Patents by Inventor Jacek Krzeminski

Jacek Krzeminski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR MODIFYING BACTERIAL GENE EXPRESSION
    Publication number: 20230405130
    Abstract: Provided herein are compositions and methods for treating and preventing bacterial infections. In particular, provided herein are targeted bola-amphiphile: nucleic acid complexes specific for bacteria.
    Type: Application
    Filed: November 5, 2021
    Publication date: December 21, 2023
    Inventors: David B. Stewart, Gayatri Vedantam, Arun K. Sharma, Jacek KRZEMINSKI
  • 2'-"up" fluorinated 2'-deoxy-arabinofuranosylpurines
    Patent number: 5750675
    Abstract: The present invention provides a compound having the structure: ##STR1## wherein R.sup.1 is hydrogen, benzyl or a substituted benzyl group;X is hydrogen, a flouro, an amino or a substituted amino group;Y is hydrogen, a methoxy, a methylthio, a benzylthio, a methylethyl, a chloro, an amino or a substituted amino group; andY' is an oxo or a thio group; andZ is hydrogen, a hydroxy, a methoxy, a halogen, an amino or a substituted amino group.The present invention also provides a method of synthesizing a compound having the above-identified structure as well as the intermediate compounds produced according to that method.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: May 12, 1998
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Kyoichi A. Watanabe, Krzysztof W. Pankiewicz, Jacek Krzeminski, Barbara Nawrot
  • Synthesis of 2'-"up" fluorinated 2'-deoxy-arabinofuranosyl purines
    Patent number: 5525720
    Abstract: The present invention provides a compound having the structure: ##STR1## wherein R.sup.1 is hydrogen, benzyl or a substituted benzyl group;X is hydrogen, a flouro, an amino or a substituted amino group;Y is hydrogen, a methoxy, a methylthio, a benzylthio, a methylethyl, a chloro, an amino or a substituted amino group; andY' is an oxo or a thio group; andZ is hydrogen, a hydroxy, a methoxy, a halogen, an amino or a substituted amino group.The present invention also provides a method of synthesizing a compound having the above-identified structure as well as the intermediate compounds produced according to that method.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: June 11, 1996
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Kyoichi A. Watanabe, Krzysztof W. Pankiewicz, Jacek Krzeminski, Barbara Nawrot