Patents by Inventor Jack A. PARENT

Jack A. PARENT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STEM CELL DERIVED SINGLE-ROSETTE BRAIN ORGANOIDS AND RELATED USES THEROF
    Publication number: 20230151336
    Abstract: The invention disclosed herein generally relates to methods and systems for converting stem cells into specific tissue(s) or organ(s) through directed differentiation. In particular, the invention disclosed herein relates to methods and systems for promoting human self-organizing single-rosette spheroids (SOSRS), a type of brain organoid, comprising neuroepithelium having either a dorsal cell fate or a ventral cell fate formation from pluripotent stem cells.
    Type: Application
    Filed: April 22, 2021
    Publication date: May 18, 2023
    Inventors: Jack Parent, Andrew Tidball
  • MODEL SYSTEMS FOR SCREENING MODULATORS OF mTOR SIGNALING
    Publication number: 20170261495
    Abstract: The presently disclosed subject matter relates to the generation of induced pluripotent stem cell (iPSC)-derived neuronal cell lines from subjects diagnosed with polyhydramnios-megalencephaly-symptomatic-epilepsy (PMSE) and assays making use of such cell lines to identify mammalian target of rapamycin (mTOR) signalling modulators as well as anti-epileptogenic compounds.
    Type: Application
    Filed: May 25, 2017
    Publication date: September 14, 2017
    Applicant: SHRINERS HOSPITALS FOR CHILDREN
    Inventors: Peter B. CRINO, Jack A. PARENT