Patents by Inventor Jack Anthony BATES

Jack Anthony BATES has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AGONISTIC SPLIT ANTIBODIES
    Publication number: 20260176377
    Abstract: The application relates to pairs of antigen binding molecules, each molecule comprising a target-binding domain, a cytokine receptor-binding domain and an Fc domain, wherein the target-binding domains simultaneously bind the target antigen and the cytokine receptor-binding domains bind subunits of a cytokine receptor complex. Biparatopic assembly of the cytokine receptor-binding domains in presence of the target antigen allows to selectively activate a cytokine receptor and effectively mimic cytokine activity in a targeted manner.
    Type: Application
    Filed: October 2, 2025
    Publication date: June 25, 2026
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Petra Elisabeth Marilena BALBI, Jack Anthony BATES, Samuele CALABRO, Laura CODARRI DEAK, Stephan GASSER, Guy GEORGES, Xavier GUERIPEL, Ralf Joerg HOSSE, Christian KLEIN, Stéphane Gérard Alain LECLAIR, Ekkehard MOESSNER, Christian MUELLER, Diana Angela PIPPIG, Laurene POUSSE, Camilla Elizabeth TREVOR, Pablo UMAÑA FERNÁNDEZ
  • ALL-IN-ONE AGONISTIC ANTIBODIES
    Publication number: 20260085113
    Abstract: The application relates to antigen binding molecules comprising a pair of biparatopic target-binding domains, a pair of cytokine receptor-binding domains and an Fc domain, wherein the target-binding domains simultaneously bind the target antigen and the cytokine receptor-binding domains bind subunits of a cytokine receptor complex. Biparatopic assembly of the cytokine receptor-binding domains in presence of the target antigen allows to selectively activate cytokine receptors and effectively mimic cytokine activity in a targeted manner.
    Type: Application
    Filed: October 2, 2025
    Publication date: March 26, 2026
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Petra Elisabeth Marilena BALBI, Jack Anthony BATES, Samuele CALABRO, Laura CODARRI DEAK, Stephan GASSER, Guy GEORGES, Xavier GUERIPEL, Ralf Joerg HOSSE, Christian KLEIN, Stéphane Gérard Alain LECLAIR, Ekkehard MOESSNER, Christian MUELLER, Diana Angela PIPPIG, Laurene POUSSE, Camilla Elizabeth TREVOR, Pablo UMAÑA FERNÁNDEZ
  • TARGETED INTERFERON ALPHA FUSION PROTEINS AND METHODS OF USE
    Publication number: 20240376205
    Abstract: The invention provides fusion proteins that comprise a human IFN-?2, a first antigen-binding domain capable of binding to human PD-L1, a second antigen-binding domain capable of binding to human PD-L1 and to human IFN-?2, and methods of using the same.
    Type: Application
    Filed: May 7, 2024
    Publication date: November 14, 2024
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Jack Anthony BATES, Davide BERTOLDO, Ulrich BRINKMANN, Harald DUERR, Moritz RAPP, Jasmin SYDOW-ANDERSEN, Pablo UMAÑA, Monika WOLF