Patents by Inventor Jack A. Tuszynski

Jack A. Tuszynski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR TREATING ALZHEIMER'S DISEASE USING SUPERIOR STABILITY TUBULIN CONSRUCTS
    Publication number: 20160361385
    Abstract: A method of providing a therapeutic benefit to a patient for Alzheimer's Disease (AD) is disclosed. A superior stabilizing-tubulin (SS-tubulin) is administered, either directly or indirectly through gene therapy. Mutated alpha SS-tubulins and mutated beta SS-tubulins are disclosed for use in the method.
    Type: Application
    Filed: June 13, 2016
    Publication date: December 15, 2016
    Inventors: Jack A. Tuszynski, Nancy Woolf
  • SYSTEMS AND METHODS OF SELECTING COMPOUNDS WITH REDUCED RISK OF CARDIOTOXICITY
    Publication number: 20150193575
    Abstract: Provided herein are systems and methods for selecting compounds that have reduced risk of cardiotoxicity or which are not likely to be cardiotoxic. As an example, a system and method can include a computational dynamic model combined with a high throughput screening in silico that mimics one of the most important ion channels associated with cardiotoxicity, namely the human Ether-a-go-go Related Gene (hERG) channel. Also provided herein are systems and methods for redesigning compounds that are predicted to be cardiotoxic based on the model and the high throughput screening.
    Type: Application
    Filed: December 12, 2014
    Publication date: July 9, 2015
    Inventors: Michael Houghton, Jack A. Tuszynski, Khaled Barakat, Anwar Mohamed
  • Method for designing an aptamer
    Patent number: 8484010
    Abstract: Disclosed in this specification is a method for identifying at least one aptamer that can bind to a bio-molecular target. The aptamer is designed in silico based on the structure of the target molecule. The process includes the steps of determining a first seed residue and growing an oligomer, one residue at a time, while maximizing the entropy of target-oligomer complex or minimizing the binding energy after the addition of each oligomer.
    Type: Grant
    Filed: November 17, 2011
    Date of Patent: July 9, 2013
    Assignee: Technology Innovations, LLC
    Inventors: Jack A. Tuszynski, Chih-Yuan Tseng
  • PROCESS AND APPARATUS FOR TREATING BIOLOGICAL ORGANISMS
    Publication number: 20120185016
    Abstract: Disclosed in this specification is an apparatus and method for treating a biological organism comprising a device for emitting and delivering energy to the biological organism, a programmable controller for varying the type and amount of energy emitted, and apparatus for sensing a condition of the biological organism.
    Type: Application
    Filed: December 20, 2011
    Publication date: July 19, 2012
    Applicant: Biomed Solutions LLC
    Inventors: Michael L. Weiner, Robert W. Gray, Stuart G. MacDonald, Jack A. Tuszynski, Amara D. Angelica, Kendrick Goss
  • METHOD FOR DESIGNING AN APTAMER
    Publication number: 20120123760
    Abstract: Disclosed in this specification is a method for identifying at least one aptamer that can bind to a bio-molecular target. The aptamer is designed in silico based on the structure of the target molecule. The process includes the steps of determining a first seed residue and growing an oligomer, one residue at a time, while maximizing the entropy of target-oligomer complex or minimizing the binding energy after the addition of each oligomer.
    Type: Application
    Filed: November 17, 2011
    Publication date: May 17, 2012
    Applicant: Technology Innovations, LLC
    Inventors: Jack A. Tuszynski, Chih-Yuan Tseng
  • Process and apparatus for treating biological organisms
    Publication number: 20080287856
    Abstract: An apparatus for treating a biological organism comprising a device for emitting and delivering energy to the biological organism, a programmable controller for varying the type and amount of energy emitted, and apparatus for sensing a condition of the biological organism.
    Type: Application
    Filed: June 10, 2008
    Publication date: November 20, 2008
    Applicant: Biomed Solutions LLC
    Inventors: Stuart G. MacDonald, Jack A. Tuszynski, Kendrick Goss, Michael L. Weiner, Robert W. Gray, Amara D. Angelica
  • Compositions and methods for the treatment of malaria
    Patent number: 7265248
    Abstract: A colchicine derivative and a method of using a colchicine derivative as a pharmacological agent in the treatment of malaria are provided.
    Type: Grant
    Filed: April 28, 2006
    Date of Patent: September 4, 2007
    Assignee: Technology Innovations, LLC
    Inventors: Jack A. Tuszynski, Stephen H. Curry