Patents by Inventor J urgen K. Maibaum

J urgen K. Maibaum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • .delta.-amino-.gamma.-hydroxy-.omega.-aryl-alkanoic acid amides
    Patent number: 5627182
    Abstract: .delta.-Amino-.gamma.-hydroxy-.omega.-aryl-alkanoic acid amides of formula I ##STR1## and the salts thereof, have renin-inhibiting properties and can be used as antihypertensive medicinal active ingredients.
    Type: Grant
    Filed: July 25, 1996
    Date of Patent: May 6, 1997
    Assignee: Ciba Geigy Corporation
    Inventors: Richard G oschke, J urgen K. Maibaum, Walter Schilling, Stefan Stutz, Pascal Rigollier, Yasuchika Yamaguchi, Nissim C. Cohen, Peter Herold
  • 3,5-Disubstituted tetrahydrofuran-2-ones
    Patent number: 5606078
    Abstract: Compounds of formula I ##STR1## wherein R.sub.1 is free or esterified carboxy, hydroxymethyl or formyl,R.sub.2 and R.sub.4 are each independently of the other aliphatic, cycloaliphatic-aliphatic, araliphatic or heteroarylaliphatic radicals andR.sub.3 is azido, or amino that is aliphatically or araliphatically substituted and/or protected by an amino-protecting group,and the salts thereof, are valuable intermediates in the preparation of medicinal active ingredients, for example of compounds of formula II ##STR2## wherein R.sub.A is an aromatic or heteroaromatic radical,R.sub.2 and R.sub.4 are each independently of the other aliphatic, cycloaliphatic, cycloaliphaticaliphatic or araliphatic radicals,R.sub.3 is unsubstituted or N-mono- or N,N-di-lower alkylated or N-lower alkanoylated amino, andR.sub.B is an aliphatically, cycloaliphatically or heteroaromatically-aliphatically substituted amino group,and the salts thereof, which can be used, for example, as antihypertensives.
    Type: Grant
    Filed: April 4, 1995
    Date of Patent: February 25, 1997
    Assignee: Ciba-Geigy Corporation
    Inventors: Richard G oschke, Peter Herold, Pascal Rigollier, J urgen K. Maibaum
  • .delta.-amino-.gamma.-hydroxy-.omega.-aryl-alkanoic acid amides
    Patent number: 5559111
    Abstract: .delta.-Amino-.gamma.-hydroxy-.omega.-aryl-alkanoic acid amides of formula I ##STR1## and the salts thereof, have renin-inhibiting properties and can be used as antihypertensive medicinal active ingredients.
    Type: Grant
    Filed: April 4, 1995
    Date of Patent: September 24, 1996
    Assignee: Ciba-Geigy Corporation
    Inventors: Richard G oschke, J urgen K. Maibaum, Walter Schilling, Stefan Stutz, Pascal Rigollier, Yasuchika Yamaguchi, Nissim C. Cohen, Peter Herold