Patents by Inventor J. Todd Abrams

J. Todd Abrams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for diagnosis of alzheimer's disease
    Patent number: 7611910
    Abstract: The invention relates to a method of treating Alzheimer's disease in a mammal comprising administering to the mammal an anti-microbial agent having anti-Chlamydia pneumoniae activity. The invention also relates to a method of diagnosing Alzheimer's disease in a mammal comprising measuring the serum anti-Chlamydia pneumoniae antibody titer in a patient suspected of having Alzheimer's disease.
    Type: Grant
    Filed: January 12, 2007
    Date of Patent: November 3, 2009
    Assignee: Intracell, LLC
    Inventors: Brian J. Balin, J. Todd Abrams, Alan P. Hudson, Judith A. Whittum-Hudson
  • Compositions, methods and kits for diagnosis and treatment of infections of the skin and those associated with cutaneous T-cell lymphoma
    Patent number: 7282343
    Abstract: This invention provides methods of diagnosing and treating any C. pneumoniae infection of the skin including C. pneumoniae-associated diseases such as cutaneous T-cell lymphoma (CTCL), mycosis fungoides, Sézary syndrome, lymphomatoid papillosis, Ki-1 lymphoma, exfoliative exematous rash, and digitate parapsoriasis. This invention provides kits that are useful in the methods of the invention as well as for identifying new anti-chlamydial agents in treating skin infections. This invention includes a pharmaceutical vaccine composition comprising an antigen, including a full length antigenic determinant, such as any SAF positive determinant or portion thereof, which produces a detectable immune, humoral and/or cellular response to C. pneumoniae. The invention also includes a method of treating an active CTCL in a living being comprising delivering a therapeutically effective amount of a vaccine, wherein the vaccine comprises an agent, such as an inactivated C.
    Type: Grant
    Filed: October 24, 2001
    Date of Patent: October 16, 2007
    Assignee: Intracell, LLC
    Inventors: J. Todd Abrams, Brian J. Balin
  • METHOD OF DIAGNOSING ALZHEIMER'S DISEASE BY DETECTION OF CHLAMYDIA PNEUMONIAE
    Publication number: 20070135361
    Abstract: The invention relates to a method of treating Alzheimer's disease in a mammal comprising administering to the mammal an anti-microbial agent having anti-Chlamydia pneumoniae activity. The invention also relates to a method of diagnosing Alzheimer's disease in a mammal comprising measuring the serum anti-Chlamydia pneumoniae antibody titer in a patient suspected of having Alzheimer's disease.
    Type: Application
    Filed: January 17, 2007
    Publication date: June 14, 2007
    Inventors: Brian Balin, J. Todd Abrams, Alan Hudson, Judith Whittum-Hudson
  • Treatment and diagnosis of alzheimer's disease
    Patent number: 7189703
    Abstract: The invention relates to a method of treating Alzheimer's disease in a mammal comprising administering to the mammal an anti-microbial agent having anti-Chlamydia pneumoniae activity. The invention also relates to a method of diagnosing Alzheimer's disease in a mammal comprising measuring the serum anti-Chlamydia pneumoniae antibody titer in a patient suspected of having Alzheimer's disease.
    Type: Grant
    Filed: January 8, 1999
    Date of Patent: March 13, 2007
    Assignee: Intracell, LLC
    Inventors: Brian J. Balin, J. Todd Abrams, Alan P. Hudson, Judith A. Whittum-Hudson
  • TREATMENT AND DIAGNOSIS OF ALZHEIMER'S DISEASE
    Publication number: 20010014670
    Abstract: The invention relates to a method of treating Alzheimer's disease in a mammal comprising administering to the mammal an anti-microbial agent having anti-Chlamydia pneumoniae activity. The invention also relates to a method of diagnosing Alzheimer's disease in a mammal comprising measuring the serum anti-Chlamydia pneumoniae antibody titer in a patient suspected of having Alzheimer's disease.
    Type: Application
    Filed: January 8, 1999
    Publication date: August 16, 2001
    Inventors: BRIAN J. BALIN, J. TODD ABRAMS, ALAN P. HUDSON, JUDITH A. WHITTUM-HUDSON
  • Method of activating T cells with lymphokine SAF
    Patent number: 5427781
    Abstract: A lymphokine is taught which can be used to activate and stimulate CD3.sup.+, CD4.sup.+ T cells, as well as Sezary leukemic T cells. The lymphokine can be obtained from mitogen-stimulated peripheral blood mononuclear cells or urine of Sezary Syndrome patients. The lymphokine upregulates interleukin-2 receptors.
    Type: Grant
    Filed: July 2, 1993
    Date of Patent: June 27, 1995
    Assignee: University of Miami
    Inventors: Elaine DeFreitas, J. Todd Abrams
  • Lymphokine SAF and method of making
    Patent number: 5225535
    Abstract: A lymphokine is taught which can be used to activate and stimulate CD3.sup.+, CD4.sup.+ T cells, as well as Sezary leukemic T cells. The lymphokine can be obtained from mitogen-stimulated peripheral blood mononuclear cells or urine of Sezary Syndrome patients. The lymphokine upregulates interleukin-2 receptors.
    Type: Grant
    Filed: December 10, 1990
    Date of Patent: July 6, 1993
    Assignee: The Wistar Institute
    Inventors: Elaine C. DeFreitas, J. Todd Abrams