Patents by Inventor J. Tyler Martin
J. Tyler Martin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240327443Abstract: The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases.Type: ApplicationFiled: June 4, 2024Publication date: October 3, 2024Applicants: ADJUVANCE TECHNOLOGIES, INC., MEMORIAL SLOAN KETTERING CANCER CENTERInventors: David Y. GIN, Eric CHEA, Alberto FERNANDEZ-TEJADA, Jeffrey GARDNER, Jason LEWIS, Philip LIVINGSTON, J. Tyler MARTIN, Lars NORDSTROEM, Naga Vara Kishore PILLARSETTY, Govind RAGUPATHI, Derek TAN
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Patent number: 12037355Abstract: The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases.Type: GrantFiled: March 8, 2023Date of Patent: July 16, 2024Assignees: ADJUVANCE TECHNOLOGIES, INC., MEMORIAL SLOAN KETTERING CANCER CENTERInventors: David Y. Gin, Eric Chea, Alberto Fernandez-Tejada, Jeffrey Gardner, Jason Lewis, Philip Livingston, J. Tyler Martin, Lars Nordstroem, Naga Vara Kishore Pillarsetty, Govind Ragupathi, Derek Tan
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Publication number: 20230357300Abstract: The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases.Type: ApplicationFiled: March 22, 2023Publication date: November 9, 2023Applicant: ADJUVANCE TECHNOLOGIES, INC.Inventors: Amanda CHAN, Jeffrey GARDNER, Lars NORDSTROEM, William WALKOWICZ, J Tyler MARTIN, Weidong ZHANG
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Publication number: 20230263886Abstract: The present application relates to new vaccines, improved vaccine priming, and antigen dose sparing in connection with triterpene glycoside saponin-derived adjuvants, salt forms thereof, and pharmaceutical compositions, as well as related methods.Type: ApplicationFiled: June 17, 2021Publication date: August 24, 2023Inventors: J. Tyler MARTIN, Eric Jon FARRIS, Anna Therese LAMPE
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Publication number: 20230219991Abstract: The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases.Type: ApplicationFiled: March 8, 2023Publication date: July 13, 2023Applicants: ADJUVANCE TECHNOLOGIES, INC., MEMORIAL SLOAN KETTERING CANCER CENTERInventors: David Y. GIN, Eric CHEA, Alberto FERNANDEZ-TEJADA, Jeffrey GARDNER, Jason LEWIS, Philip LIVINGSTON, J. Tyler MARTIN, Lars NORDSTROEM, Naga Vara Kishore PILLARSETTY, Govind RAGUPATHI, Derek TAN
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Publication number: 20230128815Abstract: The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides salt forms, formulations, and pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds, salt forms, or compositions in the treatment of and immunization for infectious diseases.Type: ApplicationFiled: March 23, 2021Publication date: April 27, 2023Inventors: J Tyler MARTIN, Jared William WENGER, Stephan D PARENT, Courtney S JOHNSON, Eric Jon FARRIS, Gui LIU
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Publication number: 20220409721Abstract: The present application relates to compositions capable of inducing an immune response against Varicella zoster virus, methods of administering such compositions, and methods of producing such compositions.Type: ApplicationFiled: November 4, 2020Publication date: December 29, 2022Applicant: ADJUVANCE TECHNOLOGIES, INC.Inventors: J Tyler MARTIN, Jared William WENGER, Eric Jon FARRIS, Patrick J FRENCHICK (Deceased), Anna Therese LAMPE
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Publication number: 20220184207Abstract: The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases and cancers.Type: ApplicationFiled: March 4, 2022Publication date: June 16, 2022Applicant: ADJUVANCE TECHNOLOGIES, INC.Inventors: J Tyler MARTIN, Jeffrey GARDNER
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Patent number: 11324821Abstract: The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases and cancers.Type: GrantFiled: October 15, 2018Date of Patent: May 10, 2022Assignee: ADJUVANCE TECHNOLOGIES, INC.Inventors: J Tyler Martin, Jeffrey Gardner
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Publication number: 20210299237Abstract: The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases.Type: ApplicationFiled: April 13, 2018Publication date: September 30, 2021Applicant: ADJUVANCE TECHNOLOGIES, INC.Inventors: Amanda CHAN, Jeffrey GARDNER, Lars NORDSTROEM, William WALKOWICZ, J Tyler MARTIN, Weidong Zhang
