Patents by Inventor Jacek K. Pinski

Jacek K. Pinski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CAR T-CELL THERAPY DIRECTED TO LHR FOR THE TREATMENT OF SOLID TUMORS
    Publication number: 20250129171
    Abstract: Provided herein are novel anti-LHR chimeric antigen receptor (CAR), cells or compositions comprising the same, vector or plasmid encoding anti-LHR CAR, and methods for producing the same, or using the same for detecting or treating ovarian cancer or prostate cancer. Also provided herein are anti-LHR antibody, compositions comprising the same, nucleic acid sequence encoding the same, and a kit for detecting LHR.
    Type: Application
    Filed: May 20, 2024
    Publication date: April 24, 2025
    Inventors: Alan L. Epstein, Peisheng Hu, Jacek K. Pinski
  • CAR T-CELL THERAPY DIRECTED TO LHR FOR THE TREATMENT OF SOLID TUMORS
    Publication number: 20210403585
    Abstract: Provided herein are novel anti-LHR chimeric antigen receptor (CAR), cells or compositions comprising the same, vector or plasmid encoding anti-LHR CAR, and methods for producing the same, or using the same for detecting or treating ovarian cancer or prostate cancer. Also provided herein are anti-LHR antibody, compositions comprising the same, nucleic acid sequence encoding the same, and a kit for detecting LHR.
    Type: Application
    Filed: August 31, 2021
    Publication date: December 30, 2021
    Inventors: Alan L. Epstein, Peisheng Hu, Jacek K. Pinski
  • Car t-cell therapy directed to LHR for the treatment of solid tumors
    Patent number: 11136401
    Abstract: Provided herein are novel anti-LHR chimeric antigen receptor (CAR), cells or compositions comprising the same, vector or plasmid encoding anti-LHR CAR, and methods for producing the same, or using the same for detecting or treating ovarian cancer or prostate cancer. Also provided herein are anti-LHR antibody, compositions comprising the same, nucleic acid sequence encoding the same, and a kit for detecting LHR.
    Type: Grant
    Filed: March 25, 2016
    Date of Patent: October 5, 2021
    Assignee: University of Southern California
    Inventors: Alan L. Epstein, Peisheng Hu, Jacek K. Pinski
  • CAR T-CELL THERAPY DIRECTED TO LHR FOR THE TREATMENT OF SOLID TUMORS
    Publication number: 20180112003
    Abstract: Provided herein are novel anti-LHR chimeric antigen receptor (CAR), cells or compositions comprising the same, vector or plasmid encoding anti-LHR CAR, and methods for producing the same, or using the same for detecting or treating ovarian cancer or prostate cancer. Also provided herein are anti-LHR antibody, compositions comprising the same, nucleic acid sequence encoding the same, and a kit for detecting LHR.
    Type: Application
    Filed: March 25, 2016
    Publication date: April 26, 2018
    Applicant: University of Southern California
    Inventors: Alan L. Epstein, Peisheng Hu, Jacek K. Pinski
  • COMPOSITIONS AND METHODS FOR REGULATING CANCER-RELATED SIGNALING PATHWAYS
    Publication number: 20140348744
    Abstract: The use of luteinizing hormone receptor (LHR) as a treatment target in cancer is provided. Data demonstrates that LHR plays an important role in androgen synthesis and signaling pathways critical for prostate cancer progression. When LHR is silenced, there is a significant downregulation of androgen receptor (AR) mRNA and protein expression with a subsequent suppression of PSA expression. Data suggesting that the LH-LHR signaling cascade may be an upstream and viable therapeutic target in castration-resistant prostate cancer (CRPC) is presented.
    Type: Application
    Filed: May 27, 2014
    Publication date: November 27, 2014
    Inventor: Jacek K. Pinski