Patents by Inventor József Répási

József Répási has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polymorph form of (r)-2-[2-amino-3-(indol-3-yl)propionylamino]-2- methylpropionic acid and uses thereof
    Patent number: 11891455
    Abstract: This intention relates to a novel polymorph form of compound (R)-2-[2-amino-3-(indol-3-yl)propionylamino]-2-methylpropionic acid, a process for making the novel polymorph form of the compound, and uses thereof for making other polymorph forms of the compound. The invention further relates to composition comprising novel polymorph form of the compound and a pharmaceutically acceptable carrier or excipient.
    Type: Grant
    Filed: September 23, 2020
    Date of Patent: February 6, 2024
    Inventors: Jozsef Repasi, Andras Szabo, Markus Henrich
  • Pharmaceutically effective compounds inhibiting selectively the myosin 2 isoforms
    Patent number: 11845758
    Abstract: The present invention relates to compounds of formula (I) or (II) pharmaceutically acceptable salts, solvates, tautomers, stereoisomers thereof, including enantiomers, diastereomers, racemic mixtures, mixtures of enantiomers, or combinations thereof, and pharmaceutical uses of the compounds.
    Type: Grant
    Filed: June 30, 2023
    Date of Patent: December 19, 2023
    Assignees: PRINTNET KERESKEDELMI ÉS SZOLGÁLTATÓ KFT., EÖTVÖS LORÁND TUDOMÁNYEGYETEM
    Inventors: András Málnási-Csizmadia, Máté Gyimesi, András Szabó, Péter Hári, Suthar Sharad Kumar, Mihály Kovács, Ádám István Horváth, Máté Pénzes, István Lörincz, László Végner, Zoltán Simon, Sándor Bátori, Zoltán Szönyegi, Vajik Horváth, József Répási
  • PHARMACEUTICALLY EFFECTIVE COMPOUNDS INHIBITING SELECTIVELY THE MYOSIN 2 ISOFORMS
    Publication number: 20230339959
    Abstract: The present invention relates to compounds of formula (I) or (II) pharmaceutically acceptable salts, solvates, tautomers, stereoisomers thereof, including enantiomers, diastereomers, racemic mixtures, mixtures of enantiomers, or combinations thereof, and pharmaceutical uses of the compounds.
    Type: Application
    Filed: June 30, 2023
    Publication date: October 26, 2023
    Inventors: András MÁLNÁSI-CSIZMADIA, Máté GYIMESI, András SZABÓ, Péter HÁRI, Suthar Sharad KUMAR, Mihály KOVÁCS, Ádám István HORVÁTH, Máté PÉNZES, István LORINCZ, László VÉGNER, Zoltán SIMON, Sándor BÁTORI, Zoltán SZONYEGI, Vajik HORVÁTH, József RÉPÁSI
  • Pharmaceutically effective compounds inhibiting selectively the myosin 2 isoforms
    Patent number: 11746112
    Abstract: The present invention relates to compounds of formula (I) or (II) pharmaceutically acceptable salts, solvates, tautomers, stereoisomers thereof, including enantiomers, diastereomers, racemic mixtures, mixtures of enantiomers, or combinations thereof, and pharmaceutical uses of the compounds.
    Type: Grant
    Filed: April 18, 2019
    Date of Patent: September 5, 2023
    Assignees: EÖTVÖS LORÁND TUDOMÁNYEGYETEM, PRINTNET KERESKEDELMI ÉS SZOLGÁLTATÓ KFT.
    Inventors: András Málnási-Csizmadia, Maté Gyimesi, András Szabó, Péter Hári, Suthar Sharad Kumar, Mihály Kovács, Ádám István Horváth, Máté Pénzes, István Lörincz, László Végner, Zoltán Simon, Sándor Bátori, Zoltán Szönyegi, Vajk Horváth, József Répási
  • CRYSTALLINE FORMS OF SOLVATES OF TRYPTOPHAN DERIVATIVES, COMPOSITIONS COMPRISING THEM AND USES THEREOF
    Publication number: 20230242483
    Abstract: The invention provides crystalline forms of solvates of tryptophan derivatives of compound (1), compositions comprising them, processes for their preparations and methods of use thereof.
    Type: Application
    Filed: May 23, 2021
    Publication date: August 3, 2023
    Applicant: Galimedix Therapeutics Inc.
    Inventors: Jozsef Jozsef REPASI REPASI, Andras SZABO, Hermann Kurt RUSS, Markus HENRICH
  • NOVEL POLYMORPH FORM OF (R)-2-[2-AMINO-3-(INDOL-3-YL)PROPIONYLAMINO]-2-METHYLPROPIONIC ACID AND USES THEREOF
    Publication number: 20220389056
    Abstract: This intention relates to a novel polymorph form of compound (R)-2-[2-amino-3-(indol-3-yl)propionylamino]-2-methylpropionic acid, a process for making the novel polymorph form of the compound, and uses thereof for making other polymorph forms of the compound. The invention further relates to composition comprising novel polymorph form of the compound and a pharmaceutically acceptable carrier or excipient.
