Patents by Inventor Jørgen Scheel-Krüger

Jørgen Scheel-Krüger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for combating adverse effects arising from antipsychotic treatment
    Patent number: 9457018
    Abstract: This invention relates to a method for combating adverse effects arising from antipsychotic treatment. The invention furthermore relates to novel pharmaceutical compositions comprising a therapeutically effective combination of a compound of formula I and an antipsychotic drug.
    Type: Grant
    Filed: September 2, 2009
    Date of Patent: October 4, 2016
    Assignee: Saniona A/S
    Inventors: Jørgen Scheel-Krüger, Henrik Björk Hansen
  • METHOD FOR COMBATING ADVERSE EFFECTS ARISING FROM ANTIPSYCHOTIC TREATMENT
    Publication number: 20120202796
    Abstract: This invention relates to a method for combating adverse effects arising from antipsychotic treatment. The invention furthermore relates to novel pharmaceutical compositions comprising a therapeutically effective combination of a compound of formula I and an antipsychotic drug.
    Type: Application
    Filed: September 2, 2009
    Publication date: August 9, 2012
    Applicant: NEUROSEARCH A/S
    Inventors: Jørgen Scheel-Krüger, Henrik Björk Hansen
  • Substituted aryloxy alkylamines and their use as monoamine neurotransmitter re-uptake inhibitors
    Patent number: 7973082
    Abstract: This invention relates to novel substituted aryloxy alkylamines useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Grant
    Filed: August 24, 2005
    Date of Patent: July 5, 2011
    Assignee: Neurosearch A/S
    Inventors: Birgitte L. Eriksen, Dan Peters, Elsebet Østergaard Nielsen, Jørgen Scheel-Krüger, Gunnar M. Olsen
  • NOVEL QUINOLINYLAMIDE DERIVATIVES USEFUL AS MODULATORS OF DOPAMINE AND SEROTONIN RECEPTORS
    Publication number: 20110085978
    Abstract: This invention provides novel quinolinylamide derivatives having medical utility, in particular as modulators of dopamine and serotonin receptors, preferably the D3, 5HT1A and 5-HT2A receptor subtypes, and in particular useful for the treatment of neuropsychiatric disorders, incl. schizophrenia.
    Type: Application
    Filed: March 13, 2009
    Publication date: April 14, 2011
    Applicant: NeuroSearch A/S
    Inventors: Dan Peters, Lars Christian Rønn, Karin Sandager Nielsen, Jørgen Scheel-Krüger
  • NOVEL ALKYL SUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS
    Publication number: 20110086880
    Abstract: This invention relates to novel alkyl substituted piperidine derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: December 16, 2010
    Publication date: April 14, 2011
    Inventors: Dan PETERS, Gunnar M. Olsen, Elsebet Østergaard Nielsen, Jørgen Scheel-Krüger, Birgitte L. Eriksen
  • Alkyl substituted piperidine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
    Patent number: 7915419
    Abstract: This invention relates to novel alkyl substituted piperidine derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Grant
    Filed: May 7, 2009
    Date of Patent: March 29, 2011
    Assignee: Neurosearch A/S
    Inventors: Dan Peters, Gunnar M. Olsen, Elsebet Østergaard Nielsen, Jørgen Scheel-Krüger, Birgitte L. Eriksen
  • NOVEL ARYL PIPERAZINE DERIVATIVES USEFUL AS MODULATORS OF DOPAMINE AND SEROTONIN RECEPTORS
    Publication number: 20110059019
    Abstract: This invention provides novel aryl piperazine derivatives having medical utility, in particular as modulators of dopamine and serotonin receptors, preferably the D3, 5HT1A and 5-HT2A receptor subtypes, and in particular useful for the treatment of neuropsychiatric disorders, incl. schizophrenia.
