Abstract: The present application provides methods of treating a disease selected from cutaneous lupus erythematosus (CLE) and Lichen planus (LP) in a patient in need thereof, comprising administering to the patient a therapeutically effective amount of a JAK1 selective inhibitor, or a pharmaceutically acceptable salt thereof.

Abstract: A fluid flow meter serves to determine the flow of a fluid, in particular in the form of gas, in a pipe, wherein the fluid flow meter is configured to generate a first measurement variable and at least a second measurement variable for the fluid and at least a first diagnostic parameter. The fluid flow meter comprises a diagnostic system that is configured to determine a first threshold value for the at least one first diagnostic parameter both based on the first measurement variable and based on the at least one second measurement variable and to output a first message to a higher-ranking control device when said first threshold value is reached.

Abstract: The present application provides methods of treating a disease selected from cutaneous lupus erythematosus (CLE) and Lichen planus (LP) in a patient in need thereof, comprising administering to the patient a therapeutically effective amount of a JAK1 selective inhibitor, or a pharmaceutically acceptable salt thereof.

Abstract: This disclosure relates to ruxolitinib, or a pharmaceutically acceptable salt thereof, and its use in treating prurigo nodularis.

Abstract: The invention relates to a method for producing a cable, comprising both a molding tool with a cavity and with at least one first opening, and a line, said line consisting of at least one wire and a sheath surrounding the at least one wire. According to the invention, the line is inserted into the cavity and is guided out of the cavity via at least the first opening. A molding compound is injected into the cavity of the molding tool in a pressurized manner, wherein the line is pressed onto a seal surface of the cavity by means of the pressure of the molding compound, and the line closes the cavity at the seal surface.

Abstract: An automatic measuring machine for automated determination of a respective density of a plurality of solid-state test pieces that includes a measuring arrangement with a dry weighing device and a wet weighing device. The measuring machine further includes a test piece magazine for holding the plurality of solid-state test pieces, and a feeding unit for feeding the solid-state test pieces from the test piece magazine to the measuring arrangement. The automatic measuring machine sequentially feeds the solid-state test pieces to the measuring arrangement by means of the feeding unit, to weigh the solid-state test pieces using the dry weighing device and the wet weighing device in order to obtain respective weighing measurement values for each solid-state test piece, and to determine a respective density value for each solid-state test piece on the basis of the respective weighing measurement values.

Abstract: This disclosure relates to ruxolitinib, or a pharmaceutically acceptable salt thereof, and its use in treating prurigo nodularis.

Abstract: The invention relates to a method for producing a cable, comprising both a molding tool with a cavity and with at least one first opening, and a line, said line consisting of at least one wire and a sheath surrounding the at least one wire. According to the invention, the line is inserted into the cavity and is guided out of the cavity via at least the first opening. A molding compound is injected into the cavity of the molding tool in a pressurized manner, wherein the line is pressed onto a seal surface of the cavity by means of the pressure of the molding compound, and the line closes the cavity at the seal surface.

Abstract: The present application provides methods of treating a disease selected from cutaneous lupus erythematosus (CLE) and Lichen planus (LP) in a patient in need thereof, comprising administering to the patient a therapeutically effective amount of a JAK1 selective inhibitor, or a pharmaceutically acceptable salt thereof.

Abstract: In a circuit arrangement for reproducing audio information signals recorded in one or a plurality of audio channels on a movable sound carrier, the sound carrier being moved at a normal reproduction speed during reproduction, the arrangement including a noise reduction circuit, each audio channel of the arrangement including an RC network (10, 30) with at least one RC filter, there is provided a gap detection circuit integrated in the reproduction circuit arrangement. This gap detection circuit jointly uses parts of the noise reduction circuit, at least one or a plurality of RC filters of the RC network(s) (10, 30) of the noise reduction circuit, during the time intervals in which gaps in the audio information signals are to be detected by the pause detection circuit when the sound carrier is moved at a higher speed than the normal reproduction speed.

Abstract: A lifting and depositing device for portable containers comprising a plurality of rack and pinion jacks, some of which are mounted on support legs of the container. Each rack and pinion jack has an accessory gearing which can be pivoted outwardly or removed, so that when accessory gearing is pivoted outwardly, a support leg can be manually moved axially relative to its guide part, if the container, e.g., is offset on the loading surface of a truck. Thus, the gearing operation and time-consuming crank work required until now for two idle strokes per work cycle is avoided.