Patents by Inventor Jörn Tongers

Jörn Tongers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL VEGF MIMETIC PEPTIDE-BASED SCAFFOLDS FOR THERAPEUTIC ANGIOGENESIS AND METHODS FOR THEIR USE
    Publication number: 20130101628
    Abstract: Disclosed herein is a completely synthetic cell-free therapy based on peptide amphiphile nanostructures designed to mimic the activity of vascular endothelial growth factor (VEGF), one of the most potent angiogenic signaling proteins. The VEGF-mimetic filaments disclosed herein were found to induce phosphorylation of VEGF receptors and induce pro-angiogenic behavior in endothelial cells, indicated by an enhancement in proliferation, survival and migration in vitro.
    Type: Application
    Filed: April 29, 2012
    Publication date: April 25, 2013
    Applicant: NORTHWESTERN UNIVERSITY
    Inventors: Matthew J. Webber, Jörn Tongers, Douglas W. Losordo, Samuel I. Stupp