Patents by Inventor J. Scott Crowe

J. Scott Crowe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Labeled humanized anti-CD18 antibodies and fragments and kits comprising same
    Patent number: 6689869
    Abstract: A humanized antibody or antibody fragment having all or part of the CDRs as defined and capable of binding to the human CD18 antigen. The antibody and fragment may be labeled and are useful in a variety of applications, such as in therapy in treating leukocyte mediated conditions such as inhibiting ingress of leukocytes into the lung and other organs and treatment of inflammation. Also provided is a kit for detecting the presence of human CD18 antigen comprising an antibody or fragment of the invention, which is optionally labeled.
    Type: Grant
    Filed: August 23, 1999
    Date of Patent: February 10, 2004
    Assignee: Cambridge University Technical Services Limited
    Inventors: Herman Waldmann, Martin J. Sims, J. Scott Crowe
  • HUMANIZED ANTIBODY AGAINST CD18
    Publication number: 20030185818
    Abstract: A humanized antibody having all or part of the CDRs as defined and capable of binding to the human CD-18 antigen. The antibody is of use in therapy in treating leukocyte mediated conditions such as inhibiting ingress of leukocytes into the lung and other organs and treatment of inflammation.
    Type: Application
    Filed: August 23, 1999
    Publication date: October 2, 2003
    Inventors: HERMAN WALDMANN, Martin J. Sims, J. Scott Crowe
  • Method of using humanized antibody against CD18
    Patent number: 5997867
    Abstract: Methods of treating patients suffering from, or at risk of developing, a leukocyte mediated disease comprising the administration of humanized antibodies and fragments thereof that bind human CD18 are disclosed.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: December 7, 1999
    Inventors: Herman Waldmann, Martin J. Sims, J. Scott Crowe