Abstract: The present invention comprises a plurality of injectable hollow particulate fillers suspended in a biocompatible fluid carrier to significantly improve the clumping resistance and injectability of the composition. The hollow particulate fillers have a lower effective density and are able to suspend in the carrier without precipitation. The loss of skin volume as a result of aging, diseases, weight loss, and injury can lead to uneven skin surface (e.g. wrinkle, etc.). The uneven skin can be repaired by injecting appropriate amount of hollow fillers underneath the skin. Some cases of urinary incontinence occur when the resistance to urine flow has decreased excessively. Continence is restored by injecting the present invention to the urethra tissue to increase resistance to urine outflow. Similarly, the present invention allows for the control of gastric fluid reflux by submucosal injections of the fillers to the esophageal-gastric and gastric-pyloric junction.

Abstract: Methods and systems for preventing aneurysm rupture and reducing the risk of migration and endoleak are disclosed. Specifically, an inflatable liner is applied directly to treat the interior of the aneurysm site. Also disclosed are methods to deliver the inflatable liner directly to treatment sites.

Abstract: Methods and systems for preventing aneurysm rupture and reducing the risk of migration and endoleak are disclosed. Specifically, a hardenable liner is applied directly to treat the interior of the aneurysm site. The hardening agent remains flexible in the pliable mode so that the liner can be collapsed and compressed in a delivery catheter. After deploying in the aneurysm, the flexible liner expands by the hemodynamic force and conforms to the inner surface of the aneurysm. While the liner is still conforming to the aneurysm, the hardening agent in the liner is activated by the body environment and becomes stiff. The liner is thus transformed from the pliable mode to the strengthening mode and providing support for the aneurysm wall. Also disclosed are methods to deliver the hardenable liner directly to treatment sites.

Abstract: Methods and systems for preventing aneurysm rupture and reducing the risk of migration and endoleak are disclosed. Specifically, an inflatable multiple walls liner is applied directly to treat the interior of the aneurysm site. Also disclosed are methods to deliver the inflatable multiple walls liner directly to treatment sites.

Abstract: The present invention comprises a plurality of injectable hollow particulate fillers suspended in a biocompatible fluid carrier to significantly improve the clumping resistance and injectability of the composition. The hollow particulate fillers have a lower effective density and are able to suspend in the carrier without precipitation. The loss of skin volume as a result of aging, diseases, weight loss, and injury can lead to uneven skin surface (e.g. wrinkle, etc.). The uneven skin can be repaired by injecting appropriate amount of hollow fillers underneath the skin. Some cases of urinary incontinence occur when the resistance to urine flow has decreased excessively. Continence is restored by injecting the present invention to the urethra tissue to increase resistance to urine outflow. Similarly, the present invention allows for the control of gastric fluid reflux by submucosal injections of the fillers to the esophageal-gastric and gastric-pyloric junction.