Patents by Inventor J. William Futrell
J. William Futrell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20150376572Abstract: The present invention provides adipose-derived stem cells (ADSCs), adipose-derived stem cell-enriched fractions (ADSC-EF) and adipose-derived lattices, alone and combined with the ADSCs of the invention. In one aspect, the present invention provides an ADSC substantially free of adipocytes and red blood cells and clonal populations of connective tissue stem cells. The ADSCs can be employed, alone or within biologically-compatible compositions, to generate differentiated tissues and structures, both in vivo and in vitro. Additionally, the ADSCs can be expanded and cultured to produce molecules such as hormones, and to provide conditioned culture media for supporting the growth and expansion of other cell populations. In another aspect, the present invention provides a adipose-derived lattice substantially devoid of cells, which includes extracellular matrix material from adipose tissue.Type: ApplicationFiled: December 23, 2014Publication date: December 31, 2015Inventors: Adam J. Katz, Ramon Llull, J. William Futrell, Marc H. Hedrick, Prosper Benhaim, Hermann Peter Lorenz, Min Zhu, Patricia Zuk, Peter H. Ashjian
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Publication number: 20150191698Abstract: The present invention provides adipose-derived stem cells and lattices. In one aspect, the present invention provides a lipo-derived stem cell substantially free of adipocytes and red blood cells and clonal populations of connective tissue stem cells. The cells can be employed, alone or within biologically-compatible compositions, to generate differentiated tissues and structures, both in vivo and in vitro. Additionally, the cells can be expanded and cultured to produce hormones and to provide conditioned culture media for supporting the growth and expansion of other cell populations. In another aspect, the present invention provides a lipo-derived lattice substantially devoid of cells, which includes extracellular matrix material from adipose tissue. The lattice can be used as a substrate to facilitate the growth and differentiation of cells, whether in vivo or in vitro, into anlagen or even mature tissues or structures.Type: ApplicationFiled: March 16, 2015Publication date: July 9, 2015Applicants: The Regents of the University of California, University of Pittsburgh of the Commonwealth System of Higher EducationInventors: Adam J. Katz, Ramon Llull, J. William Futrell, Marc H. Hedrick, Prosper Benhaim, Hermann Peter Lorenz, Min Zhu
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Publication number: 20130224858Abstract: The present invention provides adipose-derived stem cells and lattices. In one aspect, the present invention provides a lipo-derived stem cell substantially free of adipocytes and red blood cells and clonal populations of connective tissue stem cells. The cells can be employed, alone or within biologically-compatible compositions, to generate differentiated tissues and structures, both in vivo and in vitro. Additionally, the cells can be expanded and cultured to produce hormones and to provide conditioned culture media for supporting the growth and expansion of other cell populations. In another aspect, the present invention provides a lipo-derived lattice substantially devoid of cells, which includes extracellular matrix material from adipose tissue. The lattice can be used as a substrate to facilitate the growth and differentiation of cells, whether in vivo or in vitro, into anlagen or even mature tissues or structures.Type: ApplicationFiled: March 28, 2013Publication date: August 29, 2013Inventors: Adam J. Katz, Ramon Llull, J. William Futrell, Marc H. Hedrick, Prosper Benhaim, Hermann Peter Lorenz, Min Zhu
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Publication number: 20130217118Abstract: The present invention provides adipose-derived stem cells (ADSCs), adipose-derived stem cell-enriched fractions (ADSC-EF) and adipose-derived lattices, alone and combined with the ADSCs of the invention. In one aspect, the present invention provides an ADSC substantially free of adipocytes and red blood cells and clonal populations of connective tissue stem cells. The ADSCs can be employed, alone or within biologically-compatible compositions, to generate differentiated tissues and structures, both in vivo and in vitro. Additionally, the ADSCs can be expanded and cultured to produce molecules such as hormones, and to provide conditioned culture media for supporting the growth and expansion of other cell populations. In another aspect, the present invention provides a adipose-derived lattice substantially devoid of cells, which includes extracellular matrix material from adipose tissue.Type: ApplicationFiled: December 12, 2012Publication date: August 22, 2013Inventors: Adam J. Katz, Ramon Llull, J. William Futrell, Marc H. Hedrick, Prosper Benhaim, Hermann Peter Lorenz, Min Zhu, Patricia Zuk
