Patents by Inventor Jack D. SOBEL

Jack D. SOBEL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12509734
    Abstract: Systems and methods to assess the health of various microbiomes and to identity species therein are disclosed. Described assessments and identifications can inform treatment decisions if a microbiome is determined to have a less than optimal balance of bacterial species within it; the presence of one or more negative species; and/or the absence of one or more positive species.
    Type: Grant
    Filed: October 19, 2021
    Date of Patent: December 30, 2025
    Assignee: Wayne State University
    Inventors: Robert A. Akins, Jack D. Sobel
  • Publication number: 20250268934
    Abstract: Provided herein are methods of treating vaginitis by simultaneous local application per vagina of both boric acid and nitroimidazole. Also provided are compositions useful in such treatments, for instance containing 100-1,000 mg of nitroimidazole and 300-900 mg boric acid. Vaginal application of nitroimidazole allows a higher but safe dose to be administered simultaneously with boric acid for the effective treatment of bacterial vaginosis (BV). Also provided are methods for prophylactic treatment of patients, such as those prone to recurrent BV.
    Type: Application
    Filed: April 14, 2023
    Publication date: August 28, 2025
    Applicants: Wayne State University, Aolis Investment AG
    Inventors: Jack D. Sobel, Koral Embil
  • Publication number: 20220049290
    Abstract: Systems and methods to assess the health of various microbiomes and to identity species therein are disclosed. Described assessments and identifications can inform treatment decisions if a microbiome is determined to have a less than optimal balance of bacterial species within it; the presence of one or more negative species; and/or the absence of one or more positive species.
    Type: Application
    Filed: October 19, 2021
    Publication date: February 17, 2022
    Applicant: Wayne State University
    Inventors: Robert A. Akins, Jack D. Sobel
  • Patent number: 11186880
    Abstract: Systems and methods to assess the health of various microbiomes and to identity species therein are disclosed. Described assessments and identifications can inform treatment decisions if a microbiome is determined to have a less than optimal balance of bacterial species within it; the presence of one or more negative species; and/or the absence of one or more positive species.
    Type: Grant
    Filed: April 5, 2019
    Date of Patent: November 30, 2021
    Assignee: Wayne State University
    Inventors: Robert A. Akins, Jack D. Sobel
  • Patent number: 10857216
    Abstract: The invention features methods and kits use in for preventing and treating vulvovaginal candidiasis (VVC), in particular, recurrent VVC.
    Type: Grant
    Filed: March 7, 2017
    Date of Patent: December 8, 2020
    Assignees: NovaDigm Therapeutics, Inc., Los Angeles Biomedical Institute at Harbor-UCLA Medical Center
    Inventors: John E. Edwards, Jr., Scott G. Filler, John P. Hennessey, Jr., Michael Timothy Cooke, Jack D. Sobel
  • Publication number: 20190264263
    Abstract: Systems and methods to assess the health of various microbiomes and to identity species therein are disclosed. Described assessments and identifications can inform treatment decisions if a microbiome is determined to have a less than optimal balance of bacterial species within it; the presence of one or more negative species; and/or the absence of one or more positive species.
    Type: Application
    Filed: April 5, 2019
    Publication date: August 29, 2019
    Applicant: Wayne State University
    Inventors: Robert A. Akins, Jack D. Sobel
  • Patent number: 10253377
    Abstract: Systems and methods to assess the health of various microbiomes and to identity species therein are disclosed. Described assessments and identifications can inform treatment decisions if a microbiome is determined to have a less than optimal balance of bacterial species within it; the presence of one or more negative species; and/or the absence of one or more positive species.
    Type: Grant
    Filed: April 4, 2014
    Date of Patent: April 9, 2019
    Assignee: Wayne State University
    Inventors: Robert A. Akins, Jack D. Sobel
  • Publication number: 20190076512
    Abstract: The invention features methods and kits use in for preventing and treating vulvovaginal candidiasis (VVC), in particular, recurrent VVC.
    Type: Application
    Filed: March 7, 2017
    Publication date: March 14, 2019
    Inventors: John E. EDWARDS, JR., Scott G. FILLER, John P. HENNESSEY, JR., Michael Timothy COOKE, Jack D. SOBEL
  • Publication number: 20160040216
    Abstract: Systems and methods to assess the health of various microbiomes and to identity species therein are disclosed. Described assessments and identifications can inform treatment decisions if a microbiome is determined to have a less than optimal balance of bacterial species within it; the presence of one or more negative species; and/or the absence of one or more positive species.
    Type: Application
    Filed: April 4, 2014
    Publication date: February 11, 2016
    Applicant: Wayne State University
    Inventors: Robert A. AKINS, Jack D. SOBEL