Patents by Inventor J. William Lown

J. William Lown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Perylenequinones for use as sonosensitizers
    Patent number: 6627664
    Abstract: The invention is perylenequinones that are both sonosensitizers and photosensitizers, and their therapeutic use.
    Type: Grant
    Filed: January 30, 2001
    Date of Patent: September 30, 2003
    Assignee: Altachem Pharma Ltd.
    Inventors: Gerald G. Miller, J. William Lown
  • Perylenequinones for use as photosensitizers and sonosensitizers
    Publication number: 20020143066
    Abstract: The invention is perylenequinones that are both sonosensitizers and photosensitizers, and their therapeutic use.
    Type: Application
    Filed: January 30, 2001
    Publication date: October 3, 2002
    Inventors: Gerald G. Miller, J. William Lown
  • Oligopeptide antiretroviral agents
    Patent number: 5616606
    Abstract: Oligopeptide antiretroviral agents are represented by formula (I), wherein A is a moiety bearing a positive charge and of a size which avoids steric inhibition of binding of said compound to nucleic acid sequences associated with the cellular activity of retroviruses; R.sub.1 is a moiety derived from a dicarboxylic acid; Hew is a five-membered heterocyclic moiety; y and z are independently 0, 1, 2 or 3; and x is 0 or 1. These compounds exhibit antiretroviral activity, especially against Human Immunodeficiency Virus (HIV).
    Type: Grant
    Filed: August 2, 1995
    Date of Patent: April 1, 1997
    Assignees: Synphar Laboratories, Inc., Taiho Pharmaceutical Co., Ltd.
    Inventors: J. William Lown, Ronald G. Micetich
  • Cyclopropylpyrroloindole-oligopeptide anticancer agents
    Patent number: 5502068
    Abstract: The invention is directed to novel cyclopropylpyrroloindole-oligopeptide compounds which are useful as anticancer agents. The novel cyclopropylpyrroloindole-oligopeptide compounds have the following general structure: ##STR1## wherein, Het.sup.1 and Het.sup.2 are individually selected from the group consisting of pyrrole, imidazole, triazole, thiophene, furan, thiazole, oxazole and pyrazole,R is selected from the group consisting of a valence bond; a C.sub.1 -C.sub.6 alkyl; a C.sub.2 -C.sub.6 alkenyl; a C.sub.2 -C.sub.6 alkynyl; and an ortho, meta or para linked aromatic group,A is selected from the group consisting of a C.sub.1 -C.sub.6 alkyl group; an amidine or derivative thereof; a guanidine; a secondary, tertiary or quaternary ammonium salt; and a sulfonium salt,n is 0 to 3, andm is 0 to 3.
    Type: Grant
    Filed: January 31, 1995
    Date of Patent: March 26, 1996
    Assignee: Synphar Laboratories, Inc.
    Inventors: J. William Lown, Yuqiang Wang, Weide Luo
  • Oligopeptide anticancer and antiviral agents
    Patent number: 4912199
    Abstract: Oligopeptide anticancer and antiviral agents are represented by the formula:A-(NHCO).sub.m -Het-(NHCO-Het).sub.n -NH-R-NH-(Het-CONH).sub.n -Het-(CONH).sub.m -Awherein A is a moiety bearing a positive charge and of a size which avoids steric inhibition of binding of said compound to deoxyribonucleic acid sequence; R is a moiety derived from a dicarboxylic acid; Het is a five-membered heterocyclic moiety; n is 1, 2 or 3, m is 0 or 1. These compounds exhibit antiviral activity especially against herpes simplex I and II, vaccinia viruses and anticancer activity against several animal and human tumor lines.
    Type: Grant
    Filed: July 15, 1987
    Date of Patent: March 27, 1990
    Assignee: The Governors of the University of Alberta
    Inventors: J. William Lown, Krzysztof Krowicki