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Publication number: 20120208274Abstract: The present invention provides adipose-derived stem cells (ADSCs), adipose-derived stem cell-enriched fractions (ADSC-EF) and adipose-derived lattices, alone and combined with the ADSCs of the invention. In one aspect, the present invention provides an ADSC substantially free of adipocytes and red blood cells and clonal populations of connective tissue stem cells. The ADSCs can be employed, alone or within biologically-compatible compositions, to generate differentiated tissues and structures, both in vivo and in vitro. Additionally, the ADSCs can be expanded and cultured to produce molecules such as hormones, and to provide conditioned culture media for supporting the growth and expansion of other cell populations. In another aspect, the present invention provides a adipose-derived lattice substantially devoid of cells, which includes extracellular matrix material from adipose tissue.Type: ApplicationFiled: February 29, 2012Publication date: August 16, 2012Inventors: Adam J. Katz, Ramon Llull, J. William Futrell, Marc H. Hedrick, Prosper Benhaim, Hermann Peter Lorenz, Min Zhu, Patricia Zuk, Peter H. Ashjian
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Publication number: 20110318833Abstract: The present invention provides adipose-derived stem cells and lattices. In one aspect, the present invention provides a lipo-derived stem cell substantially free of adipocytes and red blood cells and clonal populations of connective tissue stem cells. The cells can be employed, alone or within biologically-compatible compositions, to generate differentiated tissues and structures, both in vivo and in vitro. Additionally, the cells can be expanded and cultured to produce hormones and to provide conditioned culture media for supporting the growth and expansion of other cell populations. In another aspect, the present invention provides a lipo-derived lattice substantially devoid of cells, which includes extracellular matrix material from adipose tissue. The lattice can be used as a substrate to facilitate the growth and differentiation of cells, whether in vivo or in vitro, into anlagen or even mature tissues or structures.Type: ApplicationFiled: September 6, 2011Publication date: December 29, 2011Inventors: Adam J. Katz, Ramon Llull, J. William Futrell, Marc H. Hedrick, Prosper Benhaim, Hermann Peter Lorenz, Min Zhu
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Publication number: 20110027879Abstract: The present invention provides adipose-derived stem cells (ADSCs), adipose-derived stem cell-enriched fractions (ADSC-EF) and adipose-derived lattices, alone and combined with the ADSCs of the invention. In one aspect, the present invention provides an ADSC substantially free of adipocytes and red blood cells and clonal populations of connective tissue stem cells. The ADSCs can be employed, alone or within biologically-compatible compositions, to generate differentiated tissues and structures, both in vivo and in vitro. Additionally, the ADSCs can be expanded and cultured to produce molecules such as hormones, and to provide conditioned culture media for supporting the growth and expansion of other cell populations. In another aspect, the present invention provides a adipose-derived lattice substantially devoid of cells, which includes extracellular matrix material from adipose tissue.Type: ApplicationFiled: January 26, 2010Publication date: February 3, 2011Inventors: Adam J. Katz, Ramon Llull, J. William Futrell, Marc H. Hedrick, Prosper Benhaim, Hermann Peter Lorenz, Min Zhu, Patricia Zuk, Peter H. Ashjian
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Publication number: 20100173411Abstract: The present invention provides adipose-derived stem cells and lattices. In one aspect, the present invention provides a lipo-derived stem cell substantially free of adipocytes and red blood cells and clonal populations of connective tissue stem cells. The cells can be employed, alone or within biologically-compatible compositions, to generate differentiated tissues and structures, both in vivo and in vitro. Additionally, the cells can be expanded and cultured to produce hormones and to provide conditioned culture media for supporting the growth and expansion of other cell populations. In another aspect, the present invention provides a lipo-derived lattice substantially devoid of cells, which includes extracellular matrix material from adipose tissue. The lattice can be used as a substrate to facilitate the growth and differentiation of cells, whether in vivo or in vitro, into anlagen or even mature tissues or structures.Type: ApplicationFiled: December 18, 2009Publication date: July 8, 2010Inventors: Adam J. Katz, Ramon Llull, J. William Futrell, Marc H. Hedrick, Prosper Benhaim, Hermann Peter Lorenz, Min Zhu
