid material separator with a lamella package.Type: GrantFiled: February 20, 2013Date of Patent: December 12, 2017Assignee: BAYER AKTIENGESELLSCHAFTInventors: Andre Pastor, Juri Seletzky, Helmut Brod, Joerg Kauling, Peter Commer
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Patent number: 9809792Abstract: The invention relates to a separator for retaining and recirculating cells in a continuous-flow or batch-flow type plastic bag or bottle, which can preferably be operated outside of a bioreactor. Additionally, the invention relates to a method for retaining and recirculating cells within or outside a bioreactor. The invention further relates to a method for producing the separator according to the invention.Type: GrantFiled: February 20, 2013Date of Patent: November 7, 2017Assignee: BAYER AKTIENGESELLSCHAFTInventors: Joerg Kauling, Juri Seletzky, Jorgen Magnus, Andre Pastor, Helmut Brod
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Patent number: 9199347Abstract: Device for mounting flexible, profiled hollow cylinders onto cylindrical elements. Profiled hollow cylinders which are mounted onto a cylindrical element form excellent modules for irradiating fluid media with electromagnetic radiation.Type: GrantFiled: July 22, 2014Date of Patent: December 1, 2015Assignee: Bayer Intellectual Property GmbHInventors: Martin Poggel, Jörg Kauling, Sebastian Schmidt, Erhard Beckers
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Publication number: 20150218501Abstract: The invention relates to a reactor tank designed as a disposable element having a cover and/or sensor patches readable opto-electronically fixed in the interior, a reactor comprising the reactor tank and reactor tank receiving peripherals, the same comprising a reactor tank holder and optionally an opto-electronic measuring system for reading sensor patches, wherein the reactor tank holder is coupled to a drive unit for generating a rotating-oscillation motion of the reactor tank around the central vertical axis thereof, and also the use of this device for culturing cells and/or microorganisms.Type: ApplicationFiled: September 13, 2013Publication date: August 6, 2015Applicant: BAYER TECHNOLOGY SERVICES GMBHInventors: Joerg Kauling, Annette Waldhelm, Helmut Brod, Verena Herrmann, Stefanie Jacob
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Publication number: 20150024478Abstract: The invention relates to the use of single- or multilayer plastic web plates in a sloped channel-type solid material separator with a lamella package.Type: ApplicationFiled: February 20, 2013Publication date: January 22, 2015Applicants: BAYER TECHNOLOGY SERVICES GMBh, MAYER INTELLECTUAL PROPERTY GMBHInventors: Andre Pastor, Juri Seletzky, Helmut Brod, Joerg Kauling, Peter Commer
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Publication number: 20150017716Abstract: The invention relates to a separator for retaining and recirculating cells in a continuous-flow or batch-flow type plastic bag or bottle, which can preferably be operated outside of a bioreactor. Additionally, the invention relates to a method for retaining and recirculating cells within or outside a bioreactor. The invention further relates to a method for producing the separator according to the invention.Type: ApplicationFiled: February 20, 2013Publication date: January 15, 2015Inventors: Joerg Kauling, Juri Seletzky, Jorgen Magnus, Andre Pastor, Helmut Brod
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Publication number: 20140373328Abstract: Device for mounting flexible, profiled hollow cylinders onto cylindrical elements. Profiled hollow cylinders which are mounted onto a cylindrical element form excellent modules for irradiating fluid media with electromagnetic radiation.Type: ApplicationFiled: July 22, 2014Publication date: December 25, 2014Inventors: Martin POGGEL, Jörg KAULING, Sebastian SCHMIDT, Erhard BECKERS
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Publication number: 20140317951Abstract: The invention relates to a device for filtration, drying and storage of solids from a suspension (FDS unit) and a method carried out in this system for the downstream processing of a solids suspension, in particular of crystallizable therapeutic proteins or active ingredients. The FDS unit, designed for use as a disposable system, is a device with which active ingredient crystals can be gently and safely filtered, dried, stored and reconstituted in a closed process procedure, i.e. without intermediate opening or transfer.Type: ApplicationFiled: November 14, 2012Publication date: October 30, 2014Applicant: BAYER INTELLECTUAL PROPERTY GMBHInventors: Joerg Kauling, Andre Pütz, Dirk Havekost, Jörg Peters
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Patent number: 8869371Abstract: Profiled hollow cylinders attached to a cylinder-shaped body as modules for radiating fluid media with electromagnetic radiation.Type: GrantFiled: February 3, 2010Date of Patent: October 28, 2014Assignee: Bayer Intellectual Property GmbHInventors: Martin Poggel, Joerg Kauling, Sebastian Schmidt, Erhard Beckers
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Publication number: 20140293734Abstract: The invention relates to a reactor driven in an oscillatory-rotary manner about its fixed, preferably vertical, axis, for preferably biotechnological and pharmaceutical applications. By means of its process-intensifying properties for mixing, suspension, gaseous material transport, heat transfer, irradiation and particle retention, the applicability on the industrial scale is ensured. The reactor which succeeds without a shaft seal permits particularly robust production with respect to sterile technique with avoidance of cleaning and cleaning validation required when the reactor is constructed as a single-use reactor.Type: ApplicationFiled: May 15, 2014Publication date: October 2, 2014Inventors: Jörg KAULING, Helmut BROD, Sebastian SCHMIDT, Martin POGGEL, Björn FRAHM, Reinhold ROSE
