Abstract: A hydraulic power trim lift device for a marine propulsion system has at least one lift cylinder, at least one pump and a tank. The lift cylinder has a lift piston chamber and a lift rod chamber separated from the lift piston chamber by a lift cylinder piston. The pump is connected to the lift rod chamber via a first line arrangement and to the lift piston chamber via a second line arrangement. The lift piston chamber is connected to the tank via the second line arrangement when the first line arrangement is pressurized. The second line arrangement has a flow control device acting in the direction of flow to the tank. Furthermore, a marine propulsion system with such a power trim lift device is provided.

Abstract: A circuit arrangement includes a preprocessing circuit configured to obtain context information related to a user location, a learning circuit configured to determine a predicted user movement based on context information related to a user location to obtain a predicted route and to determine predicted radio conditions along the predicted route, and a decision circuit configured to, based on the predicted radio conditions, identify one or more first areas expected to have a first type of radio conditions and one or more second areas expected to have a second type of radio conditions different from the first type of radio conditions and to control radio activity while traveling on the predicted route according to the one or more first areas and the one or more second areas.

Abstract: The invention relates to a method and an apparatus for the plasma treatment of containers. The essential aspect according to the method according to the invention is that, after the plasma treatment at the plasma station and before the container is filled, at least the container interior of the container is at least partially ventilated with a sterilization medium, i.e. is loaded with a sterilization medium.

Abstract: An apparatus for treating containers includes a fixed machine element, a rotating machine element, first and second walls that delimit an interior. The first wall is part of the fixed machine element and the second wall is part of the rotating machine element. A labyrinth seal is formed between the first and second walls, the labyrinth seal has an annular slit that forms a channel. The channel has an inner end that faces the interior and an outer end that faces away from the interior. An underpressure source comprising a blade is at the outer end. Rotation of the underpressure source causes the blade to generate an underpressure in the labyrinth seal. This underpressure generates gas flow from the inner end to the outer end.

Abstract: An apparatus for grouped take-up and feeding of a container-group of containers to a cyclical processing machine having a cyclical take-up device for taking up the group of containers includes an intake, a feed, and a transfer apparatus arranged in a transfer region between the intake and the take-up device. The intake forms a closed conveyor section that comprises a linear section, a conveyor, and carrying-and-holding elements that convey containers in a continuous container stream along the conveyor section. The feed uses mechanical propulsion to convey suspended containers to individually transfer the suspended containers to the carrying-and-holding elements. The transfer apparatus has rotatable grippers for taking up a container group from the container stream and after having taken up the group of containers, feeding the group of containers to the cyclical take-up device.

Abstract: An apparatus for grouped take-up and feeding of a container-group of containers to a cyclical processing machine having a cyclical take-up device for taking up the group of containers includes an intake, a feed, and a transfer apparatus arranged in a transfer region between the intake and the take-up device. The intake forms a closed conveyor section that comprises a linear section, a conveyor, and carrying-and-holding elements that convey containers in a continuous container stream along the conveyor section. The feed uses mechanical propulsion to convey suspended containers to individually transfer the suspended containers to the carrying-and-holding elements. The transfer apparatus has rotatable grippers for taking up a container group from the container stream and after having taken up the group of containers, feeding the group of containers to the cyclical take-up device.

Abstract: The invention relates to a method and an apparatus for the plasma treatment of containers. The essential aspect according to the method according to the invention is that, after the plasma treatment at the plasma station and before the container is filled, at least the container interior of the container is at least partially ventilated with a sterilization medium, i.e. is loaded with a sterilization medium.

Abstract: A filling system includes filling elements, each of which has a channel formed in its housing. During filling, filling material, under a liquid valve's control, passes through the channel and exits through an opening and into a container held on a vertically displaceable container carrier. During pressure filling, the container carrier seals the container against the filling element. During cleaning and sterilization, rinsing caps seal each opening. Each filling element is associated with an extension that seals the outlet. Each extension has a filling-material through-passage that, when the extension is sealed against said outlet, extends the filling-material channel.

Abstract: A rotary feed includes a static part that remains stationary relative to a stationary reference frame and a rotating part that rotates with a rotor. The static part and rotating part run adjacent to each other and define a sealed flow channel for a first medium. A buffer chamber surrounds the static and rotating parts, and the transition between these parts. During operation, a barrier medium charges it at a transition between the static and rotating parts. An outlet connects the buffer chamber to a treatment head to permit a medium in the buffer to be fed to the nozzle for container treatment.

