Abstract: A mechanical ventilation device includes an electronic controller (13) configured to: receive imaging data (22) and ventilator data associated with lungs of a patient while the patient undergoes mechanical ventilation therapy with an associated mechanical ventilator (2); determine a respiratory pressure of the patient based at least on the received ventilator data; determine a lung volume and a lung flow for at least one region of the lungs based on lung sliding data determined from the received imaging data and the determined respiratory pressure; determine a regional resistance and elastance for the at least one region of the lungs from the lung volume and the lung flow for the at least one region; and display the regional resistance and elastance for the at least one region of the lungs on a display device (14).

Abstract: The invention relates to methods for identifying fungicides, to nucleic acids which encode fungal polypeptides with the biological activity of glyoxal oxidases, to the polypeptides encoded by them, to their use as targets for fungicides, their use for identifying new fungicidally active compounds, to methods for finding modulators of these polypeptides, and to transgenic organisms containing these polyypeptides.