Patents by Inventor Jürgen Patzke

Jürgen Patzke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GLOBAL TEST FOR DETERMINING THE STATUS OF THE BLOOD COAGULATION SYSTEM
    Publication number: 20230280359
    Abstract: Embodiments of the present invention are in the field of blood coagulation diagnostics and relate to a test for establishing an individual's blood coagulation system status based on the amount of in-vitro-generated F1+2 peptide, and to a test kit for use in such a method.
    Type: Application
    Filed: March 2, 2023
    Publication date: September 7, 2023
    Applicant: Siemens Healthcare Diagnostics Products GmbH
    Inventor: Juergen PATZKE
  • Methods and kits for determining von willebrand factor activity in the absence of ristocetin
    Patent number: 10591490
    Abstract: Described herein are method(s), kit(s), reagent(s) and the like for determining von Willebrand factor (VWF) activity in a sample in the absence of ristocetin.
    Type: Grant
    Filed: December 8, 2017
    Date of Patent: March 17, 2020
    Assignee: SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH
    Inventors: Harald Althaus, Tobias Obser, Juergen Patzke, Reinhard Schneppenheim
  • Preparation of lipemic plasma or serum samples for the determination of a lipid interference
    Patent number: 10488308
    Abstract: The present invention is in the field of in vitro diagnostics and relates to a method for preparing lipemic plasma or serum samples and the use thereof for establishing a lipid interference in the quantitative determination of the amount or the activity of an analyte in a plasma or serum sample.
    Type: Grant
    Filed: September 7, 2017
    Date of Patent: November 26, 2019
    Inventor: Juergen Patzke
  • ASSAY KIT AND METHOD FOR DETECTING MODULATORS OF GPIB-THROMBIN INTERACTION
    Publication number: 20190227084
    Abstract: The present invention is in the field of coagulation diagnostics and relates to methods for detecting modulators of GPIb-thrombin interaction in a sample. To this end, the sample is contacted with isolated mutated GPIb? protein and thrombin, and the formation of a complex between mutated GPIb? protein and thrombin is determined.
    Type: Application
    Filed: April 9, 2019
    Publication date: July 25, 2019
    Inventor: Juergen Patzke
  • Method for detecting modulators of GPIb-thrombin interaction
    Patent number: 10281480
    Abstract: The present invention is in the field of coagulation diagnostics and relates to methods for detecting modulators of GPIb-thrombin interaction in a sample. To this end, the sample is contacted with isolated mutated GPIb? protein and thrombin, and the formation of a complex between mutated GPIb? protein and thrombin is determined.
    Type: Grant
    Filed: March 10, 2015
    Date of Patent: May 7, 2019
    Assignee: Siemens Healthcare Diagnostics Products GmbH
    Inventor: Juergen Patzke
  • Methods And Kits For Determining Von Willebrand Factor Activity In The Absence Of Ristocetin
    Publication number: 20180088133
    Abstract: Described herein are method(s), kit(s), reagent(s) and the like for determining von Willebrand factor (VWF) activity in a sample in the absence of ristocetin.
    Type: Application
    Filed: December 8, 2017
    Publication date: March 29, 2018
    Applicant: SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH
    Inventors: Harald Althaus, Tobias Obser, Juergen Patzke, Reinhard Schneppenheim
  • PREPARATION OF LIPEMIC PLASMA OR SERUM SAMPLES FOR THE DETERMINATION OF A LIPID INTERFERENCE
    Publication number: 20180067022
    Abstract: The present invention is in the field of in vitro diagnostics and relates to a method for preparing lipemic plasma or serum samples and the use thereof for establishing a lipid interference in the quantitative determination of the amount or the activity of an analyte in a plasma or serum sample.
    Type: Application
    Filed: September 7, 2017
    Publication date: March 8, 2018
    Inventor: Juergen Patzke
  • Methods and kits for determining von Willebrand factor activity in the absence of ristocetin
    Patent number: 9869683
    Abstract: Described herein are method(s), kit(s), reagent(s) and the like for determining von Willebrand factor (VWF) activity in a sample in the absence of ristocetin.
    Type: Grant
    Filed: December 10, 2015
    Date of Patent: January 16, 2018
    Assignee: SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH
    Inventors: Harald Althaus, Tobias Obser, Juergen Patzke, Reinhard Schneppenheim
  • Screening process for finding samples having a functionality disorder of the GPIb-von willebrand factor interaction
    Patent number: 9766234
    Abstract: The invention relates to a screening process for determining a disordered von Willebrand factor (VWF)-GPIb interaction in a patient's sample. This comprises contacting the sample with isolated GPIb.alpha. protein, with VWF protein and with a solid phase associated with an antibody specific for said isolated GPIb.alpha. protein, and determining complex formation.
    Type: Grant
    Filed: February 28, 2013
    Date of Patent: September 19, 2017
    Assignee: SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH
    Inventor: Juergen Patzke
  • Methods And Kits For Determining Von Willebrand Factor Activity In The Absence Of Ristocetin
    Publication number: 20160231331
    Abstract: Described herein are method(s), kit(s), reagent(s) and the like for determining von Willebrand factor (VWF) activity in a sample in the absence of ristocetin.
    Type: Application
    Filed: December 10, 2015
    Publication date: August 11, 2016
    Applicant: SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH
    Inventors: Harald Althaus, Tobias Obser, Juergen Patzke, Reinhard Schneppenheim
  • Methods and kits for determining von willebrand factor activity in the absence of ristocetin
    Patent number: 9222942
    Abstract: Described herein are method(s), kit(s), reagent(s) and the like for determining von Willebrand factor (VWF) activity in a sample in the absence of ristocetin.