Abstract: The present application relates to novel binder drug conjugates (ADCs), to active metabolites of these ADCs, to processes for preparing these ADCs, to the use of these ADCs for the treatment and/or prophylaxis of diseases and to the use of these ADCs for preparing medicaments for treatment and/or prophylaxis of diseases, in particular hyperproliferative and/or angiogenic disorders such as, for example, cancer diseases. Such treatments can be effected as monotherapy or else in combination with other medicaments or further therapeutic measures.

Abstract: A filling system includes filling elements, each of which has a channel formed in its housing. During filling, filling material, under a liquid valve's control, passes through the channel and exits through an opening and into a container held on a vertically displaceable container carrier. During pressure filling, the container carrier seals the container against the filling element. During cleaning and sterilization, rinsing caps seal each opening. Each filling element is associated with an extension that seals the outlet. Each extension has a filling-material through-passage that, when the extension is sealed against said outlet, extends the filling-material channel.

Abstract: The present invention provides recombinant antigen-binding regions and antibodies and functional fragments containing such antigen-binding regions that are specific for the membrane-anchored, 29 kDa C4.4a polypeptide, which is over expressed in several tumors, e.g. lung, colorectal, pancreas, prostate, renal and breast cancer. These antibodies, accordingly, can be used to treat these and other disorders and conditions. Antibodies of the invention also can be used in the diagnostics field, as well as for further investigating the role of C4.4a in the progression of disorders associated with cancer. The invention also provides nucleic acid sequences encoding the foregoing antibodies, vectors containing the same, pharmaceutical compositions and kits with instructions for use.

Abstract: A rotary feed includes a static part that remains stationary relative to a stationary reference frame and a rotating part that rotates with a rotor. The static part and rotating part run adjacent to each other and define a sealed flow channel for a first medium. A buffer chamber surrounds the static and rotating parts, and the transition between these parts. During operation, a barrier medium charges it at a transition between the static and rotating parts. An outlet connects the buffer chamber to a treatment head to permit a medium in the buffer to be fed to the nozzle for container treatment.

Abstract: The present invention provides antibodies, or antigen-binding antibody fragments thereof, or variants thereof which reduce the cell surface expression of FGFR2 after binding to FGFR2 in both cells overexpressing FGFR2 and cells expressing mutated FGFR2. Also provided are antibody-based therapies for FGFR2-related diseases or conditions such as cancer. Antibodies of the invention also can be used in the diagnostics field. The invention also provides nucleic acid sequences encoding the foregoing antibodies, vectors containing the same, pharmaceutical compositions and kits with instructions for use.

Abstract: The present invention provides recombinant antigen-binding regions and antibodies and functional fragments containing such antigen-binding regions that are specific for the membrane-anchored, 29 kDa C4.4a polypeptide, which is over expressed in several tumors, e.g. lung, colorectal, pancreas, prostate, renal and breast cancer. These antibodies, accordingly, can be used to treat these and other disorders and conditions. Antibodies of the invention also can be used in the diagnostics field, as well as for further investigating the role of C4.4a in the progression of disorders associated with cancer. The invention also provides nucleic acid sequences encoding the foregoing antibodies, vectors containing the same, pharmaceutical compositions and kits with instructions for use.

Abstract: The present invention relates to a sun visor for a motor vehicle, with a planar, elongate main visor body which is mounted rotatably on a rotary spindle running approximately perpendicularly to the longitudinal extent of the main visor body, the rotary spindle being coupled to a main swivel spindle for swiveling the main visor body from a not-in-use position into a use position and vice versa, the main swivel spindle, in the not-in-use position, being integrated in the roof (6) of the motor vehicle parallel to the longitudinal extent of the main visor body and at a distance from the same.

Abstract: The present invention relates to chimeras of human tissue factor inhibitor domain 1 with natural and non-natural Kunitz domains, and their preparation and use.

Abstract: The invention relates to an automobile service building with sufficient useful area for all the functions that are required for this purpose. In order to make it possible to offer services with an acceptable investment cost outlay in this building, even close to the center of large cities, without any restriction to the useful area to the scope of the servicin, all the facilities for the various functions are, according to the invention, arranged one above the other on a large number of floors in a standard, tower-like building with a small ground area requirement, with a tower diameter based on approximately four times the length of a passenger vehicle.

Abstract: The present invention relates to novel arylsulphonamides and analogues, to processes for their preparation and to their use for the prophylaxis and treatment of neurodegenerative disorders, in particular for the treatment of cerebral apoplexy, craniocerebral trauma, pain and spasticity.

Abstract: The present invention relates to new aryl ether sulphonamides and analogues, processes for their preparation and their use for the treatment of neurodegenerative disorders, in particular for the prophylaxis and treatment of neurodegenerative disorders, in particular for the treatment of cerebral apoplexy and craniocerebral trauma.