Abstract: A multimodal apparatus for analysis of allergic reactions during skin tests and a method of multispectral imaging of allergic reactions in case of the type I and the type IV allergic reactions induced by performing skin allergy Prick and Patch tests combine thermal imaging with Laser Doppler flowmetry or 3D scanning to confirm the results of epidermal hyperthermia tests.

Abstract: A passive planar thermo-optical structure for detection of a region of changed temperature on patient's skin is provided. The thermo-optical structure has a layered structure including a transparent film layer, a thermochromic layer, a securing layer, an adhesive layer, and a protective layer. At least one dye in the thermochromic layer is above a temperature threshold range of 31°-37° C., which adopts the first colour and keeps it in a temperature range greater than or equal to 0.6° C. A width of this temperature range, in which the colour is indefinite, is smaller than 0.3° C. A method of diagnosing allergy using the above-structure is provided. The method includes the steps of stimulation, measurement and comparison. After stimulating three regions of patient's skin, an evaluation of extent of histamine reaction is performed. Then, the extent of histamine reaction in the third region is compared to that in the first and second regions.

Abstract: A passive planar thermo-optical structure for detection of a region of changed temperature on patient's skin is provided. The thermo-optical structure has a layered structure including a transparent film layer, a thermochromic layer, a securing layer, an adhesive layer, and a protective layer. At least one dye in the thermochromic layer is above a temperature threshold range of 31°-37° C., which adopts the first color and keeps it in a temperature range greater than or equal to 0.6° C. A width of this temperature range, in which the color is indefinite, is smaller than 0.3° C. A method of diagnosing allergy using the above-structure is provided. The method includes the steps of stimulation, measurement and comparison. After stimulating three regions of patient's skin, an evaluation of extent of histamine reaction is performed. Then, the extent of histamine reaction in the third region is compared to that in the first and second regions.

Abstract: The object of the invention is a passive planar thermo-optical structure for detection of a region of changed temperature on patient's skin, comprising a thermoactive dye. The thermo-optical structure according to the invention has a layered structure comprising a transparent film layer (102), a thermochromic layer (103), a securing layer (105), an adhesive layer (106), and a protective layer (107). At least a portion of surface of the transparent layer (102) forms a screen (102a). At least one dye in the thermochromic layer is characterised in that above a temperature threshold having value within the range of 31° C. to 37° C. it adopts the first colour and keeps it in a temperature range greater than or equal to 0.6° C., and the width of the temperature range, in which the colour is indefinite, is smaller than 0.3° C. Further, the object of the invention is an application of the thermo-optical detector according to any of claims 1 to 20 for the evaluation of the extent of skin allergic reaction.

Abstract: A thermomastographic apparatus for differentiation diagnostics for detecting breast pathology in women contains thermosensitive liquid crystals deposited on a flexible, transparent base plate of organic polymer as a foil, comprising simultaneously a carrier and a screen. The apparatus comprises two thermographic matrices, each comprising two test plates for simultaneous examination of both breasts, wherein the first matrix is used for detecting pathophysiological changes of hypothermal expression, and the second matrix is used for detecting pathophysiological changes of hyperthermal expression, in relation to physiological human temperature of 36.6° C., and wherein each test plate is U-shaped and contains at least one monomolecular, continuous layer comprised of a homogenized mixture of liquid crystals exhibiting a thermooptical effect and sealed with elastomer.