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Publication number: 20140080213Abstract: The invention relates to a reactor driven in an oscillatory-rotary manner about its fixed, preferably vertical, axis, for preferably biotechnological and pharmaceutical applications. By means of its process-intensifying properties for mixing, suspension, gaseous material transport, heat transfer, irradiation and particle retention, the applicability on the industrial scale is ensured. The reactor which succeeds without a shaft seal permits particularly robust production with respect to sterile technique with avoidance of cleaning and cleaning validation required when the reactor is constructed as a single-use reactor.Type: ApplicationFiled: October 7, 2013Publication date: March 20, 2014Inventors: Jörg KAULING, Helmut BROD, Sebastian SCHMIDT, Martin POGGEL, Björn FRAHM, Reinhold ROSE
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Patent number: 8647592Abstract: Method for transport of suspensions containing mechanically sensitive material with a sample-transporting device comprising transport conduits and at least one system for accelerating a sample or aliquot through the transport conduit from at least two burets.Type: GrantFiled: March 21, 2013Date of Patent: February 11, 2014Assignee: Bayer Technology Services GmbHInventors: Stefan Steigmiller, Hans Tups, Karsten Sommer, Sonja Danstedt, Martin Schiffhauer, Sebastian Schmidt, Jörg Kauling, Arndt Braun
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Patent number: 8602636Abstract: The invention relates to a reactor driven in an oscillatory-rotary manner about its fixed, preferably vertical, axis, for preferably biotechnological and pharmaceutical applications. By means of its process-intensifying properties for mixing, suspension, gaseous material transport, heat transfer, irradiation and particle retention, the applicability on the industrial scale is ensured. The reactor which succeeds without a shaft seal permits particularly robust production with respect to sterile technique with avoidance of cleaning and cleaning validation required when the reactor is constructed as a single-use reactor.Type: GrantFiled: April 23, 2007Date of Patent: December 10, 2013Assignee: Bayer Intellectual Property GmbHInventors: Jörg Kauling, Helmut Brod, Sebastian Schmidt, Martin Poggel, Björn Frahm, Reinhold Rose
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Patent number: 8431089Abstract: Sampling valve with which samples containing mechanically sensitive material are removed in a sterile manner from a bioreactor, and process analysis system with analysis stations, in particular chromatography systems, biosensors and cell determination devices, permitting automated, sterile removal of a sample from a bioreactor and gentle transport of the sample, containing mechanically sensitive material, in particular cells, to the analysis station.Type: GrantFiled: April 17, 2007Date of Patent: April 30, 2013Assignee: Bayer Technology Services GmbHInventors: Stefan Steigmiller, Hans Tups, Karsten Sommer, Sonja Danstedt, Martin Schiffhauer, Sebastian Schmidt, Jörg Kauling, Arndt Braun
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Patent number: 8328167Abstract: The present invention relates to a device for the aeration of liquid media by tube aeration, special tube modules contained therein and the use of a device for the aeration of liquid media.Type: GrantFiled: October 25, 2006Date of Patent: December 11, 2012Assignee: Bayer Technology Services GmbHInventors: Jörg Kauling, Hans-Jürgen Henzler, Sebastian Schmidt, Helmut Brod, Klaus Kaiser, Stephan Kirchner, Dirk Havekost
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Publication number: 20120234394Abstract: The invention relates to a sparger for introducing a gas or gas mixture into a liquid and to a method for sparging liquids. The sparger according to the invention comprises a cavity, a gas inlet for routing a gas into the cavity and two or more faces, which are or can be pressed onto one another in a positive fashion such that a gas pressed into the cavity through the gas inlet escapes through the gaps occurring between the pressed together faces.Type: ApplicationFiled: September 4, 2010Publication date: September 20, 2012Applicant: BAYER TECHNOLOGY SERVICES GMBHInventors: Jurl Seletzky, Joerg Kauling, Björn Frahm, Helmut Brod, Marc Jenne, Franz Schmitt
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Patent number: 8232369Abstract: The present invention relates to a method for precipitation of peptide where the mixing step of the peptide with the precipitation aid and the precipitation itself are specially separated.Type: GrantFiled: November 27, 2007Date of Patent: July 31, 2012Assignees: Talecris Biotherapeutics, Inc., Bayer Technology Services GmbHInventors: Hans-Jürgen Henzler, Stephan Kirchner, Dirk Havekost, Klaus Kaiser, Jörg Kauling, Richard Pasquinelli, Rolf Treckmann
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Publication number: 20120100605Abstract: A reactor is designed as a disposable element, a container receives the reactor, and a device comprises a reactor. A drive unit of the device generates a rotating-oscillating motion of the reactor, and the device is utilized for cultivating cells and/or microorganisms.Type: ApplicationFiled: December 3, 2009Publication date: April 26, 2012Applicants: SARTORIUS STEDIM BIOTECH GMBH, BAYER TECHNOLOGY SERVICES GMBHInventors: Joerg Kauling, Bernd Meuser, Arndt Braun, Sebastien Chaussin, Wilfgang Kahlert
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Publication number: 20120052578Abstract: A gas-introduction system useful, for example, in biotechnology for supplying cells or microorganisms with oxygen. The gas-introduction system has a bubble column and a distributor. In the vessel there is situated a liquid medium which is to be supplied with gas. A vector is used as transport medium for the gas. The gas is introduced into the bubble column and here taken up by the vector. The vector is applied to the liquid surface via the distributor in droplet form, falls downward in the medium and releases to the medium some of the gas that has been taken up. At the bottom of the vessel is situated a collecting device in which the vector droplets coalesce and pass back into the bubble column. Disclosed are a bioreactor comprising the gas-introduction system and a method for introducing gas into a liquid medium, preferably an aqueous suspension containing cells or microorganisms.Type: ApplicationFiled: January 13, 2010Publication date: March 1, 2012Applicant: BAYER TECHNOLOGY SERVICES GMBHInventors: Joerg Kauling, Björn Frahm, Andre Pütz, Markus Schindler