    Type: Application
    Filed: September 23, 2020
    Publication date: December 8, 2022
    Applicant: Galimedix Therapeutics Inc.
    Inventors: Jozsef REPASI, Andras SZABO, Markus HENRICH
  • PHARMACEUTICALLY EFFECTIVE COMPOUNDS INHIBITING SELECTIVELY THE MYOSIN 2 ISOFORMS
    Publication number: 20210087201
    Abstract: The present invention relates to compounds of formula (I) or (II) pharmaceutically acceptable salts, solvates, tautomers, stereoisomers thereof, including enantiomers, diastereomers, racemic mixtures, mixtures of enantiomers, or combinations thereof, and pharmaceutical uses of the compounds.
    Type: Application
    Filed: April 18, 2019
    Publication date: March 25, 2021
    Inventors: András MÁLNÁSI-CSIZMADIA, Máté GYIMESI, András SZABÓ, Péter HÁRI, Suthar Sharad KUMAR, Mihály KOVÁCS, Ádám István HORVÁTH, Máté PÉNZES, István LORINCZ, László VÉGNER, Zoltán SIMON, Sándor BÁTORI, Zoltán SZONYEGI, Vajk HORVÁTH, József RÉPÁSI
  • PROCESS FOR THE SYNTHESIS OF (2E, 4E, 6Z, 8E)-8-(3,4-DIHYDRONAPHTHALEN-1(2H)-YLIDENE)-3,7-DIMETHYLOCTA-2, 4, 6-TRIENOIC ACID
    Publication number: 20190047933
    Abstract: This invention relates to a novel method for the synthesis of (2E,4E,6Z,8E)-8-(3,4-dihydronaphthalen-1(2H)-ylidene)-3,7-dimethylocta-2,4,6-trienoic acid.
    Type: Application
    Filed: March 15, 2017
    Publication date: February 14, 2019
    Inventors: Ulrich Abel, József Répási, András Szabó, Cserépi Stefánia Szücsné, Ádám Bor
  • Pyrrolopyridine-2-carboxylic acid amide derivative useful as inhibitor of glycogen phosphorylase
    Patent number: 8664397
    Abstract: The present invention is directed to a novel form of a pyrrolopyridine-2-carboxylic acid amide of formula (I), which is an inhibitor of glycogen phosphorylase, compositions containing it and their use in therapy. The invention is also directed to processes for production of the novel form, novel intermediates used in said processes and processes for the production of said intermediates.
    Type: Grant
    Filed: December 2, 2005
    Date of Patent: March 4, 2014
    Assignee: Prosidion Limited
    Inventors: Jozsef Repasi, Andras Szabo
  • PROCESSES FOR PREPARING CINACALCET HYDROCHLORIDE AND POLYMORPHIC FORMS THEREOF
    Publication number: 20110295037
    Abstract: The invention relates to cinacalcet hydrochloride, new polymorphic crystalline forms of cinacalcet hydrochloride, amorphous cinacalcet hydrochloride and synthetic processes for their preparation.
    Type: Application
    Filed: June 8, 2007
    Publication date: December 1, 2011
    Applicant: MEDICHEM, S.A.
    Inventors: Tibor Szekeres, Jozsef Repasi, Andras Szabo, Monica Benito Velez, Bernardino Mangion
  • PROCESSES FOR PREPARING INTERMEDIATE COMPOUNDS USEFUL FOR THE PREPARATION OF CINACALCET
    Publication number: 20100267988
    Abstract: The invention relates, in general, to an improved process for preparing compounds (e.g., 3-(3-trifluoromethylphenyl)propanal (Compound III, below)), which are key intermediates for the synthesis of cinacalcet, its salts and/or solvates thereof, as well as the use of such compounds prepared by such process for the preparation of cinacalcet and/or its salts or solvates.
    Type: Application
    Filed: June 8, 2007
    Publication date: October 21, 2010
    Applicant: Medichem, S.A.
    Inventors: Tibor Szekeres, Jozsef Repasi, Andras Szabo, Bernardino Mangion
  • Pyrrolopyridine-2-Carboxylic Acid Amide Derivative Useful as Inhibitor of Glycogen Phosphorylase
    Publication number: 20080293761
    Abstract: The present invention is directed to a novel form of a pyrrolopyridine-2-carboxylic acid amide of formula (I), which is an inhibitor of glycogen phosphorylase, compositions containing it and their use in therapy. The invention is also directed to processes for production of the novel form, novel intermediates used in said processes and processes for the production of said intermediates.
    Type: Application
    Filed: December 2, 2005
    Publication date: November 27, 2008
    Inventors: Jozsef Repasi, Andras Szabo