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Publication number: 20100016729Abstract: A system including a medical instrument, a sensor, and a processor module in communication with the sensor. The medical instrument includes a radiation source for transmitting electromagnetic radiation from within a body and through a material in the body. The sensor receives a portion of the electromagnetic radiation transmitted through the material, and the processor module determines at least one characteristic of the material based on the electromagnetic radiation received by the sensor.Type: ApplicationFiled: June 4, 2007Publication date: January 21, 2010Inventor: J. William Futrell
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Publication number: 20090181456Abstract: The present invention provides adipose-derived stem cells (ADSCs), adipose-derived stem cell-enriched fractions (ADSC-EF) and adipose-derived lattices, alone and combined with the ADSCs of the invention. In one aspect, the present invention provides an ADSC substantially free of adipocytes and red blood cells and clonal populations of connective tissue stem cells. The ADSCs can be employed, alone or within biologically-compatible compositions, to generate differentiated tissues and structures, both in vivo and in vitro. Additionally, the ADSCs can be expanded and cultured to produce molecules such as hormones, and to provide conditioned culture media for supporting the growth and expansion of other cell populations. In another aspect the present invention provides a adipose-derived lattice substantially devoid of cells, which includes extracellular matrix material from adipose tissue.Type: ApplicationFiled: December 8, 2008Publication date: July 16, 2009Inventors: Marc H. Hedrick, Adam J. Katz, Ramon Lluil, J. William Futrell, Prosper Benhaim, Hermann Peter Lorenz, Min Zhu
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Patent number: 7470537Abstract: The present invention provides adipose-derived stem cells (ADSCs), adipose-derived stem cell-enriched fractions (ADSC-EF) and adipose-derived lattices, alone and combined with the ADSCs of the invention. In one aspect, the present invention provides an ADSC substantially free of adipocytes and red blood cells and clonal populations of connective tissue stem cells. The ADSCs can be employed, alone or within biologically-compatible compositions, to generate differentiated tissues and structures, both in vivo and in vitro. Additionally, the ADSCs can be expanded and cultured to produce molecules such as hormones, and to provide conditioned culture media for supporting the growth and expansion of other cell populations. In another aspect, the present invention provides an adipose-derived lattice substantially devoid of cells, which includes extracellular matrix material from adipose tissue.Type: GrantFiled: December 17, 2003Date of Patent: December 30, 2008Inventors: Marc H. Hedrick, Adam J. Katz, Ramón Llull, J. William Futrell, Prosper Benhaim, Hermann Peter Lorenz, Min Zhu
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Publication number: 20040171146Abstract: The present invention provides adipose-derived stem cells and lattices. In one aspect, the present invention provides a lipo-derived stem cell substantially free of adipocytes and red blood cells and clonal populations of connective tissue stem cells. The cells can be employed, alone or within biologically-compatible compositions, to generate differentiated tissues and structures, both in vivo and in vitro. Additionally, the cells can be expanded and cultured to produce hormones and to provide conditioned culture media for supporting the growth and expansion of other cell populations. In another aspect the present invention provides a lipo-derived lattice substantially devoid of cells, which includes extracellular matrix material from adipose tissue. The lattice can be used as a substrate to facilitate the growth and differentiation of cells, whether in vivo or in vitro, into anlagen or even mature tissues or structures.Type: ApplicationFiled: March 9, 2004Publication date: September 2, 2004Applicants: University of Pittsburgh of the Commonwealth System of Higher Education, The Regents of the University of CaliforniaInventors: Adam J. Katz, Ramon Llull, J. William Futrell, Marc H. Hedrick, Prosper Benhaim, Hermann Peter Lorenz, Min Zhu
