Patents by Inventor József Mandl

József Mandl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for treating NASH and for preventing NASH-induced HCC
    Patent number: 11357768
    Abstract: Disclosed are methods of treating non-alcoholic steatohepatitis (NASH) and methods of preventing NASH-induced hepatocellular carcinoma (HCC), such methods including administering O-(3-piperidino-2-hydroxy-1-propyl)-nicotinic amidoxime (BGP15), alone or in combination with a inhibitor of the interleukin-6 receptor transsignaling response, particularly gp130Fc.
    Type: Grant
    Filed: June 8, 2018
    Date of Patent: June 14, 2022
    Assignee: N-GENE RESEARCH LABORATORIES, INC.
    Inventors: Mark Anthony Febbraio, Jozsef Mandl
  • METHODS FOR TREATING NASH AND FOR PREVENTING NASH-INDUCED HCC
    Publication number: 20200179363
    Abstract: Disclosed are methods of treating non-alcoholic steatohepatitis (NASH) and methods of preventing NASH-induced hepatocellular carcinoma (HCC), such methods including administering O-(3-piperidino-2-hydroxy-1-propyl)-nicotinic amidoxime (BGP15), alone or in combination with a inhibitor of the interleukin-6 receptor transsignaling response, particularly gp130Fc.
    Type: Application
    Filed: June 8, 2018
    Publication date: June 11, 2020
    Inventors: Mark Anthony FEBBRAIO, Jozsef MANDL
  • Prevention of Obesity in Antipsychotic, Antidepressant and Antiepileptic Medication
    Publication number: 20150366852
    Abstract: O-(3-piperidino-2-hydroxypropyl)-nicotinic amidoxime or a pharmaceutically suitable acid addition salt thereof (BGP-15) can be used for the prevention or reduction of weight gain or obesity in a patient treated with an antipsychotic drug or an antidepressant drug or an antiepileptic drug.
    Type: Application
    Filed: June 23, 2015
    Publication date: December 24, 2015
    Inventors: Peter Literati Nagy, Jesse Roth, Zoltan Szilvassy, Kalman Tory, Michael Brownstein, Kálmán Takács, Laszlo Vigh, József Mandl, Balázs Sümegi, Sandor Bernath, Attila Kolonics, Gábor Balogh, Janos Egri
  • Prevention of Obesity in Antipsychotic, Antidepressant and Antiepileptic Medication
    Publication number: 20100311719
    Abstract: O-(3-piperidino-2-hydroxypropyl)-nicotinic amidoxime or a pharmaceutically suitable acid addition salt thereof (BGP-15) can be used for the prevention or reduction of weight gain or obesity in a patient treated with an antipsychotic drug or an antidepressant drug or an antiepileptic drug.
    Type: Application
    Filed: August 17, 2010
    Publication date: December 9, 2010
    Inventors: Péter Literáti Nagy, Jesse Roth, Zoltán Szilvássy, Kálmán Tory, Mike Brownstein, Kálmán Takács, László Vígh, József Mandl, Balázs Sümegi, Sándor Bernáth, Attila Kolonics, Gábor Balogh, János Egri
  • Prevention and treatment of obesity
    Patent number: 7763601
    Abstract: O-(3-piperidino-2-hydroxypropyl)-nicotinic amidoxime (BGP-15) or a pharmaceutically suitable acid addition salt thereof can be used for the prevention or reduction of weight gain or the reduction of the rate of body weight gain.
    Type: Grant
    Filed: March 19, 2007
    Date of Patent: July 27, 2010
    Assignee: N-Gene Research Laboratories, Inc.
    Inventors: Péter Literáti Nagy, Zoltán Szilvássy, Kálmán Tory, László Vígh, Kálmán Takács, József Mandl, Balázs Sümegi, Sándor Bernáth, Attila Kolonics, Gábor Balogh, János Egri
  • Prevention and Treatment of Obesity
    Publication number: 20080108673
    Abstract: O-(3-piperidino-2-hydroxypropyl)-nicotinic amidoxime or a pharmaceutically suitable acid addition salt thereof (BGP-15) can be used for the prevention or reduction of weight gain or the reduction of the rate of body weight.
    Type: Application
    Filed: March 19, 2007
    Publication date: May 8, 2008
    Inventors: Peter Literati Nagy, Zoltan Szilvassy, Kalman Tory, Laszlo Vigh, Kalman Takacs, Jozsef Mandl, Balazs Sumegi, Sandor Bernath, Attila Kolonics, Gabor Balogh, Janos Egri