    Type: Application
    Filed: January 29, 2009
    Publication date: March 10, 2011
    Applicant: NeuroSearch A/S
    Inventors: Dan Peters, Lars Christian Rønn, Karin Sandager Nielsen, Jørgen Scheel-Krüger
  • 8-aza-bicyclo[3.2.1]octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
    Patent number: 7888358
    Abstract: This invention relates to novel 8-aza-bicyclo[3.2.1]octane derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Grant
    Filed: July 1, 2008
    Date of Patent: February 15, 2011
    Assignee: Neurosearch A/S
    Inventors: Dan Peters, Birgitte L. Eriksen, Elsebet Østergaard Nielsen, Jørgen Scheel-Krüger, Gunnar M. Olsen
  • PHARMACEUTICAL COMPOSITION COMPRISING A MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITOR AND AN ACETYLCHOLINESTERASE INHIBITOR
    Publication number: 20100210626
    Abstract: The invention relates to a pharmaceutical composition comprising a monoamine neurotransmitter re-uptake inhibitor comprising a 2,3-disubstituted tropane moiety, or a tautomer, a pharmaceutically acceptable salt, solvate, or physiologically functional derivative thereof (1), and at least one acetylcholinesterase inhibitor or a pharmaceutically acceptable salt, solvate, or physiologically functional derivative thereof (2), and a pharmaceutically acceptable carrier or excipient, and optionally one or more other therapeutic ingredients.
    Type: Application
    Filed: April 27, 2010
    Publication date: August 19, 2010
    Inventors: Thomas FRIEDL, Joachim MIERAU, Andreas RASCHIG, Juergen REESS, Joergen SCHEEL-KRUEGER
  • 3,8-substituted 8-AZA-bicyclo[3.2.1]octane derivatives and their use as monomine neurotransmitter re-uptake inhibitors
    Patent number: 7713990
    Abstract: This invention relates to novel 8-aza-bicyclo[3.2.1]octane derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Grant
    Filed: January 11, 2006
    Date of Patent: May 11, 2010
    Assignee: NeuroSearch A/S
    Inventors: Dan Peters, Bjarne H. Dahl, Gunnar M. Olsen, Elsebet Østergaard Nielsen, Jørgen Scheel-Krüger, John Paul Redrobe
  • Chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
    Patent number: 7696350
    Abstract: This invention relates to chromen-2-one derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Grant
    Filed: September 28, 2005
    Date of Patent: April 13, 2010
    Assignee: Neurosearch A/S
    Inventors: Dan Peters, Gunnar M. Olsen, Jørgen Scheel-Krüger, Elsebet Østergaard Nielsen
  • ARYL PIPERAZINE DERIVATIVES USEFUL FOR THE TREATMENT OF NEUROPSYCHIATRY DISORDERS
    Publication number: 20100087445
    Abstract: This invention provides novel aryl piperazine derivatives represented by Formula (I) having medical utility, in particular as modulators of dopamine and serotonin receptors, preferably the D3, 5HT1A and 5-HT2A receptor subtypes, and in particular useful for the treatment of neuropsychiatric disorders, incl. schizophrenia.
    Type: Application
    Filed: October 12, 2007
    Publication date: April 8, 2010
    Applicant: Universita degli Studi di Siena
    Inventors: Giuseppe Campiani, Stefania Butini, Caterina Fattorusso, Silvia Franceschini, Irene Zia Thale, Karin Sandager Nielsen, Jørgen Scheel-Krüeger, Lars Siim Madsen
  • Alkyl substituted piperidine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
    Patent number: 7547788
    Abstract: This invention relates to novel alkyl substituted piperidine derivatives useful as monoamine neurotransmitter re-up-take inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Grant
    Filed: June 14, 2005
    Date of Patent: June 16, 2009
    Assignee: NeuroSearch A/S
    Inventors: Dan Peters, Gunnar M. Olsen, Elsebet Østergaard Nielsen, Jørgen Scheel-Krüger, Birgitte L. Eriksen
  • Certain 9-aza-bicyclo[3.3.1] nonane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
    Patent number: 7524958
    Abstract: This invention relates to novel 9-aza-bicyclo[3.3.1]nonane derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Grant
    Filed: June 14, 2005
    Date of Patent: April 28, 2009
    Assignee: Neurosearch A/S
    Inventors: Dan Peters, Gunnar M. Olsen, Elsebet Østergaard Nielsen, Jørgen Scheel-Krüger
  • Triple monoamine reuptake inhibitors for the treatment of chronic pain
    Patent number: 7459464
    Abstract: The present invention relates to the use of triple monoamine reuptake inhibitors for the treatment of chronic pain.