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Publication number: 20210283248Abstract: The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases.Type: ApplicationFiled: April 25, 2018Publication date: September 16, 2021Applicants: Adjuvance Technologies, Inc., Memorial Sloan Kettering Cancer CenterInventors: Philip LIVINGSTON, Govind RAGUPATHI, Jeffrey GARDNER, J Tyler MARTIN
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Patent number: 10906926Abstract: The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases.Type: GrantFiled: March 23, 2020Date of Patent: February 2, 2021Assignees: ADJUVANCE TECHNOLOGIES, INC., MEMORIAL SLOAN KETTERING CANCERInventors: David Y. Gin, Eric Chea, Alberto Fernandez-Tejada, Jeffrey Gardner, Jason Lewis, Philip Livingston, J. Tyler Martin, Lars Nordstroem, Naga Vara Kishore Pillarsetty, Govind Ragupathi, Derek Tan
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Publication number: 20210002316Abstract: The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases.Type: ApplicationFiled: August 27, 2020Publication date: January 7, 2021Applicants: ADJUVANCE TECHNOLOGIES, INC., MEMORIAL SLOAN KETTERING CANCER CENTERInventors: David Y. GIN, Eric CHEA, Alberto FERNANDEZ-TEJADA, Jeffrey GARDNER, Jason LEWIS, Philip LIVINGSTON, J. Tyler MARTIN, Lars NORDSTROEM, Naga Vara Kishore PILLARSETTY, Govind RAGUPATHI, Derek TAN
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Publication number: 20200261571Abstract: The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases and cancers.Type: ApplicationFiled: October 15, 2018Publication date: August 20, 2020Applicant: ADJUVANCE TECHNOLOGIES, INC.Inventors: J Tyler MARTIN, Jeffrey GARDNER
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Publication number: 20200239509Abstract: The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases.Type: ApplicationFiled: March 23, 2020Publication date: July 30, 2020Applicants: ADJUVANCE TECHNOLOGIES, INC., MEMORIAL SLOAN KETTERING CANCER CENTERInventors: David Y. GIN (Deceased), Eric CHEA, Alberto FERNANDEZ-TEJADA, Jeffrey GARDNER, Jason LEWIS, Philip LIVINGSTON, J. Tyler MARTIN, Lars NORDSTROEM, Naga Vara Kishore PILLARSETTY, Govind RAGUPATHI, Derek TAN
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Publication number: 20200164065Abstract: The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases.Type: ApplicationFiled: April 25, 2018Publication date: May 28, 2020Applicant: ADJUVANCE TECHNOLOGIES, INC.Inventors: Jeffrey GARDNER, Philip LIVINGSTON, J Tyler MARTIN
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Publication number: 20180327436Abstract: The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases.Type: ApplicationFiled: November 4, 2016Publication date: November 15, 2018Applicant: ADJUVANCE TECHNOLOGIES, INC.Inventors: David Y. GIN (Deceased), Eric CHEA, Alberto FERNANDEZ-TEJADA, Jeffrey GARDNER, Jason LEWIS, Philip LIVINGSTON, J. Tyler MARTIN, Lars NORDSTROEM, Naga Vara Kishore PILLARSETTY, Govind RAGUPATHI, Derek TAN
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Publication number: 20110281937Abstract: Disclosed herein are engineered zinc finger proteins which modulate transcription of the gene encoding vascular endothelial growth factor-A (VEGF-A) and other genes encoding products with neurotrophic activities. Also disclosed are methods for the use of these engineered zinc finger proteins in the treatment of neuropathy (including diabetic neuropathy), and other types of neural injury and neurodegeneration.Type: ApplicationFiled: January 3, 2011Publication date: November 17, 2011Inventors: J. Tyler Martin, Edward J. Rebar
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Publication number: 20100256221Abstract: Disclosed herein are engineered zinc finger proteins which modulate transcription of the gene encoding vascular endothelial growth factor-A (VEGF-A) and other genes encoding products with neurotrophic activities. Also disclosed are methods for the use of these engineered zinc finger proteins in the treatment of neuropathy (including diabetic neuropathy), and other types of neural injury and neurodegeneration.Type: ApplicationFiled: October 8, 2009Publication date: October 7, 2010Inventor: J. Tyler Martin