    Type: Grant
    Filed: January 6, 2010
    Date of Patent: December 29, 2015
    Assignee: SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH
    Inventors: Harald Althaus, Tobias Obser, Juergen Patzke, Reinhard Schneppenheim
  • METHOD FOR DETECTING MODULATORS OF GPIB-THROMBIN INTERACTION
    Publication number: 20150260736
    Abstract: The present invention is in the field of coagulation diagnostics and relates to methods for detecting modulators of GPIb-thrombin interaction in a sample. To this end, the sample is contacted with isolated mutated GPIb? protein and thrombin, and the formation of a complex between mutated GPIb? protein and thrombin is determined.
    Type: Application
    Filed: March 10, 2015
    Publication date: September 17, 2015
    Inventor: Juergen Patzke
  • Methods and kits for determining von Willebrand factor activity in the absence of ristocetin and for determining the activity of ADAMTS-13 protease
    Patent number: 8932820
    Abstract: Described herein are method(s), kit(s), reagent(s) and the like for determining von Willebrand factor (VWF) activity in a sample in the absence of ristocetin.
    Type: Grant
    Filed: September 13, 2012
    Date of Patent: January 13, 2015
    Assignee: Siemens Healthcare Diagnostics Products GmbH
    Inventors: Harald Althaus, Tobias Obser, Juergen Patzke, Reinhard Schneppenheim
  • METHOD FOR DETERMINING PROTEIN S ACTIVITY
    Publication number: 20140242621
    Abstract: The invention relates to a method for determining the protein Ca-cofactor activity of protein S, wherein the protein Ca-cofactor activity of protein S is measured in a first reaction volume in the absence of a protein S inhibitor and in a second reaction volume in the presence of a protein S inhibitor. The protein Ca-cofactor activity of protein S is determined by calculating the quotient of the assay result of the first reaction volume and the assay result of the second reaction volume.
    Type: Application
    Filed: February 12, 2014
    Publication date: August 28, 2014
    Applicant: Siemens Healthcare Products Diagnostics GmbH
    Inventors: Juergen Patzke, Joern Meuer, Thomas Wissel
  • METHOD FOR DETERMINING PLATELET-ASSOCIATED ANALYTES
    Publication number: 20140080144
    Abstract: The present invention relates to a routine in vitro method for determining platelet-associated analytes, for example VWF, factor XIII, fibrinogen or D-dimer, in a sample of platelet-rich plasma.
    Type: Application
    Filed: September 18, 2013
    Publication date: March 20, 2014
    Applicant: SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH
    Inventor: Juergen Patzke
  • Screening process for finding samples having a functionality disorder of the GPIb-von Willebrand factor interaction
    Publication number: 20130230868
    Abstract: The invention relates to a screening process for determining a disordered von Willebrand factor (VWF)-GPIb interaction in a patient's sample. This comprises contacting the sample with isolated GPIb? protein, with VWF protein and with a solid phase associated with an antibody specific for said isolated GPIb? protein, and determining complex formation.
    Type: Application
    Filed: February 28, 2013
    Publication date: September 5, 2013
    Applicant: SIEMENS HEALTHCARE DIAGNOSTICS INC.
    Inventor: Juergen Patzke
  • Screening method for finding samples having antiphospholipid antibodies
    Publication number: 20130224777
    Abstract: The present invention is in the field of coagulation diagnostics and relates to a screening process for finding samples containing antiphospholipid antibodies (lupus anticoagulants), wherein the platelet aggregation-stimulating action of said antiphospholipid antibodies is determined in vitro.
    Type: Application
    Filed: February 26, 2013
    Publication date: August 29, 2013
    Applicant: Siemens Healthcare Diagnostics Products GmbH
    Inventor: Juergen Patzke
  • Method for recognizing interferences in in vitro diagnostic assays
    Publication number: 20130224883
    Abstract: The present invention is in the field of in vitro diagnostics and relates to a method for recognizing interfering disruptive factors, such as heterophile antibodies or rheumatoid factors for example, in a sample.
    Type: Application
    Filed: February 26, 2013
    Publication date: August 29, 2013
    Applicant: Siemens Healthcare Diagnostics Products GmbH
    Inventor: Juergen Patzke
  • METHODS AND KITS FOR DETERMINING VON WILLEBRAND FACTOR ACTIVITY IN THE ABSENCE OF RISTOCETIN AND FOR DETERMINING THE ACTIVITY OF ADAMTS-13 PROTEASE
    Publication number: 20130078652
    Abstract: Described herein are method(s), kit(s), reagent(s) and the like for determining von Willebrand factor (VWF) activity in a sample in the absence of ristocetin.
    Type: Application
    Filed: September 13, 2012
    Publication date: March 28, 2013
    Inventors: Harald Althaus, Tobias Obser, Juergen Patzke, Reinhard Schneppenheim
  • Method of assaying von Willebrand factor activity using agglutinatable, fixed platelet fragments
    Patent number: 8178309
    Abstract: The present invention relates to a method for preparing agglutinatable platelet fragments, in which native platelets are treated with ultrasound and a fixative. The platelet fragments are suitable for use in diagnostic assay methods which include an agglutination reaction, such as, for example, in a method for determining VWF activity.
    Type: Grant
    Filed: May 12, 2011
    Date of Patent: May 15, 2012
    Assignee: Siemens Healthcare Diagnostics Products GmbH
    Inventor: Jürgen Patzke