Patents by Inventor JÖRG VON HAGEN

JÖRG VON HAGEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR IMPROVING THE SOLUBILITY OF CELL CULTURE MEDIA
    Publication number: 20170321186
    Abstract: The invention relates to a process for improving the solubility of dry cell culture media. Some dry powder cell culture media show poor dissolving properties and result in turbid solutions when they are dissolved in aqueous solutions. Using a stepwise procedure in which the amino acids present in the non-dissolving part are identified and added to a new batch in other particle sizes significantly reduces that problem.
    Type: Application
    Filed: November 13, 2015
    Publication date: November 9, 2017
    Applicant: Merck Patent GmbH
    Inventor: Joerg VON HAGEN
  • CELL CULTURE MEDIA
    Publication number: 20160145565
    Abstract: The present invention relates to cell culture media comprising polymer embedded components. Some components show poor stability in dry powder cell culture media. Others are hygroscopic.
    Type: Application
    Filed: June 16, 2014
    Publication date: May 26, 2016
    Applicant: MERCK PATENT GMBH
    Inventors: Michael Howard RAYNER-BRANDES, Joerg VON HAGEN
  • CELL CULTURE MEDIA
    Publication number: 20150337258
    Abstract: The present invention relates to cell culture media comprising inorganic ester derivatives of tyrosine and/or cysteine. The poor solubility of tyrosine and the often non-sufficient stability of cysteine in cell culture media is overcome by substituting them with an inorganic ester derivative, e.g. with a phosphorylated derivative.
    Type: Application
    Filed: November 14, 2013
    Publication date: November 26, 2015
    Applicant: Merck Patent GmbH
    Inventors: Joerg VON HAGEN, Marcel Andre BREUNING, Christian JASPER
  • PROCESS FOR PRODUCING CELL CULTURE MEDIA
    Publication number: 20150166949
    Abstract: The present invention relates to an a process for manufacturing dry powder cell culture media. The preparation and usage of mixed particles generated by co-lyophilisation leads to homogenously blended cell culture media.
    Type: Application
    Filed: May 17, 2013
    Publication date: June 18, 2015
    Applicant: Merck Patent GmbH
    Inventor: Joerg Von Hagen
  • Process and apparatus for producing cell culture media
    Patent number: 8944352
    Abstract: The present invention relates to an apparatus and a process for manufacturing cell culture media. A specific cooling in combination with a certain type of mill lead to a production process that reduces decrease in the performance of the culture media. Preferably, the process is run continuously.
    Type: Grant
    Filed: November 3, 2011
    Date of Patent: February 3, 2015
    Assignee: Merck Patent GmbH
    Inventors: Jochen Bausch, Joerg von Hagen, Tanino Scaramuzza
  • PROCESS AND APPARATUS FOR PRODUCING CELL CULTURE MEDIA
    Publication number: 20130112786
    Abstract: The present invention relates to an apparatus and a process for manufacturing cell culture media. A specific cooling in combination with a certain type of mill lead to a production process that reduces decrease in the performance of the culture media. Preferably, the process is run continuously.
    Type: Application
    Filed: November 3, 2011
    Publication date: May 9, 2013
    Applicant: MERCK PATENT GmbH
    Inventors: Jochen Bausch, Joerg von Hagen, Tanino Scaramuzza
  • Use of ionic liquids for membrane protein extraction
    Patent number: 8143381
    Abstract: The present invention relates to the use of ionic liquids or of mixtures comprising at least one ionic liquid and at least one further solvent for the extraction of membrane proteins from biological samples, to methods for the extraction of membrane proteins, to a kit for the extraction of these proteins and to the use thereof.
    Type: Grant
    Filed: October 18, 2007
    Date of Patent: March 27, 2012
    Assignee: Merck Patent GmbH
    Inventors: Joerg Von Hagen, Uwe Michelsen, Maria Wehsling
  • Method for the enrichment of phosphorylated and/or glycosylated analytes
    Publication number: 20110070663
    Abstract: The present invention relates to a method for the purification and isolation of phosphorylated and glycosylated analytes using titanium dioxide particles.
    Type: Application
    Filed: April 30, 2009
    Publication date: March 24, 2011
    Inventors: Joerg Von Hagen, Uwe Michelsen
  • METHOD AND AGENT FOR REFOLDING PROTEINS
    Publication number: 20100292447
    Abstract: This invention relates to the use of ionic liquids comprising a cation with at least one electron donor region and one positively charged electrostatic region which are spatially distinct from each other for protein refolding and a method for refolding proteins using said ionic liquids.
    Type: Application
    Filed: September 19, 2008
    Publication date: November 18, 2010
    Applicant: MERCK PATENT GESELLSCHAFT
    Inventors: William-Robert Pitner, Jens Eichhorn, Joerg Von Hagen, Peter A. Leland, Graham B.I. Scott
  • METHOD FOR THE EXTRACTION OF MEMBRANE PROTEINS
    Publication number: 20100273993
    Abstract: The present invention relates to the use of linear, amphipathic carbohydrate polymers for the extraction of membrane proteins from biological samples, to a method for the extraction of membrane proteins, to a kit for the extraction of these proteins, and to the use thereof.
    Type: Application
    Filed: November 17, 2008
    Publication date: October 28, 2010
    Inventors: Joerg Von Hagen, Uwe Michelsen
  • USE OF IONIC LIQUIDS FOR MEMBRANE PROTEIN EXTRACTION
    Publication number: 20100029917
    Abstract: The present invention relates to the use of ionic liquids or of mixtures comprising at least one ionic liquid and at least one further solvent for the extraction of membrane proteins from biological samples, to methods for the extraction of membrane proteins, to a kit for the extraction of these proteins and to the use thereof.
    Type: Application
    Filed: October 18, 2007
    Publication date: February 4, 2010
    Applicant: MERCK PATENT GMBH
    Inventors: Joerg Von Hagen, Uwe Michelsen, Maria Wehsling