    Type: Grant
    Filed: May 27, 2003
    Date of Patent: December 2, 2008
    Assignee: Neurosearch A/S
    Inventors: Jørgen Scheel-Krüger, Gordon John Blackburn-Munro
  • 8-aza-bicyclo[3.2.1]octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
    Patent number: 7407970
    Abstract: This invention relates to novel 8-aza-bicyclo[3.2.1]octane derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Grant
    Filed: June 18, 2004
    Date of Patent: August 5, 2008
    Assignee: NeuroSearch A/S
    Inventors: Dan Peters, Birgitte L. Eriksen, Elsebet Østergaard Nielsen, Jørgen Scheel-Krüger, Gunnar M. Olsen
  • Tropane derivatives having dopamine reuptake inhibitor activity for the treatment of ischemic diseases
    Patent number: 7381733
    Abstract: The present invention relates to the use of tropane derivatives having dopamine reuptake inhibitor activity for the treatment of diseases associated with reduced blood flow to the brain or with instances of a temporary break in blood supply to the brain, such as ischemic diseases.
    Type: Grant
    Filed: November 28, 2002
    Date of Patent: June 3, 2008
    Assignee: Neurosearch A/S
    Inventors: Jørgen Scheel-Krüger, Lars Christian B. Rønn
  • 8-aza-bicyclo (3.2.1) octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
    Patent number: 7247643
    Abstract: This invention relates to novel 8-aza-bicyclop[3.2.1]octane derivatives useful as monoamine neurotransmitter re-up-take inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Grant
    Filed: February 10, 2004
    Date of Patent: July 24, 2007
    Assignee: NeuroSearch A/S
    Inventors: Dan Peters, Elsebet Østergaard Nielsen, Gunnar M. Olsen, Jørgen Scheel-Krüger
  • Compounds and their use as positive AMPA receptor modulators
    Patent number: 6943159
    Abstract: The invention provides novel compounds represented by general formula (I) wherein the bond represented by the broken line may be a single, double bond or absent; and if the bond is absent, then the nitrogen is substituted with a hydrogen and R2; X represents SO2 or C?O of CH2; Y represents —CH(R4)—, —N(R4)—CH2—, O; and the meaning of R2, R3, R4, R5, R6, R7, and R8 are as defined in the application. The compounds are useful as positive modulators of the AMPA-receptor.
    Type: Grant
    Filed: August 18, 2000
    Date of Patent: September 13, 2005
    Assignee: Neurosearch A/S
    Inventors: Alex Haahr Gouliaev, Mogens Larsen, Thomas Varming, Claus Mathiesen, Tina Holm Johansen, Jørgen Scheel-Krüger, Gunnar M. Olsen, Elsebet Østergaard Nielsen
  • Pharmaceutical composition comprising a monoamine neurotransmitter re-uptake inhibitor and an acetylcholinesterase inhibitor
    Publication number: 20050154009
    Abstract: The invention relates to a pharmaceutical composition comprising a monoamine neurotransmitter re-uptake inhibitor comprising a 2,3-disubstituted tropane moiety, or a tautomer, a pharmaceutically acceptable salt, solvate, or physiologically functional derivative thereof, and at least one acetylcholinesterase inhibitor or a pharmaceutically acceptable salt, solvate, or physiologically functional derivative thereof, and a pharmaceutically acceptable carrier or excipient, and optionally one or more other therapeutic ingredients.
    Type: Application
    Filed: October 15, 2004
    Publication date: July 14, 2005
    Applicants: Boehringer Ingelheim International GmbH, NeuroSearch A/S
    Inventors: Thomas Friedl, Joachim Mierau, Andreas Raschig, Juergen Reess, Joergen Scheel-Krueger