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Publication number: 20030082152Abstract: The present invention provides adipose-derived stem cells (ADSCs), adipose-derived stem cell-enriched fractions (ADSC-EF) and adipose-derivedlattices, alone and combined with the ADSCs of the invention. In one aspect, the present invention provides an ADSC substantially free of adipocytes and red blood cells and clonal populations of connective tissue stem cells. The ADSCs can be employed, alone or within biologically-compatible compositions, to generate differentiated tissues and structures, both in vivo and in vitro. Additionally, the ADSCs can be expanded and cultured to produce molecules such as hormones, and to provide conditioned culture media for supporting the growth and expansion of other cell populations. In another aspect, the present invention provides a adipose-derived lattice substantially devoid of cells, which includes extracellular matrix material from adipose tissue.Type: ApplicationFiled: September 10, 2001Publication date: May 1, 2003Inventors: Marc H. Hedrick, Adam J. Katz, Ramon Llull, J. William Futrell, Prosper Benhaim, Hermann Peter Lorenz, Min Zhu
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Publication number: 20020076400Abstract: The present invention provides adipose-derived stem cells and lattices. In one aspect, the present invention provides a lipo-derived stem cell substantially free of adipocytes and red blood cells and clonal populations of connective tissue stem cells. The invention also provides a method of isolating stem cells from adipose tissues. The cells can be employed, alone or within biologically-compatible compositions, to generate differentiated tissues and structures, both in vivo and in vitro. Additionally, the cells can be expanded and cultured to produce hormones and to provide conditioned culture media for supporting the growth and expansion of other cell populations. In another aspect, the present invention provides a lipo-derived lattice substantially devoid of cells, which includes extracellular matrix material from adipose tissue. The lattice can be used as a substrate to facilitate the growth and differentiation of cells, whether in vivo or in vitro, into anlagen or even mature tissues or structures.Type: ApplicationFiled: September 6, 2001Publication date: June 20, 2002Applicant: University of Pittsburgh of the Commonwealth System of Higher EducationInventors: Adam J. Katz, Ramon Llull, J. William Futrell, Marc H. Hedrick, Prosper Benhaim, Hermann Peter Lorenz, Min Zhu
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Patent number: 6316247Abstract: A device and method for producing refined adipose tissue for use in autologous adipose transplantation or research wherein a sterile environment is maintained. More particularly, a system for refining tissue comprising a first flexible container, a second flexible container having a plurality of pores providing for fluid communication between the interior of the first flexible container and the interior of the first enveloping flexible container, a first port that provides communication between the exterior environment and the interior of the first flexible container and thereby provides a means for introducing fluids into the interior of the first flexible container and allowing waste effluent to exit the first container, a second flexible container, a second port for inserting tissue into the second container and expressing refined tissue out of the container, and a means for controlling the opening and closing of the first and second ports.Type: GrantFiled: June 15, 1999Date of Patent: November 13, 2001Assignee: University of PittsburghInventors: Adam J. Katz, Ramon Llull, J. William Futrell, Marc H. Hedrick, Frank R. Walters
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Patent number: 5352194Abstract: The present invention provides a device for performing suction lipectomy or liposuction in which the reciprocal motion required during the liposuction procedure is automated. This automation greatly reduces the physical exertion required of the operating surgeon. The present invention also allows the use of smaller cannulae to achieve an improved aesthetic result. Use of such smaller cannulae with the manual liposuction procedures currently in use would be extremely taxing if not impossible.Type: GrantFiled: June 29, 1992Date of Patent: October 4, 1994Assignee: University of PittsburghInventors: Richard J. Greco, Mark B. Freidman, J. William Futrell