Abstract: The present disclosure relates to a rotary blood pump system. The rotary blood pump system may comprise an inflow conduit, an outflow conduit, a control system, and a power source. The present disclosure further relates to various inflow conduit assemblies comprising a conduit tip comprised of metal or polymer having an undulating opening surface that provides improved blood flow and washing properties while minimizing regions susceptible to stagnation, and optionally a resilient tip-protecting cage structure that reduces the risk of conduit tip suction events and suction-related injury of the wall of adjacent blood vessels or other blood containing structures. The present disclosure further relates to various outflow conduit assemblies with a conduit tip comprised of metal or polymer wherein the cross-sectional area of the lumen of the conduit or conduit tip is reduced to generate a localized jet-like fluid flow in a blood vessel segment adjacent to the conduit tip.

Abstract: The present disclosure relates to medical devices comprising detachable balloons and catheter assemblies, wherein the detachable balloons are polymer balloons, metal balloons, polymer-coated metal balloons, and metalized polymer balloons. Various means of attachment and detachment of the balloons to the catheter assemblies are described. Kits and uses of systems having one or more medical devices, detachable balloons, and elongated or expandable bodies are also disclosed.

Abstract: The present disclosure relates to a rotary blood pump system. The rotary blood pump system may further comprise a double pivot contact bearing system with an operating range between about 50 mL/min and about 1500 mL/min. The rotary blood pump system may also comprise an inflow blood conduit, an outflow conduit, a control system, and a power source. The present disclosure further relates to various inflow conduit assemblies comprising a conduit tip comprised of metal or polymer having an undulating opening surface that provides improved blood flow and washing properties while minimizing regions susceptible to stagnation, and optionally a resilient tip protecting cage structure that reduces the risk of conduit tip suction events and suction-related injury of the wall of adjacent blood vessels or other blood containing structures.

Abstract: The invention relates to a pump-inflow-cannula (1) providing a blood conduit from a heart (2) and/or from an associated vessel to an external blood handling system. The pump-inflow-cannula comprises a body (3), encompassing an essentially axially extending inflow-lumen (4), having a distal-end (5) for an attachment of the inflow-lumen (4) to the blood handling system, and having a proximal-end (6) for an introduction of blood from the heart (2) and/or from the associated vessel into the inflow-lumen (4), wherein at least one projection (7) is provided at the proximal-end (6) to deflect a heart muscle from intruding into the inflow-lumen (4), wherein the body (3) of the pump-inflow-cannula comprises a reinforcement-means (8). The invention is also related to a pump-outflow-cannula (19) and to a blood managing system comprising a pump-inflow-cannula and a pump-outflow-cannula in accordance with the present invention.

Abstract: A clamp can be used to further secure the connection between a flexible tube and a tubing connector and to eliminate or diminish fluid stasis near the connection interface. The clamp can include a hollow member having a passageway extending through the hollow member, an internal thread in the passageway, and a clamping surface in the passageway. The passageway is configured to receive the flexible tube. The internal thread is configured to engage the flexible tube and has a first diameter. The clamping surface has a second diameter less than the first diameter. A hub may be used as an adapter between the clamp and the tube.

Abstract: A clamp can be used to further secure the connection between a flexible tube and a tubing connector and to eliminate or diminish fluid stasis near the connection interface. The clamp can include a hollow member having a passageway extending through the hollow member, an internal thread in the passageway, and a clamping surface in the passageway. The passageway is configured to receive the flexible tube. The internal thread is configured to engage the flexible tube and has a first diameter. The clamping surface has a second diameter less than the first diameter. A hub may be used as an adapter between the clamp and the tube.

Abstract: The invention relates to a pump-inflow-cannula (1) providing a blood conduit from a heart (2) and/or from an associated vessel to an external blood handling system. The pump-inflow-cannula comprises a body (3), encompassing an essentially axially extending inflow-lumen (4), having a distal-end (5) for an attachment of the inflow-lumen (4) to the blood handling system, and having a proximal-end (6) for an introduction of blood from the heart (2) and/or from the associated vessel into the inflow-lumen (4), wherein at least one projection (7) is provided at the proximal-end (6) to deflect a heart muscle from intruding into the inflow-lumen (4), wherein the body (3) of the pump-inflow-cannula comprises a reinforcement-means (8). The invention is also related to a pump-outflow-cannula (19) and to a blood managing system comprising a pump-inflow-cannula and a pump-outflow-cannula in accordance with the present invention.

Abstract: The invention relates to a pump-inflow-cannula (1) providing a blood conduit from a heart (2) and/or from an associated vessel to an external blood handling system. The pump-inflow-cannula comprises a body (3), encompassing an essentially axially extending inflow-lumen (4), having a distal-end (5) for an attachment of the inflow-lumen (4) to the blood handling system, and having a proximal-end (6) for an introduction of blood from the heart (2) and/or from the associated vessel into the inflow-lumen (4), wherein at least one projection (7) is provided at the proximal-end (6) to deflect a heart muscle from intruding into the inflow-lumen (4), wherein the body (3) of the pump-inflow-cannula comprises a reinforcement-means (8). The invention is also related to a pump-outflow-cannula (19) and to a blood managing system comprising a pump-inflow-cannula and a pump-outflow-cannula in accordance with the present invention.

Abstract: A catheter (or cannula) is small enough in diameter to be placed minimally invasively into the body of a patient but also can be expanded post-placement to provide a larger-diameter placed catheter that supports fluid flow at a rate higher than is possible through the pre-placement reduced-diameter catheter. The expandable catheter is constructed using one or more shape memory polymers and can include one or more stent-like sections and/or at least part of the cannula formed as folded lobes. Each of the stent-like sections is configured to enhance the flexibility of the section as compared to the other parts of the catheter and thus allow the section to accommodate tight bends and turns when inserted into the body of the patient. The folded lobes are axial folds that constitute at least one section of the cannula, and they unfold upon expansion of the catheter to create a large cross-sectional shape.

Abstract: The invention relates to a pump-inflow-cannula (1) providing a blood conduit from a heart (2) and/or from an associated vessel to an external blood handling system, said pump-inflow-cannula (1) comprising a body (3), encompassing an inflow-lumen (4), extending essentially axially along a center-line (5), having a distal-end (6) for an attachment of the inflow-lumen (4) to said blood handling system, and having a proximal-end (7) for an introduction of blood from the heart (2) and/or from the associated vessel into the inflow-lumen (4). At the proximal-end (7) at least one angled-hole (8), extending around a longitudinal hole-axis (9) is provided, and said hole-axis (9) includes a presettable hole-angle (?) with the center-line (5) of the inflow-lumen (4), wherein said body (3) of the pump-inflow-cannula (1) comprises a reinforcement-means (10).

Abstract: The invention relates to a pump-inflow-cannula (1) providing a blood conduit from a heart (2) and/or from an associated vessel to an external blood handling system. Said pump-inflow-cannula comprises a body (3), encompassing an essentially axially extending inflow-lumen (4), having a distal-end (5) for an attachment of the inflow-lumen (4) to said blood handling system, and having a proximal-end (6) for an introduction of blood from the heart (2) and/or from the associated vessel into the inflow-lumen (4), wherein at least one projection (7) is provided at the proximal-end (6) to deflect a heart muscle from intruding into the inflow-lumen (4), wherein said body (3) of the pump-inflow-cannula comprises a reinforcement-means (8). The invention is also related to a pump-outflow-cannula (19) and to a blood managing system comprising a pump-inflow-cannula and a pump-outflow-cannula in accordance with the present invention.